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Mechanical Ventilation I

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Objectives

Describe types of breaths and modes of


mechanical ventilation
Describe interactions between ventilatory
parameters and modifications needed to
avoid harmful effects

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Indications for
Mechanical Ventilation

Ventilation abnormalities
Respiratory muscle dysfunction
Respiratory muscle fatigue
Chest wall abnormalities
Neuromuscular disease

Decreased ventilatory drive


Increased airway resistance and/or
obstruction
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Indications for
Mechanical Ventilation

Oxygenation abnormalities
Refractory hypoxemia

Need for positive end-expiratory


pressure (PEEP)
Excessive work of breathing

MVA

Types of Ventilator Breaths

Volume-cycled breath
Volume breath
Preset tidal volume

Time-cycled breath
Pressure control breath
Constant pressure for preset time

Flow-cycled breath
Pressure support breath
Constant pressure during inspiration
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Modes of Mechanical
Ventilation

Consider trial of NPPV


Determine patient needs
Goals of mechanical ventilation
Adequate ventilation and oxygenation
Decreased work of breathing
Patient comfort and synchrony

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Modes of Mechanical Ventilation


Point of Reference:
Spontaneous Ventilation

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Continuous Positive Airway


Pressure (CPAP)

No machine breaths delivered

Allows spontaneous breathing at elevated


baseline pressure
Patient controls rate and tidal volume

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Assist-Control Ventilation

Volume or time-cycled breaths + minimal ventilator


rate
Additional breaths delivered with inspiratory effort
Advantages: reduced work of breathing; allows
patient to modify minute ventilation
Disadvantages: potential adverse hemodynamic
effects or inappropriate hyperventilation

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Pressure-Support Ventilation

Pressure assist during spontaneous inspiration


with flow-cycled breath
Pressure assist continues until inspiratory effort
decreases
Delivered tidal volume dependent on inspiratory
effort and resistance/compliance of lung/thorax

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Pressure-Support Ventilation

Potential advantages

Patient comfort
Decreased work of breathing
May enhance patient-ventilator synchrony
Used with SIMV to support spontaneous breaths

MVA

Pressure-Support
Ventilation

Potential disadvantages
Variable tidal volume if pulmonary
resistance/compliance changes rapidly
If sole mode of ventilation, apnea alarm mode
may be only backup
Gas leak from circuit may interfere with cycling

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Synchronized Intermittent
Mandatory Ventilation (SIMV)

Volume or time-cycled breaths at a preset


rate
Additional spontaneous breaths at tidal
volume and rate determined by patient
Used with pressure support

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Synchronized Intermittent
Mandatory Ventilation
(SIMV)

Potential advantages

More comfortable for some patients


Less hemodynamic effects

Potential disadvantages
Increased work of breathing

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Controlled Mechanical
Ventilation

Preset rate with volume or time-cycled breaths


No patient interaction with ventilator
Advantages: rests muscles of respiration
Disadvantages: requires sedation/neuro-muscular
blockade, potential adverse hemodynamic effects

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Inspiratory Plateau Pressure


(IPP)

Airway pressure measured at end of inspiration with


no gas flow present
Estimates alveolar pressure at end-inspiration
Indirect indicator of alveolar distension
PIP
Plateau pressure

Inspiration

Peak pressure

Expiration
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Plateau pressure

Inspiratory Plateau Pressure

High inspiratory plateau pressure


Barotrauma
Volutrauma
Decreased cardiac output

Methods to decrease IPP


Decrease PEEP
Decrease tidal volume

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Inspiratory Time: Expiratory


Time Relationship (I:E ratio)

Spontaneous breathing I:E = 1:2


Inspiratory time determinants with volume
breaths

Tidal volume
Gas flow rate
Respiratory rate
Inspiratory pause

Expiratory time passively determined


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I:E Ratio during Mechanical


Ventilation

Expiratory time too short for exhalation


Breath stacking
Auto-PEEP

Reduce auto-PEEP by shortening


inspiratory time
Decrease respiratory rate
Decrease tidal volume
Increase gas flow rate
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Auto-PEEP

Can be measured on some ventilators


Increases peak, plateau, and mean airway
pressures
Potential harmful physiologic effects

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Auto-PEEP

Can be measured on some ventilators


Increases peak, plateau, and mean airway
pressures
Potential harmful physiologic effects

MVA

Key Points

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