This PowerPoint file contains a number of slides that may be useful for teaching of
genetics concepts.
You may use these slides and their contents for non-commercial educational purposes.
DMD Pedigree
The X chromosome carrying the disease-causing mutation can be tracked through the family. Note: Shaded
squares = affected males: dots in circles = carrier females.
A muscle biopsy from a female carrier of Duchenne muscular dystrophy stained with
an antibody against dystrophin
Note the patchy distribution of staining around the outer membranes of cells (compare with the sections from
an affected boy and a normal control in next slide).
Dystrophin
antibody staining of
muscle cells
Normal Control
Reaction 2
3
NC 1
Reaction 3
3
NC
Rachel
14.3.74
Tony
26.9.73
Susie
3.6.95
Fay
7.1.98
Jason
15.11.99