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RASAOUSHADHIS AND

BHASMAS IN THE
MANAGEMENT OF
ARBUDA

DR. SANTHOSH B
DEPT. OF
Rasoushadhis and bhasmas used
30/07/09 2
in Arbuda
Objectives
• To understand the samprapti of
Arbuda

• To know different treatment


modalities

• To know where we can use


rasoushadhis
Rasoushadhis and bhasmas used
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in Arbuda
Derivation
 Derived from the root Arb with suffix
Ena and along with ‘Nd’

 Destroy particularly the Mamsa


Dhatu.

 Denotes the fleshy out growths

Rasoushadhis and bhasmas used


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in Arbuda
Cancer
• Dervied from Greek word
– ‘Karkinos’meaning
Crab.
• Appearance of large prominent veins
surrounding the growth, encircled
the mass like claws of a crab.

Rasoushadhis and bhasmas used


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in Arbuda
Definition
• Large Glandular enlargement

• A growth of new cells which


proliferate without relation to needs
of body - Tumour

• Types - Benign
- Malignant
Rasoushadhis and bhasmas used
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in Arbuda
Mechanism
of
Carcinogen
Rasoushadhis and bhasmas used
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in Arbuda
• Initiation

A single brief exposure to a


carcinogen induces changes in the
tissue

 The nature of the structural


alterations in initiated cell is diverse

 Chemicals and ultra violet radiations


directly alter DNA structure
Rasoushadhis and bhasmas used
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in Arbuda
• Promotion

 Ability of a compound to induce an


area of proliferation in initiated tissue
and stimulate tumour formation

 Dietary fat has been implicated as a


tumour promoter in the development
of colon cancer

Rasoushadhis and bhasmas used


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in Arbuda
• Progression

Usually refers to the later stage of


tumour cell evolution that are
irreversible

 Once the tumour develops,


individual traits such as hormone
responsiveness, growth rate,
histologic type and invasiveness,
function as independent variables
capable of progression
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Rasoushadhis and bhasmas used
10
in Arbuda
• Metastasis

 Active process consisting of 3 stages


 attachment of cells to extra-cellular matrix

 local degradation of extra-cellular matrix

 locomotion through the locally degraded matrix

 The spread of tumour from a primary lesion


to a distant site is a major cause of
morbidity and mortality

 Once the tumour cell has migrated to a


metastatic site, additional metastatic foci
may occur by repetition of these types
Rasoushadhis and bhasmas used
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in Arbuda
Mechanism of Invasion &
Metastasis
• Metastasis, the establishment of
tumour cells at distant sites in the
body, is the hallmark of cancer
• Tumour cells must acquire the ability to
:
 Invade stroma
Stimulate neoangiogenesis
 Transgress stroma
 Invade vessel walls
 Extravasate into the extra vascular
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Rasoushadhis and bhasmas used
12
in Arbuda
Stem
Initiation event Cell
Initiated Cell
Promotion event
Pre – Cancer Cell
Conversion event

Cancer Cell
Progression event

30/07/09
Rasoushadhis and bhasmas used Metastatic 13
in Arbuda
Sushruta
uÉÉiÉÉSrÉÉå qÉÉÇxÉqÉxÉ×Mçü
cÉ SÒ¹ÉÈ l
xÉlSÕwrÉ qÉåS¶É
MüTüÉlÉÑÌuÉ®qÉç ll
uÉרÉÉå³ÉiÉÇ ÌuÉaÉëÍjÉiÉÇ iÉÑ
zÉÉåTÇü l
MÑüuÉïlirÉiÉÉå aÉëÎljÉËUÌiÉ
mÉëÌS¹È ll
Rasoushadhis and bhasmas used
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in Arbuda
Charaka

