AGE
VACCINES
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Birth
BCG
OPV 0
Hep-B 1
6 weeks
DTwP 1/DTaP 1
IPV 1
Hep-B 2
Hib 1
Rotavirus 1
PCV 1
10 weeks
DTwP 2/DTaP 2
IPV 2
Hib 2
Rotavirus 2
PCV 2
14 weeks
DTwP 3/DTaP 3
IPV 3
Hib 3
Rotavirus 3
PCV 3
6 months
OPV 1
Hep-B 3
9 months
OPV 2
Measles
12 months
Hep-A 1
For both killed and live hepatitis-A vaccines, 2 doses are recommended
15 months
MMR 1
Varicella 1
PCV booster
16 to 18 months
DTwP B1/DTaP B1
IPV B1
Hib B1
18 months
Hep-A 2
2 years
Typhoid 1
4 to 5 years
DTwP B2/DTaP B2
OPV 3
MMR 2
Varicella 2
Typhoid 2
MMR: the 2nd dose can be given at anytime 4-8 weeks after
the 1st dose.
Varicella: the 2nd dose can be given at anytime 3 months after
the 1st dose
10 to 12 years
Tdap/Td
HPV
BCG
Live attenuated
Intradermal
Danish 1331 strain for vaccine
production
Freeze dried
DPT
Park Williams 8
Diphtheria toxoid 24 Lf, Tetanus toxoid 5
Lf pertussis 20,000 million killed bacteria
6, 10, 14 weeks.. Boosters at 1.5 years
and 4-5 years
Deep IM anterolateral aspect of thigh
Contra in neurological disease,
convulsions
but acellular pertussis vaccine is ok
OPV - Sabin
Vaccine associated paralytic polio 1
in 3 million
MgCl 2
Vaccine vial monitor indicate
potency of vaccine
Least stable vaccine
Lansing, Leon and Brunhilde
MMR
Live attenuated
Measles- Schwartz chick embryo cells
Mumps Urabe AM-9 - embryonic hen egg
Rubella- Wistar RA/ 3M human diploid
cells
Measles
HPV
Gardasil (quadrivalent 16, 18, 6, 11),
Cervarix (16, 18)
Aluminium adjuvant present
Rota virus
Rotarix, Rotateq
Chances of intussusception if given
later.
Pneumococcal vaccine
PC 7
6, 10, 14 weeks
1 booster at 15-18 months
After 2 years PPV 23 polysaccharide vaccine
can be given
Indications HIV, Chronic pulmonary disease,
sickle cell disease, CSF leak, cochlear
implants, nephrotic syndrome in remission
strains
Children on corticosteroids
>2mg/kg/day for 14 days should
not receive live virus vaccine until
steroids discontinued for 1 month
Varicella
Varicella (optional) one dose at 1213 years;
Or 2 doses > 13 years
Takahashi developed it from oka
strain
Hib
H influenza b capsular
polysaccharide
PRP-T and PRP-CRM 197 conjugate
Hib vaccine in india
JE
Nakayama strain
Not an outbreak response vaccine
Epidemiologic shift
This refers to an upward shift in age of
infection/disease in communities with partial
immunization coverage. Owing to vaccination,
the natural circulation of the pathogen
decreases and the age of acquisition of
infection advances. This is especially
important for diseases like rubella, varicella
and hepatitis A, wherein severity of
disease worsens with advancing age.
1. BCG Vaccine
Should be given at birth or at first contact Catch up may be given up to 5
years
3. Poliovirus vaccines
OPV in place of IPV If IPV is
unaffordable/unavailable, minimum 3 doses
Additional doses of OPV on all SIAs IPV:
Minimum age: 6 weeks IPV: 2 instead of 3
doses can be also used if primary
series started at 8 weeks and the interval
between the doses is kept 8 weeks IPV
catch-up schedule: 2 doses at 2 months
apart followed by a booster after 6 months