Briones
Djamaekha Dee A. Jaylo
An understanding of the effects of halogenation
has been useful in the important area of drug
design
cortisol
In order to be effective a drug must be designed to
reach its site of action. In many cases, this
involves penetration of one or more membrane
barriers between the site of application and the
receptor location.
Because the cell membrane is a lipid bilayer with a
nonpolar interior, it tends to resist penetration by
molecules that are not fat soluble; the more lipid
soluble a molecule is, the better it will diffuse
across the membrane. Such lipid solubility can
sometimes be increased by halogen substitution.
Molecule Cortisol
- a corticosteroid hormone secreted by the
adrenal cortex.
Biological Functions :
- Helps regulate carbohydrate and protein
metabolism and salt balance.
- Inhibit inflammation.
Danica Rose P. Macaraya
Cheyenne Christine M. Villamor
The alcohol is absorbed through the membranes in a
person's mouth, throat, stomach, and intestines. Once
absorbed by the body, the alcohol passes immediately into
the bloodstream, where it circulates until it is expelled
through evaporation in the lungs. Evaporation occurs
because alcohol is "volatile" in a solution, meaning that its
molecules do not combine with the liquid that it mixes with.
Due to this volatility, as the blood passes through
Breathalyzer Test
Na2Cr2O7 H+
Cyclohexanol Cyclohexanone
Pyridinium chlorochromate (PCC)
PCC
Hexanol Hexanal