ÌuÉmÉÉš cÉÉå®ØirÉ ÍpÉwÉMçü


xÉMüÉåzÉÇ zÉx§ÉåhÉ SakuÉÉ
uÉëhÉuÉΊÌMüixÉåiÉç

shotha
chikitsa
Rasoushadhis and bhasmas used
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in Arbuda
Su. Ni. 11 / 13-15
aÉɧÉmÉëSåzÉå YuÉÍcÉSåuÉ SÉåwÉÉÈ
xÉqqÉÔÎcNïûiÉÉ
qÉÉÇxÉqÉÍpÉmÉëSÕwrÉ
uÉרÉÇ ÎxjÉUÇ qÉlSÂeÉÇ
qÉWûÉliÉqÉlÉsmÉqÉÔsÉÇ
ÍcÉUuÉ×SèkrÉmÉÉMüqÉç
MÑüuÉïÎliÉ qÉÉÇxÉÉåmÉcÉrÉÇ iÉÑ
zÉÉåTÇü iÉSoÉÑïSÇ zÉÉx§ÉÌuÉSÉå
uÉSÎliÉ
Rasoushadhis and bhasmas used
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in Arbuda
SÉåwÉÈ mÉëSÒ¹Éå ÂÍkÉUÇ ÍxÉUÉxiÉÑ
xÉqmÉÏŽ xɃ¡ûÉåcrÉ
aÉiÉxiÉÑmÉÉMüqÉç
xÉÉxÉëÉuÉqÉѳɽÌiÉ qÉÉÇxÉÌmÉhQÇû
qÉÉÇxÉɃ¡ÓûUæUÉÍcÉiÉqÉÉzÉÑ
uÉ×ήqÉç
xÉëuÉirÉeÉxÉëÇ ÂÍkÉUÇ
mÉëSÒ¹qÉxÉkrÉqÉåiÉSìÓÍkÉUÉiqÉMÇ
ü xrÉÉiÉç
30/07/09
Rasoushadhis and bhasmas used
in Arbuda
17
qÉÑ̹mÉëWûÉUÉÌSÍpÉUÌSïiÉåÅ…¡åû
qÉÉÇxÉÇ mÉëSÒ¹Ç mÉëMüUÉãÌiÉ
zÉÉåTüqÉç
AuÉåSlÉÇ
ÎxlÉakÉqÉlÉlrÉuÉhÉïqÉmÉÉMüqÉzqÉÉ
åmÉqÉqÉmÉëcÉÉsrÉqÉç
mÉëSÒ¹qÉÉÇxÉxrÉ lÉUxrÉ
oÉÉRûqÉåiÉ°uÉålqÉÉÇxÉmÉUÉrÉhÉxr
É
qÉÉÇxÉÉoÉÑïSÇ iuÉåiÉSxÉÉkrÉqÉÑ£Çü
Rasoushadhis and bhasmas used

......
30/07/09 18
in Arbuda
CLASSIFICATION OF
ARBUDA

Rasoushadhis and bhasmas used


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in Arbuda
AmÉÉMü ?
• MüTüÉÍkÉMüiuÉ
• qÉåSÉåÅÍkÉMüiuÉ
• SÉåwÉÎxjÉUiuÉ
• aÉëjÉlÉÉŠ iÉåwÉÉÇ

Rasoushadhis and bhasmas used


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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
SAMPRAPTI OF
ARBUDA

Rasoushadhis and bhasmas used


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in Arbuda
Nija - Mamsahara Nidana sevana
Agantuja - Mushtipraharad

Sanchaya
Agnimandya Dhatwagni mandya
Prasara
Prakopa
Dosha prakopa Rakta & mamsa dushti

Sroto Dushti

Sthana Samshraya
Khavaigunya

Arbuda – Mamsarbuda - Raktarbuda Vyakti

Dwirarbuda - Adhyarbuda Bheda


Rasoushadhis and bhasmas used
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in Arbuda
SAMPRAPTI GHATAKA
Dosha : Kapha and Vata predominant

