15/04/09
Acute
- intensely pruritic, erythematous papules and
vesicles scratching that results in excoriations
and exudates
Subacute
- thicker, paler, scaly, erythematous, and excoriated
plaques
Chronic
- thickened plaques, lichenification and fibrotic
papules
Clinical Features
Potency
Potency Drugs
Low Hydrocortisone 1%
Moderate Betamethasone valerate 0.01-0.05%
Clobetasone butyrate 0.05%
High Betamethasone valerate 0.1%
Mometasone furoate 0.05%
Very high Clobetasol propionate 0.05%
Topical Corticosteroids
Systemic corticosteroids
- e.g. prednisolone
- short course to control severe flare
Cyclosporine
- severe, recalcitrant
- adults: 5mg/kg
- childrens: 3mg/kg
References
Adams VR, Yee GC. Lymphoma. In: Dipiro JT, Talbert RL, Yee
GC, et al. Pharmacotherapy: a pathophysiologic approach. 6th
edition. New York: McGraw-Hill; 2006. Chapter 97 pg 1785-91
Koda-Kimble MA. Applied therapeutics: the clinical use of
drugs. 8thedition. USA: Lippincott Williams &Wilkins; 2005.
Chapter 38: pg 1-18
Austrlian Medicines Handbook, 2009
Guidelines for the management of atopic eczema. Primary
Care Dermatology Society & British Association of
Dermatologist. 28, 2006