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SELAMAT PAGI

RM. Teguh Wahjudi dr,MS,AFK

BENTUK SEDIAAN OBAT


DISPENSING FORMS OF DRUG

Dr.M.Teguh Wahjudi MS,AFK,PKK

BENTUK SEDIAAN OBAT


BENTUK CAIR ( LIQUID ) BENTUK SETENGAH PADAT ( SEMI LIQUID) BENTUK PADAT (SOLID )

BENTUK OBAT PADAT


Serbuk (pulvis). Serbuk terbagi (pulveres). Tablet . Kapsul Sapo Emplastrum Susuk

BENTUK OBAT SETENGAH PADAT


Salep Cream Pasta Suppositoria

BENTUK OBAT CAIR


Solutio Mixtura Mixtura Agitanda Suspensi Emulsi Saturatio Guttae Galenical Nebula /Aerosol Injectio

KRITERIA MEMILIH BENTUK OBAT


1.FAKTOR OBAT :
Fisik obat. Kimia obat. Onset & duration of action Rasa pahit. Iritasi lambung.

2.FAKTOR PENDERITA :
Anak dewasa tua Compos mentis - coma

BENTUK OBAT CAIR

SOLUTIO ( LARUTAN )
ZAT PADAT DALAM ZAT CAIR LARUT TIDAK ADA ENDAPAN JERNIH - HOMOGEN

PELARUT :
-AIR -ALKOHOL -ETHER -PROPPYLEN GLYCOL -MINYAK -PARAFIN LIQUIDUM

KELARUTAN :
-SOLUTE -SOLVEN -TEMPERATUR -pH

-GLYSERIN

R/ Acidi Borici

6 200 ml

Aquadest ad 100ml

S Boorwater
---------- paraf

R/ Acidi Borici Aquadest ad S Boorwater

3% 100ml

3% 200 ml

---------- paraf

R/ Jodii Natrii Jodid Spir 50% ad rec.par

2 2,5 100ml

S u.e.
---------- paraf

R/ Solutio Jodii spir. 2% 100 ml


rec.par S u.e

---------- paraf

R/ Jodium tincture 100 ml rec. par S u.e ---------- paraf

R/ Jodii
Kalii Jodii Aqua ad

0,50
0,100 25 ml

f.l.a

Sol

S t.dd gtt XV -----paraf

R/ Solutio Lugolli S 3 dd. gtt XV ------ paraf

25 ml

R/ Succus liquiritiae
Ammonii Chlorid

5
3 3

Sol.Ammonii spir. Anis

Aquadest ad
S 3 dd C I -----paraf

150 ml

R/ Potio Nigra contra tussim S 3 dd. C. I -----------------paraf

150 ml

R/ O.B.H S 3

150 ml dd. C.I -----paraf

Sasa tdd :
-Ammonia -Ammon. Carbonat -Various oils -Spir. dil

R/ Zinci Chlorid Kalii et . Alum. Sulfat Acid Salicylic gtt

1 1 0,300 II

Ol. Menthe Pip

Aqua
Filtra S

ad

300ml

garg. 3

dd
paraf

------------ ----------

R/ Garg
S

Kan
3

300 ml
dd
paraf

garg.

------ ---- --------

R/ Ascal Natrii Bromidi Aquadest S 3 ad pc

10 5 300 ml prn paraf

dd C.I -------- ----

MIXTURA
HCl + air Alkohol + air : 70% Spir. Dil 95% - 96% Spir. Fortior. Homogen tidak ada endapan tercampur secara molekuler

R/ Methyl Salicylic
Ol.Cayuputi Chloroform

20
20 20

Inf. Hioscyami oleos 20


S a.u.e ------------paraf

R/ Gandapura
S u.e

80 ml

----------------

paraf

R/ Sasa Syr. Simplex

2 ml 10 ml gtt I 100 ml Cth I paraf

Ol. Menthe pip Aquadest S 4-6 ad dd

-------------

R/ Potio Alba contra tussim


S 4-6 dd Cth I paraf

100 ml

------ -------

R/

O .B .P S 4-6 dd

100 ml Cth I

------ -------

paraf

MIXTURA AGITANDA
R/ Acid Salicylic Zinci Oxyde Talc.Venet Amyl.Orizae 1 10 10 10 R/ Calamine Zinci Oxyde Glycerin Aqua Rosae ad S u.e ------ paraf 8 8 5 ml 100 ml

Alcohol 90% ad 200 ml S u.e ------ paraf

SUSPENSIO

DEFINISI :
SUSPENSATOR : A.ALAMI B.SYNTHETIC

SUSPENSATOR
ALAMI GUMMI ARAB : Pulv. Solutio Mucilago TRAGACANTH :Sol. Mucilago AMYLUM :Mucilago AGAR DLL SYNTHETIC CMC Bentonit Tween

