PROPERTIES OF VIRUSES
1. Virus structure consist of : Nucleic acid ,
capsomer / capsid and envelope
2. Genome can be either DNA or RNA
3. Viruses do not have ribosome
4. Viruses do not replicate by binary fission
5. Viruses range from 18 nm to 300 nm
in diameter.
8. No sensitivity to antibiotics
9. Can not grow on artificial media.
Division by
binary fission
Whether they
have both DNA
and RNA
Whether
they have
ribosomes
Their
sensitivity to
antibiotics
Bacteria
Mycoplasma
Rickettsia
Chlamydia
Viruses
* The arenavirus family (an RNA virus family) appears to package ribosomes 'accidentally'. The packaged ribosomes
appear to play no role in viral protein synthesis.
STABILITY OF VIRUSES
- Stable when added MgCl2, MgSO4,Na2SO4
- Stable is important for preparing vaccine.
PH 5.00 -9,00
- When exposed to ultra violet lamp loss
activity.
Sugar-phosphate
backbone
Nucleotides
Gbr 3.
DNA double helix
NAKED ICOSAHEDRAL
NAKED HELICAL
Nucleic acid
- nonsegmented or segmented
- linear or circular
- if genome is single stranded RNA, can
it function as mRNA?
- whether genome is diploid (it is in
retroviruses)
- symmetry (icosahedral, helical,
Virion structure
complex)
- enveloped or not
- number of capsomers
GLOSSARY :
1. Capsid : The protein coat that surrounds the
Muh.Asaad Maidin
Glucoprotein virus
Attached to receptor CD4
& co-receptor of sel T
T-Lymphocyte
Muh.Asaad Maidin
Penetration and
uncoating
T-Lymphocyte
References ;
1. Cohen,J., Powderly,W.G.,et al, 2004.
Infectious Diseases, 3 rd edith. Mosby.
2. Levinson, W., and Jawetz, E., 2002 Medical
Microbiology, a Lange medical book, seventh edith.
3. Metseelar, D., and Simpson,D.I.H.,1982.
Practical virology, For Medical Students and
Practisioners in Tropical Countries, Oxford Univ.Press.
4. Mims,C.,Dockrell,H.M, et al, 2004.
Medical Microbiology, 3rd edith.Elsevier Mosby.
5. Virella, G., 1997. Microbiology and Infetious Diseases,
3rd edition,William & Wilkins a waverly company.
6. Internet.