Dushya :Mamsa, Meda and Rakta

Srotas :Mamsa, Meda and Raktavaha

Sroto dushti : Sanga and Sira granthi

Agni : Jatharagni & Dhatwagni

Rogamarga :Bahya

Udbhavsthana : Anywhere in the body


Adhisthana : Sixth layer of the Skin - Rohini

Pratyatma Linga: Mamso Pachaya Tu Shopham


Rasoushadhis and bhasmas used
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in Arbuda
Lung Cancer
A coronal CT
scan 
Showing
malignant
cancer of the
lung.
→ tumor ←
★ central pleural
effusion
1 & 3 lungs
2 spine
4 ribs
Rasoushadhis and bhasmas used
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in Arbuda
5 aorta
Rasoushadhis and bhasmas used
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in Arbuda
AETIOLOGY
• Genetics

• Changes in lifestyle especially in diet


and regimen

• Highly polluted environment

Rasoushadhis and bhasmas used


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in Arbuda
COMMON SITES
T – THYROID
O – ORAL
P – PROSTATE
U – UTERUS
B – BREAST
L – LUNGS
I – GIT
K – KIDNEY
Rasoushadhis and bhasmas used
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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
BENIGN
MALIGNANT
 BOUNDARIES–
encapsulated or • Poorly
well circumscribed circumscribed &
 SIZE–usually small irregular
 SECONDARY • Often large
CHANGES– occur
less often • More often
 PATTERN–
usually • Often poor
resembles the resemblance
tissue of origin
Rasoushadhis and bhasmas used
closely
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in Arbuda
32
• NUCLEOCYTOPLAS
• Increased
MIC RATIO–normal
• FUNCTION–usually
well maintained • May be retained,
lost or abnormal
• GROWTH RATE–
slow • Rapid
• LOCAL INVASION– • Usually infiltrates
often compresses the adjacent
the surrounding tissues
tissues without
invading or
infiltrating them • Frequently present
• METASTASIS–Rasoushadhis and bhasmas used
30/07/09 33
absent in Arbuda
STAGING IN CANCER
• TNM staging

T – tumour
N – lymph node
involvement
M – metastasis

Rasoushadhis and bhasmas used


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in Arbuda
TNM CLASSIFICATION
T1 < OR = to 2 cm

T2 > Than 2 & = to 4


cm
T3 > Than 4 cm

T4 Adjacent
structures involved
N1 Unilateral single
node > than 3 to
30/07/09
in Arbuda 6 cm
Rasoushadhis and bhasmas used
35
N2a bilateral single node
>than 3 to 6 cm
N2b unilateral multiple
nodes < or = to 6 cm
N2c Bilateral or
contralateral nodes <
N3 or
Any= node
to 6cm(s) > than
6cm
M0 No detectable distant
metastasis
M1 Distant metastasis
present
Rasoushadhis and bhasmas used
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in Arbuda
Prognosis
• Susrutha

Sadhya Asadhya
Vataja Mamsaja
Pittaja Adyarbuda
Kaphaja Dvirarbuda
Medoja Raktaja

Rasoushadhis and bhasmas used


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in Arbuda
Treatment of Cancer
• Specific • Supportive

 Surgical Removal  Blood Product


 Radiation Therapy Transfusions
 Chemotherapy  Indwelling Central
Catheters
 Enteral And Para-
enteral Nutrition

Rasoushadhis and bhasmas used


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in Arbuda
Liposarcoma – Medo arbuda

Rasoushadhis and bhasmas used


30/07/09 39
in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
rÉÉåaÉU¦ÉÉMüU

aÉëÎljÉwuÉÉqÉåwÉÑ MÑüuÉÏïiÉ
ÍpÉwÉYzÉÉåjÉmÉëÌiÉÌ¢ürÉÉqÉç l
mÉYuÉÉlÉÉqÉç mÉÉš
xÉÇzÉÉåkrÉUÉåmÉrÉåSèuÉëhÉ
pÉåwÉeÉæÈ ll

