Genitalia IV
Ovary
Ovary
Inflammation
Non-neoplastic
cysts
Neoplasms
Ovary
Inflammation
Primary
inflammation is
rare
Usually secondary to
spread from fallopian
tube (tubo-ovarian
abscess)
Other causesappendicitis,
Ovary
Non-neoplastic cysts
Follicular
cysts - Polycystic
Ovarian Syndrome (SteinLeventhal)
Corpus luteum cysts - may
cause intraperitoneal
haemorrhage
Simple cysts
Endometriotic cysts haemorrhage within
Ovary
Neoplasms
Classification of Primary Neoplasms
Surface
65%)
Germ cells (approx. 20%)
Sex cord-stromal cells (approx. 10%)
Miscellaneous, i.e. tumours
not specific to the ovary
(approx. 5%)
Surface Epithelial
Neoplasms
Classification
Serous
Mucinous
Endometrioid
Brenner
Clear
cell
Undifferentiated
Surface Epithelial
Neoplasms
Cystadenomas/cystadenocarci
nomas
Serous - lining resemble
fallopian tube
Mucinous - resemble lining of
cervix
Endometrioid - resemble
endometrium
Serous Tumours
25%
Less
Endometrioid
Resemble
endometrial
Sex Cord-Stromal
Tumours
Granulosa
cell
tumour
Thecoma/Fibroma
Sertoli-Leydig cell
tumour
Occur
Granulosa Cell
Tumours
at any age
Peak incidence, postmenopausal
25-75%
produce excessive
oestrogen
Children - precocious puberty
Reproductive age - menstrual
irregularities
Older age - p.m.b.
All
Thecoma/Fibromas
Originate
Thecoma
Solid, firm
May produce oestrogen; a
few produce androgens
Nearly always benign
Fibroma
Sertoli-Leydig Cell
Tumours
Resemble
All malignant
Very radiosensitive with
Up to 95% 5-yr survival
Yolk
Teratoma
Benign cystic teratoma (dermoid
cyst)
Most common GCT (up to 95% of
GCTs)
Are multilocular or unilocular
cysts
Containing cheesy or porridgelike sebaceous material with
matted hair
Sometimes cartilage, bone
and/or teeth grossly
Teratoma
Solid teratomas
Are invariably malignant
Are also known as "immature
teratomas"
Malignancy due to
immaturity of the tissues
usually immature
neuroepithelium
Secondary (Metastatic)
Tumours
Most
common - stomach,
colon, breast, corpus and
cervix uteri
Krukenberg tumour - bilateral,
solid, mucin-secreting signet
ring cells; usually from
stomach, colon, breast
Mets to ovary connote poor
prognosis
Ovarian Tumours
General Features
USA