R/ Paracetamol 2880 mg Syr. Simplex 15% CMC 1,5 % Aqua ad 120 ml f.l.a susp S 3 dd cth II ------ paraf

R/ Ampicillin Syr simplex Orange gtt CMC Aqua ad m.f.l.a susp S 3 dd cth I ----- paraf

50 mg
qs 1,5 % 60 ml

R/ Tetracycline 2,3 CMC Na 1% Sol. Sorbitol 60% 20 ml Saccharin Na 0,100 Sir.Simplex 20 ml Glycerin 3,5ml Corrigens (orange) gtt qs Aquadest ad 100 ml m f l a susp S . . . . .. ----- paraf R/ Syrop Tetracycline ml S 2 dd cth I
----- paraf

R/ Syrop Tetracycline .ml S......... ----- paraf

R/ Magnesium hydroxyde 2400 mg Al. hydroxyde 2400 mg Simethicon 240 mg Gummi Arab 2% Ol. Menthe pip gtt II Aquadest ad 60 ml m f l a susp S loco Mylanta susp 3 4 dd cthI cth II ----- paraf

R/ Trimetoprim 480 mg Sulfametoxazole 2400 mg Sir. Simplex 10 % 20 % P.G.A 2% Strawberry qs Aquadest ad 60 ml m f l a susp S Susp Cotrimoxazole 2 dd cth I ------ paraf

R/ Sulfasomidin CMC Saccharosa Methyl hydroxy benzoat Propyl hydroxy benzoat Sol.Amaranth 1 % Aquadest ad S .....
----- paraf

10 1% 30 % 0,015 % 0,015 % gtt V 100 ml

R/ Sirop Elkosin S ........


----- paraf

100 ml

R/ Sulfadiazine Natrii bicarb. aa Sir. Aurantii Sol. Gumoss ad 3 dd C I


----- paraf

10 30 300 ml

R/ Sulfadiazine Sasa Calcii lactas Sir. Simplex Pulv. Gummos Aquadest ad KSHD
------- paraf

5 1 4 10 2 150

EMULSIO
Emulgator ~ Suspensator

R/ Ol. Zecoris aselli 40 Ol. Cinnamomi 0,100 Pulv. Gi Arab 15 Natr Hypophospis 0,500 Calc Hypophospis 0,500 Aquadest 20 Glyserin 10 Aquadest 14 m f l a emuls loco Scotts emulsion ----- paraf

R/ Benzylis Benzoas 25 Triethanol amine 1 Acid Stearinic 5 Aqua ad 100 ml m f l a emulsi S u.e
----- paraf

R/ B.B.E 25 % S u.e
----- paraf

100 ml

GALENICALS
PELARUT ALKOHOL TINCTURE AIR + ALKOHOL/ETHER EXTRACT AIR 90OC / 15 INFUSUM AIR 90oC / 30 DECOCTUM

PREPARAT GALENIK
1.DENGAN PEMANASAN
90oC 15 : INFUSUM 30 : DECOCTUM

2.TANPA PEMANASAN ( SUHU KAMAR) * 4 5 hari maceratio * Diulang / remaceratio percolatio Hasil maceratio/ remaceratio : Extractum Tinctura

Extract :
CAIR : Extract Secale Cornuiti KENTAL : Extract Belladona KERING : Extract Opii

Tincture
TOXIC : Kadar 10% Tinctura Opii Tinctura Belladona Tinctura Digitalis NON TOXIC : Kadar 20% Tinctura Valeriane

Infusum
R/ Folia Piperie betle Natrii Chlorid Aqua f. Infus S garg. 4 dd
----- paraf

20 4 qs 200 ml

R/ Folia Digitalis Aqua Alkohol Spirit Cinnamomi f. Infus S 3 dd cth II


----- paraf

15 g 900 ml 100 ml 5 ml 1000 ml

NEBULA /AEROSOL

Gas : -dichloro difluoro methane -trichloro monofluoro methane -dichloro tetrafluoro methane Nama dagang : -Freon -Genetron -Isotron -Ucon

GUTTAE

1 ml H2O ~ 1 g H2O = 20 tetes

R/ Zinci Sulfate 0,25 % Aqua ad 10 ml f.Steril S 3 dd gtt II OD/OS ----- paraf

SIRUPUS
R/ Sukrose 65 % Aqua ad 1000 ml sirupus simplex
---- paraf

SATURATIO
R/ Acid Citric Aqua Spir Citri Sir.Simplex Natr. Bicarbonat Aqua Potio Riveri 2,5 25 2,5 12,5 3 55

----- paraf

Injectio / Suntik
Tujuan, Keuntungan, Kerugian Syarat, Bentuk, Wadah

TERIMA KASIH