• rÉuɤÉÉU + ÌuÉQû…¡û oÉÏeÉ + aÉlkÉMü


qÉSïlÉ
ÌaÉUÌaÉOû MüÉ U£ü sÉåmÉ

aÉlkÉÍzÉsÉÉÌuɵÉÉæwÉkÉÌuÉQûÉ…
¡ûlÉÉaÉpÉxqÉÍpÉÈ xÉqÉæ¶ÉÔhÉïqÉç l
30/07/09
Rasoushadhis and bhasmas used
41
in Arbuda
Vanagasena – Arbuda
chikitsa

eÉrÉå̲SìÍkÉuÉimÉÔuÉïqÉoÉÑïSÇ
mÉëcNûlÉÉÌSÍpÉÈ l
¤ÉÉUÉÎalÉprÉÉÇ SWåûŠÉÌmÉ
mÉëSåWæûÌuÉïÌuÉkÉæeÉïrÉåiÉç ll

WûËUSìÉ sÉÉåkÉë mÉiÉ…¡û aÉ×WûkÉÔqÉ


qÉlÉÈÍzÉsÉÉ l

30/07/09
qÉkÉÑ mÉëaÉÉRûÉå sÉåmÉÉåÅrÉÇ
Rasoushadhis and bhasmas used
42
in Arbuda
Frequently Used
Rasoushadhis
• ApÉëMü pÉxqÉ
• zÉÇZÉÌuÉwÉ pÉxqÉ
• iÉÑijÉ pÉxqÉ
• WûÏUMü pÉxqÉ
• xÉÑuÉhÉï pÉxqÉ
• iÉÉqÉë pÉxqÉ
• UÉæSì UxÉ
• AoÉÑïSWûUÉå UxÉ
Rasoushadhis and bhasmas used
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in Arbuda
Rasendra sara sangraha

• UÉqÉoÉÉhÉÉÌSMüÉlÉç
rÉÉåaÉuÉÉÌWûlÉÉåŧÉ
mÉërÉÉåeÉrÉåiÉç l

Rasoushadhis and bhasmas used


30/07/09 44
in Arbuda
pÉÉUiÉ pÉæwÉerÉ U¦ÉÉMüU
• rÉÉåaÉuÉÉÌWû mÉërÉÉåaÉ :

 AaÉlkÉZÉmÉïU mÉmÉïÌOû
 AÎalÉMÑüqÉU UxÉ (31)
 AqÉU xÉÑlSU UxÉ
 AµÉMÇücÉÑMüÐ UxÉ
 A͵ÉlÉÏ MÑüqÉU UxÉ
 AÉUÉåarÉ xÉÉaÉU UxÉ
 ESrÉ pÉÉxMüU UxÉ
 EqÉÉzÉqpÉÑ UxÉ
 MüÉliÉsÉÉåWû UxÉ
Rasoushadhis and bhasmas used
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in Arbuda
Main Drugs
• mÉÉUS
• aÉlkÉMü
• uÉixÉlÉÉpÉ

Rasoushadhis and bhasmas used


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in Arbuda
Roudra Rasa
• References :
 Rasendra sara sangrah
 Rasa chandamshu
 Rasa raja sundara
 Bhruhannighantu ratnakara
 Rasa kamadhenu
Rasoushadhis and bhasmas used
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in Arbuda
zÉÑ® xÉÔiÉÇ xÉqÉÇ aÉlkÉÇ
qɱïÇ rÉÉqÉcÉiÉѹrÉÇ l
lÉÉaÉuÉssÉÏUxÉærÉÑï£Çü
qÉåbÉlÉÉS mÉÑlÉlÉïuÉæÈ ll
aÉÉåqÉÔ§ÉÌmÉmmÉsÉÏrÉÑ£Çü
qɱïÇ ÂSèkuÉÉ mÉÑOåûssÉbÉÑ
l
ÍsɽÉiÉç ¤ÉÉæSìæÈ UxÉÉå
UÉæSìÉå
30/07/09
Rasoushadhis and bhasmas used
in Arbuda
48
AoÉÑïSWûUÉå UxÉ

iÉhQÒûsÉÏrÉMüuÉwÉÉïpÉÔlÉÉaÉMülrÉÉ
oÉsÉÉUxÉå l
aÉÉåqÉÔ§ÉÇ cÉ UxÉÈ ÌmɹÈ
mÉÑOûmÉYuÉÉåÅoÉÑïSÉÌSÎeÉiÉç ll

