HISTOLOGY OF THE GIT

Powerpoint is by Jose Danilo B. Diestro. Picutures are by the entire MDL 9 (D’s and E’s) of
UP MED 2013

Warnings:
5. This powerpoint has not been confirmed by Dr. Mantaring because we only had 1 lab session.
6. Read your lab manual as you view this powerpoint (they are in the same order)
7. Not all structures were labeled.
8. This powerpoint lacks a lot of small intestine details and pancreatic ducts.
GIT: Main Histological Layers
Esophagus: Section Through All Layers
Esophagus: Upper Layers

SSE

Lamina
Propria

Muscularis
Mucosae

Esophageal
Glands in
Submucosa
Esophagus: Muscularis Externa.
Gastro-Esophageal Junction
 Gastro-Esophageal Junction

SSE in
Esophagus
Simple Columnar
in stomach
Stomach
Stomach: Fundus
Stomach: Body
Stomach Pylorus:
Stomach: Simple Columnar Epithelium
Stomach: Muscularis Mucosae
Stomach: Submucosa
Stomach: Muscularis Externa
 Stomach: Gland Cells

Parietal
Cell

Zymogenic
Cell
Stomach: Myenteric Plexus of Auerbach
Small Intestine: Duodenum

Brunner’s Glands
Small Intestine: Duodenum
Small Intestine: Ileum

Compare with duodenum that DOES NOT HAVE PC. PC also has
submucosa at it’s core. While villi only have lamina propria.
 Small intestine: Villi Versus Plicae Circulares

Don’t forget that villi are on the luminal surface of plicae circulares! PC is like a “pulled up” version of plain villi
taking even the muscularis mucosae and submucosal layer with it.

Villi only (Early Duodenum) Villi on Plicae Circulares (Late duodenum –

Early Jejunum)
Small Intestine: Intestinal Villi
Small Intestine: Intestinal Villi
 Small Intestine: Crypt of Lieberkuhn

Smaller Blood Vessel Goblet

in Lamina Propria Cell

Enteroendocrine
Cell

Paneth
Cell

Blood Vessel in Muscularis

Submucosa Mucosae
Small Intestine: Crypts of Lieberkuhn
Large Intestine
Large Intestine
Appendix
 Appendix

Crypts in the Lamina

propria
 Appendix: More crypts in the Lamina Propria

Lymphoi
d cells
 Appendix: Serosa and muscular layers

Serosa

Muscular
Layers
 Rectum

Crypt

Lamina
Propria
Goblet
cells

Muscularis
Mucosae

Submucosa
Liver: Glisson’s Capsule
 Liver: Overview and Glisson’s Capsule

Glisson’s
Capsule

Try to identify the hepatic sinusoids, portal

tract, hepatocyte layers (elaborated on next
slides)
Liver: Pattern of Central Vein and Portal Tract
Liver: Central Vein and Portal Tract
 Liver: Central Vein and Hepatic Tract

NOT Hepatic
Sinusoid
Cenral
Vein
 Liver: Portal Tract

Portal Vein Branch

Biliary
Duct Hepatic
Artery
Branch
 Liver: Portal Tract

Lymphatic
Vessel Hepatic
Artery
branch

Branch of
Portal Vein

Biliary
Duct
 Liver: Hepatic Sinusoids and Hepatocytes

Hepatocyte Sinusoid
Liver: Kupffer Cells and Sinusoid lining
Liver: Reticular Fibers

Reticular
Fibers
Gall Bladder
 Gall bladder

Blood Vessel in
Lamina Propria

Simple Columnar
Epithelium
 Gall Bladder: Rokitansky- Aschoff sinuses

Lamina
Propria

Submucosa

Muscular
Layers

Blood Vessel in
Adventitia
Pancreas
Pancreas: Exocrine Portion
 Pancreas

Intralobul
ar duct

Interlobular
duct
Pancreas
Pancreas
Generalizations on the GIT
Generalizations on the GIT
Generalizations on the GIT
Quiz: What are these structures?
Quiz

1. What is this organ?

2. What is the Yellow Circle encircling
3. How about the green circle
Quiz

1. What parts of the

portal tract are seen?
2. What organ has a
portal tract?
3. What are entities are
stained black?
Quiz

2. What glands in
what layer?

1. What
organ?
Quiz: What is part of the gall bladder is the pointer in?