Subtopics
Terms/Definitions
Physiology of Emesis
Approach
Evaluation
Disease based
References
Others essential reading
Terms
Vomit:
Forced ORAL expulsion of GI content
Contraction of abdominal and chest wall
Nausea:
Unpleasant sensation on the need to
vomit/imminent vomitting
Vomit
Nausea
Nausea>Vomit
Physiology
1. Neurological Pathway
vagal afferents (1), the area postrema
*CTZ* (2), the vestibular system (3), and
the amygdala (4)
2. Neurotransmitter
1)5-HT3
2)M1, D2, 5-HT3, NK-1
3)H1
4)M1, D2, H1, 5-HT3, NK-1 +
Emotion/olfactory
APPROACH
History
Physical
Examination
Investigations
Diagnosis
Targeted
treatment
Aetiolgy
1)
2)
3)
4)
Diagnosis
Differential Diagnosis
Risk Factors
Complications
1) -hydration assessment
RED FLAGS
1)Nonspecific symptoms
(severity)
2) Surgical GIT (obstruction)
3) Neurologic/Systemic (raised
ICP, recurrent)
Complication
Treatment
EVALUATION
Concerning Signs
History and Physical Examination
Investigations
History
Vomit vs regurgitation (presence of effort)
Triggers?(lactose/fructose/onset minutesto hours of
food intake+ cutaneous+ respiratory symptoms)
Projectile/absence of nausea
Periodic episodes? (IEM, migraine, cyclic)
Time (early morning+positional triggers)
Duration
Infective cause (contacts, febrile, associated diarrhea)
Content-billious/blood/undigested/feculent/surgical
cause of vomitting.
Determinant for intervention.
Physical examination
General examination
Well vs toxic, signs of dehydration,
Abdominal examination
Pain, Distension , Vomiting, Obstipation
Visible bowel loops/absent vs borborygmi
Surgical cause by tenderness site (appendix, gall bladder,
pancreas, renal, epigastric)
organomegaly
Neurologic examination
Conscious level (CNS lesion, IEM, toxic, severe dehydration)
Raised ICP signs/ localizing signs
Others
Unusual odour, enlarged parotids, abnormal external genitalia
Laboratory
investigations
Hydration assessment
No clinically detectable dehydration
(<5% loss of body weight)
Clinical dehydration (5-10%)
Shock (>10%)
Mnemonic ( Head (4)/ Thorax (4)/
Limbs (4)/ Genitalia (1) = 13 signs
4 in the Head
4 in the thorax
Skin color
Breathing rate (tachypnea)
Tissue turgor
Weight*
4 in the limbs
Cold peripheries
Capillary refill time
Increase pulse rate (tachycardia)/
weak pulse
Blood poressure (hypotension in
decompensated shocl)
Those in red is at risk of progression
to shock
GERD
is a normal physiologic process
occurring several times per day in
healthy infants, children, and adults.
Last <3 minutes, occur in the
postprandial period, and cause few or
no symptoms.
GERD is present when the reflux of
gastric contents causes troublesome
symptoms and/or complications
Pyloric stenosis
Intussusception
vast majority of intussusceptions
occur in children (95%), usually after
the first three months of life
no lead point can usually be
identified (90%) and this most
frequently thought to relate to
enlarged lymphoid tissue following
an infection
Plain film
References
Nelson textbook of pediatric 19th Edition
Illustrated textbook of pediatric, Sunflower 4th edition
Website
Uptodate.com on Approach to the infant or child with nausea and
vomiting http://
www.uptodate.com/contents/approach-to-the-infant-or-child-with-na
usea-and-vomiting
Infantile hypertrophic pyloric stenosis
Acid reflux (gastroesophageal reflux) in infants
Empem.org Emergency Medicine and Paediatric Emergency Medicine
Radiopedia.org on intussusception
AGE
NEC
Hirschprung
Volvolus
Inborn errors of metabolism
Whooping cough
Strangulated hernia
Coeliac disease
Testicular torsion