( U. U. xÉ.
24/136 )
Rasoushadhis and bhasmas used
30/07/09 49
in Arbuda
ApÉëMü pÉxqÉ
• Puta – 1 – 1000 ( AÍkÉMüxrÉÉÍkÉMÇü
TüsÉqÉç )

• aÉÉæUÏiÉåeÉÈ mÉUqÉqÉqÉ×iÉÇ
uÉÉiÉÌmɨɤÉrÉblÉÇ
mÉëblÉÉoÉÉåÍkÉ mÉëzÉÍqÉiÉÂeÉÇ
uÉ×wrÉqÉÉrÉÑwrÉqÉaêrÉqÉç

• oÉsrÉÇ ÎxlÉakÉÇ ÂÍcÉSqÉMüTÇü


30/07/09
Rasoushadhis and bhasmas used
50
in Arbuda
• xÉuÉïurÉÉÍkÉWûUÇ Ì§ÉSÉåwÉzÉqÉlÉÇ
uÉ»åû¶É xÉlSÏmÉlÉÇ....
....xÉ±È mÉëÉhÉÌuÉuÉkÉïlÉÇ .....( U.
mÉë. xÉÑ. )

• qÉ×irÉÉåpÉÏïÌiÉ WûUÌiÉ xÉiÉiÉÇ


xÉåurÉqÉÉlÉÇ qÉ×iÉÉpÉëMüqÉç
( AÉ. mÉë)

• xÉuÉïUÉåaÉWûUÇ urÉÉåqÉ eÉÉrÉiÉå


rÉÉåaÉuÉÉWûMüqÉç ( U. ÍcÉÇ)
30/07/09
Rasoushadhis and bhasmas used
in Arbuda
51
zÉÇZÉÌuÉwÉ pÉxqÉ
• MüTüuÉÉiÉÉqÉrÉWûUÉå , oÉsrÉ ,
uÉ×wrÉ , UxÉÉrÉlÉ -( UxÉÉqÉ×iÉ )

• UxÉoÉlkÉMüU , ÎxlÉakÉ , SÉåwÉblÉÉå


, UxÉuÉÏrÉïM×üiÉç
( U. U. xÉ. 3/
126)
Rasoushadhis and bhasmas used
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in Arbuda
iÉÑijÉ pÉxqÉ

• sÉåZÉlÉ, pÉåSlÉ, UxÉÉrÉlÉ, oÉsrÉ,


cɤÉÑwrÉ, qÉåWûqÉåSÉåWûUÇ
mÉUÇ

• xÉÇMüÉãcÉlÉMüUÇ lÉÉQûÏlÉÉÇ
oÉsÉM×üiÉç mÉUqÉç

( U. iÉ. 21/129 )
Rasoushadhis and bhasmas used
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in Arbuda
WûÏUMü pÉxqÉ
• AÉrÉÑwrÉmÉëSqÉç
SÉåwɧÉrÉmÉëzÉqÉlÉÇ
xÉMüsÉÉqÉrÉblÉqÉç xÉÔiÉålSìoÉlkÉ
qÉ×irÉÑleÉrÉÇ AqÉ×iÉÉåmÉqÉqÉåuÉ
uÉeÉëÇ ( U. U. xÉ. 4/32 )

