Neelesh Bhandari
M.B.B.S (AFMC), M.D. (Path)
P.G.P in Human Rights.
Early pregnancy detection allows
3. Laboratory evaluation
5. Ultrasonography
Early Physical signs of pregnancy
• Blue discoloration of the cervix and vagina (
Chadwick's sign)
• Nausea
• Urinary frequency
Laboratory Investigations
(3) radioimmunoassay,
(9) fluoroimmunoassay.
Radioimmunoassay
Sensitivity - 5 mIU/mL
Time to complete - 4 hours
Postconception age when first positive - 10-18 days
Gestational age when first positive - 3-4 weeks
Fluoroimmunoassay
Sensitivity - 1 mIU/mL
Time to complete - 2-3 hours
Postconception age when first positive - 14-17 days
Gestational age when first positive - 3.5 weeks
Failure to achieve the projected rate of rise
(slow rise) may suggest an ectopic
pregnancy or spontaneous abortion.