Nama :

Syarifuddin Rauf

Jabatan : 1. Kepala Bagian Ilmu Kesehatan

Anak
Fak.Kedokteran UNHAS

2. Koordinator Sistim Urogenitalia

3. Dosen Pengampu Sistim
Bioetik,Humaniora
HAM
4. Dosen Pengampu Sistim

IMMUNIZATION
Syarifuddin Rauf
Bagian Ilmu Kesehatan
Anak
FKUH RSU Dr
WahidinSudirohusodo

Immunization background in
Indonesia
Population : 220 juta
Children : < 18 tahun : 37,5 % : 82,5 juta
Under 5 : 10,4 % : 22,8 juta
Infant Mortality Rate :
142 / 1000 (1971) 112 / 1000 (1980)
71 / 1000 (1985) 54 / 1000 (1990)
40 / 1000 (2001)

30,8/1000(2004)26,6/1000(2007)
DUE TO IMMUNIZATION

IMMUNIZATION RECOMMENDATIONS

1.CHILDREN
2.ADOLESCENTS
3.ADULTS
4.HEALTHCARE WORKERS
5.TRAVELING
6.PREGNANCY
7.IMMUNECOMPROMIZED PATIENTS
8.CHILDREN UNDERGOING TRANSPLANTATION

Immunization
Passive :the administration of
preformed antibody
Active : antigen is administered to
mimic natural infection
Active immunization = Vaccination
Vaccin : A changed microorganism or
toxoid which cause disappearance of
pathogenicity/toxicity but still retain
antigenicity

ACTIVE IMMUNIZATION
SEVERAL TYPE OF VACCINES :
1. ATTENUATED LIVE VACCINES:
Consist of entire/partial microorganism
(virus or bacteria)which is subjected to
process of attenuation)
e.g. : BCG,measles,varicella
2. KILLED VACCINES :
Composed of killed organism (bacterial
or virus) e.g. cholera or Pertussis

 3.SUBUNIT VACCINES :
Comprised of a constituent of the
whole organism such as viral protein.
e.g. Hepatitis B surface antigen
4.TOXOID VACCINES :
Nontoxic toxin but retain the ability
to stimulate the production of
antibody
5.RECOMBINANT VACCINES :
When one or more gens encoding
for critical
determinants from

PASSIVE IMMUNITY
Antibody from mother was
transferred passing the placenta in
third trimester
Example : Giving tetanus toxoid to
pregnant woman may cause
decreasing of neonatal tetanus
morbidity

RECOMMENDED IMMUNIZATION SCHEDULE

(PROGRAM PENGEMBANGAN IMUNISASI)
NO

TYPE OF

DISEASES/COMPLICATION

VACCINE
1

BCG

TBC Paru, TBC Kelenjar, TBC Otak

(Meningitis TB)

HEPATITIS

Hepatitis, Sirosis Hati, Kanker Hati

(Hepatoma)

POLIO

Polio Mielitis (Lumpuh Layu)

DPT

Difteri, Pertusis, Tetanus

MEASLES

MEASLES(Morbili, Serampa)

RECOMMENDED SCHEDULE IMMUNIZATION IN COMMUNITY

AGE

VACCINES

SERVICE

0 bulan
1 bulan

HB 1
BCG, Polio 1

Rumah posyandu
Posyandu *

2 bulan

DPT/HB Kombo 1, Polio 2

Posyandu *

3 bulan

DPT/HB Kombo 2, Polio 3

Posyandu *

4 bulan

DPT/HB Kombo 3, Polio 4

Posyandu *

9 bulan

Campak

Posyandu *

BABY BORN IN HOSPITAL/MIDWIVES SERVICE

0 bulan
HB 1, Polio 1, BCG
2 bulan
DPT/HB Kombo 1, Polio 2

RS / RB / Bidan
RS / RB / Bidan

3 bulan

DPT/HB Kombo 2, Polio 3

RS / RB / Bidan

4 bulan

DPT/HB Kombo 3, Polio 4

RS / RB / Bidan

9 bulan

Campak

RS / RB / Bidan

Keterangan :
*

: Atau tempat pelayanan lain

: Atau posyandu

ANTIBODY

Jan

Feb

Ma
r

Apr

DPT I
2mt

Mei

Jun

II
3mt

Jul

III
4mt

Agu
s

Sep
t

Okt

No
v

Des

LOCATION OF
INJECTION

12/7/15

Komnas PP KIPI

NO CONTRAINDICATION
1.RUNNING NOSE
2.SLIGHT FEVER( < 37,8 C)
3.COMMON COLD
4.RECEIVING ANTIBIOTICS
5.BREASTFEEDING
6.SLIGHT DIARRHEA

CONTRAINDICATION

1. ANAPHYLAXIS REACTION

2.HIGH FEVER

3.CRYING LASTING FOR 3 HOURS OR MORE

4.A DOCUMENTED HISTORY OF CONVULSION/EPILEPSY

5.IMMUNODEFICIENCY DISEASES
( HIV, CANCER)

BCG

MENINGITIS
TBC

DTP
BASIC IMM. :
3 X (2,3,4 OR 2,4,6 months)
Booster :

- 18-24 month
5-7 year
12 year

Hepatitis B
Prevent : hepatitis B
Hepatitis B vaccine :
Plasm derivative
Recombinant

Measles vaccine
Live attenuated virus
Age : 9 month
Dose : 0.5 ml SC.
Booster : Age : 5-7 year

Polio vaccine
Prevent :poliomyelitis
Flaccid paralysis (Lumpuh layu),
Polio vaccine :
Attenuated live vaccine(Sabin) : oral
Killed vaccine(Salk) : parenteral

Non PPI vaccines

Hib
MMR
Typhoid
Hepatitis A
Varicella
Influenzae
Pneumococcus
Rotarix
Cervarix

Thank You