• xÉÑqÉ×iÉÇ
WûÏUMÇü....wÉQíûxÉÉÎluÉiÉqÉç
rÉÉåaÉuÉÉÌWû.... xÉuÉÉåïi¢×ü¹Ç
UxÉÉrÉlÉqÉç
....qÉåWûqÉåSÉåÌuÉlÉÉzÉlÉqÉç...
30/07/09
Rasoushadhis and bhasmas used
in Arbuda
54
xÉÑuÉhÉï pÉxqÉ
• UxÉ - qÉkÉÑU MüwÉÉrÉ ÌiÉ£ü
• uÉÏrÉï - zÉÏiÉ
• ÌuÉmÉÉMü - qÉkÉÑU
• aÉÑhÉ - xÉëÇxÉlÉ , aÉÑ , sÉåZÉlÉ ,
rÉÉåaÉuÉÉÌWû ,
UxÉÉrÉlÉ , ̧ÉSÉåwÉlÉÉzÉlÉÇ ,
AÉrÉÑwrÉqÉç , oÉsrÉÇ

• Dose : ¼ to ½ ratti

30/07/09
in Arbuda ( AÉ. Mü. 2/48
Rasoushadhis and bhasmas used
55
iÉÉqÉë pÉxqÉ
• UxÉ - ÌiÉ£ü MüwÉÉrÉ
• uÉÏrÉï - EwhÉ
• ÌuÉmÉÉMü - qÉkÉÑU
• aÉÑhÉ - sÉåZÉlÉ, ÌmɨÉ
MüTüÉmÉWÇû
• UÉåaÉblÉiÉÉ - SÒlÉÉïqÉ, ¤ÉrÉ,
mÉÉhQÒû, MÑü¸,

30/07/09
in Arbuda
(U. U. xÉ.
Rasoushadhis and bhasmas used
56
Maggotification
• Paste of Nishpava, Pinyaka, Kulatha,
Mamsa, Takra etc. are applied over
arbuda to attract flies. So that worms
& parasites may be produced and
will consume the tissues of Arbuda.
( Su. Chi. 18 / 37-39 )
• Remnant unconsumed Arbuda should
be done Lekhana & Agnikarma. 

Rasoushadhis and bhasmas used


30/07/09 57
in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
Rasoushadhis and bhasmas used
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in Arbuda
Effect of rasayana :-

• It effects the genesis of proper


rasadi dhatus

• It acts as an immuno-modulator

• It acts at the physical and mental


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Rasoushadhis and bhasmas used
62
in Arbuda
Some important Rasayana
prayogas
 Bhallataka rasayana
 Chitraka rasayana
 Silajatu rasayana
 Lashuna rasayana
 Pippali rasayana
 Hareetaki rasayana
 Guggulu rasayana
Rasoushadhis and bhasmas used
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in Arbuda
Drugs having anti cancerous
action
 Aswagandha Vinca
rosea

Ananthamool  Lashuna
a
 Silajatu
 Amalaki
 Guggulu
 Triphala
 Kumari
 Guduchi
 Chitraka
 Bhallataka
 Yavani
 Haridra Rasoushadhis and bhasmas used
30/07/09 64
in Arbuda
Discussion
• Can we manage Arbuda without
surgery, only on Rasoushadhis ?

Rasoushadhis and bhasmas used


30/07/09 65
in Arbuda
Conclusion
• Understanding the samprapti of
Arbuda is prime requirement for
planning the treatment

• Granthi – Arbuda are Chedya Vyadhi.


So Surgery is the best line of
treatment

• Chemotherapy and Radiation therapy


cause lot of side effects. So
Rasayana therapy should be adjoined
30/07/09
Rasoushadhis and bhasmas used
in Arbuda
66
Rasoushadhis and bhasmas used
30/07/09 67
in Arbuda
References
• A. P. I. Text book of Medicine
• Sushruta Samhita
• Charaka Samhita
• Rasa Ratna Samuchaya
• Rasa Tarangini
• Yogaratnakara
• Bruhannighantu Ratnakara
• Rasendra Sara Sangraha
• Dr. Pradeep Shinde sir’s collection of
PPT
• Jamnagar dissertation
• Internet
Rasoushadhis and bhasmas used
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in Arbuda