Diseases Of Salivary Glands Lab

This histological section is taken from one of the major salivary glands 1- What is the type of Acini present?! 2- What is the most likely gland?! 3- Through what duct this gland drains its saliva into the oral cavity?!

This histological section is taken from one of the major salivary glands 1- What is the type of Acini present?! 2- What is the most likely gland?! 3- Through what duct this gland drains its saliva into the oral cavity?!

This histological section is taken from one of the major salivary glands 1- What is the type of Acini present?! 2- What is the most likely gland?! 3- Through what duct this gland drains its saliva into the oral cavity?!

These clinical pictures show the various locations of minor salivary glands in the oral cavity 1- What is the type of Acini present?!

2- Name three different locations where such glands cant be found?!

This 50 years old female is presented to the clinic for routine dental examination Upon examination, unilateral mildly tender swelling of the submandibular gland region is found This is the result of the biopsy done!
1- What is the most likely diagnosis?! 2- What is the main cause behind such condition?! 3- What in the history of the patient might confirm diagnosis?! 4- Of the major salivary glands, which is more commonly involved?!

5- Whats the best tool to diagnose duct obstruction and glandular tissue destruction in this condition?!

Give me 3 differential diagnoses for this histological appearance!!

This histological section from one of the major salivary glands was sent to you to reach definitive diagnosis
1- Describe this histological appearance?! 2- What is the most likely diagnosis?! 3- What is the main cause behind such condition?! 4- What is the structure represented by the circle?!

This 45 years old female is presented to the clinic for routine dental examination Upon examination, bilateral painless swelling of the parotid gland region is found This is the result of the biopsy done!
1- What is the most likely diagnosis?! 2- What causes this condition?! 3- Of the salivary glands, which are more commonly involved?! 4- When lacrimal glands are also involved, then the condition is?!

Non-caseating granuloma (macrophages)

Sarcoidosis

Lymphocytes

This 30 years old female is presented to the clinic for routine dental examination Upon examination, this yellowish discoloration of the orifice of Wharton's duct was noticed This is the result of the biopsy done!
1- What is the most likely diagnosis?! 2- Of the salivary glands, which are more commonly involved?! 3- What are the clinical features of this condition?!

Sialolith Hyperplastic ductal epithelium

Salivary Calculus (Sialolith)

This 30 years old male is presented to the clinic for consultation Upon examination, two deep crater-like ulcers were found on the hard palate The patient states that these ulcers were just a swelling one week ago This is the result of the biopsy done!
1- What is the most likely diagnosis?! 2- What causes this condition?! 3- What is the clinical and histological differential diagnosis for such ulcers?!?! 4- Whats your management?!

Lobular Necrosis

Sequamous Metaplasia

Necrotizing Sialometaplasia

May start as indurated swelling

May start as small ulcer

Necrotizing Sialometaplasia

This 65 years old male is presented to the clinic for consultation Upon examination, oral tissues looked dry, smooth and glazed and the tongue looked atrophic, fissured and Lobulated Patient complains from dry gritty eyes
1- What is the cause of this intraoral finding?! 2- What is the cause of this ophthalmic finding?! 3- What is the most likely diagnosis?!

This 65 years old male is presented to the clinic for consultation Upon examination, oral tissues looked dry, smooth and glazed and the tongue looked atrophic, fissured and Lobulated Patient complains from dry gritty eyes
1- Into how many categories this condition is classified?! 2- If this patient has rheumatoid arthritis, then to what category you can relate him?!

3- What are the components of the European criteria to reach the final diagnosis?!

This 65 years old male is presented to the clinic for consultation Upon examination, oral tissues looked dry, smooth and glazed and the tongue looked atrophic, fissured and Lobulated Patient complains from dry gritty eyes
1- Whom are mainly affected: males or females?! 2- Into which category, oral and ocular symptoms are more severe?! 3- What are the most important histological features seen?! 4- What are the most important investigatory methods?!

5- What is the most important complication?!

Lymphocytic infiltration Sjgren syndrome

Sjgren syndrome

Snowstorm or cherry tree in blossom

Sjgren syndrome

This 40 years old male is presented to the clinic for consultation Upon examination, Slowly growing, painless, rubbery swelling with intact overlying skin or mucosa is present Patient is aware of lesion for several years This is the result for the biopsy done!
1- What is the most likely diagnosis?!

2- Of the salivary glands, which is more commonly involved?!?!

3- What are the most important histological features seen?!

4- What is the best treatment option and why?!

Pleomorphic adenoma

Pleomorphic adenoma

Hyalinization

Chondroid
Pleomorphic adenoma

Keratin pearl Pleomorphic adenoma

This 50 years old male is presented to the clinic for consultation Upon examination, Slowly growing, painless, rubbery swelling is present Patient is aware of lesion for several years This is the result for the biopsy done!
1- What is the most likely diagnosis?! 2- What are the most important histological features seen?!

Warthin Tumor

These histological sections were sent to you to reach final diagnosis

1- What is the most likely diagnosis?! 2- What are the most important histological features seen?!

This histological section was sent to you to reach final diagnosis

1- What is the most likely diagnosis?! 2- What are the most important histological features seen?!

Canalicular adenoma

This 30 years old male is presented to the clinic for consultation Upon examination, Slowly growing, painless, rubbery swelling with intact overlying skin or mucosa is present
1- Give me 2 clinical differential diagnoses?! 2- According to the histological features, what is the most likely diagnosis?! 2- Of the salivary glands, which is more commonly involved?!?! 3- What are the most important histological features seen?! 4- What are the characteristic features of low and high grade variants of the condition?!

Intermediate cells

Mucous cells

Epidermoid cells

Mucoepidermoid carcinoma

Low grade Mucoepidermoid carcinoma

High grade Mucoepidermoid carcinoma

Differentiation between High grade Mucoepidermoid carcinoma and Sequamous cell carcinoma through PAS stain

This 30 years old male is presented to the clinic for consultation Upon examination, this oral ulceration is seen
1- Give me 3 clinical differential diagnoses?!

2- According to the histological features, what is the most likely diagnosis?!

These histological sections were sent to you to reach final diagnosis The patient is present with facial palsy and neurological manifestations
1- What is the most likely diagnosis?!

2- What are the most important histological features seen?!

3- Is radiotherapy an acceptable treatment?! 4- Which carry better prognosis: cribriform or solid types?!