MENGAPA STANDARISASI

BAHAN OBAT ALAM HARUS

DILAKUKAN?
TIDAK MENJUAL
SECARA EKONOMIS

BERAGAM
JENIS
SENYAWA
METABOLIT
DALAM OBAT
HERBAL

80% PENDUDUK
DUNIA
MENGGUNAKAN
OBAT HERBAL
SECARA EMPIRIS

FITOFARMA
KA

FITOFARMAK
A

sediaan obat bahan alam

yang telah dibuktikan
keamanan dan khasiatnya
secara ilmiah dengan uji
praklinik dan uji klinik,
bahan baku dan produk
jadinya telah di standarisasi.

Botani farmasi
Farmakognosi
fitokimia

farmakologi

kimia

?
ADA
APA
DEN
GAN
MU

farmaceutika

BAHAN
ALAM

OBAT TRAD
JAMU

SEDIAAN
GALENIK

?
FITO
FARM
AKA

OBAT HERBAL
TERSTANDAR

 Didunia terdapat 40.000 spesies tanaman, 30.000

berada di Indonesia, 9.600 berkhasiat obat dan sekitar
400 spesies dimanfaatkan sebagai obat tradisional
Saat ini pemanfaatan sumber daya hayati terbesar
adalah dalam memproduksi Obat
WHO (2005) : 75-80% penduduk dunia menggunakan
herbal, dan ada 3 kelompok:
1. Terintegrasi: Tiongkok, Korea, Jepang
2. Formal: Inggris: Jerman, Belanda
3. Toleran: Indonesia dan negara berkembang

 Pengobatan dan pengetahuan obat tradisional

di
Indonesia diturunkan secara lisan dari satu
generasi ke generasi dan juga tertulis dari daun
lontar dan kepustakaan Keraton.
Minat masyarakat dalam menggunakan herbal
terus meningkat berdasarkan konsep back to
nature
Pasar obat alami Indonesia terus meningkat
(2003 Rp. 2,5T ; 2005 Rp. 4T ; 2010
diperkirakan
Rp. 8T)

 Pertengahan abad XX, RRC mengembangkan sistim

pengobatan baru tipe RRC : pengobatan tradisional
(TCM) terintegrasi dengan kedokteran konvensional.
Indonesia : meneliti herbal dengan menggunakan
metode ilmiah untuk diketahui efektifitas dan
keamanannya dan juga melalui saintifikasi jamu
untuk diintegrasikan ke dalam sistim kesehatan
formal, dalam upaya promotif-preventif, kuratifrehabilitatif dan paliatif, agar diperoleh hasil yang
optimal

 Berdasarkan data empiris tentang manfaat

pengobatan herbal klasik, untuk pengobatan
yang optimal dapat dipertimbangkan
terintegrasi ke dalam pelayanan kedokteran
konvensional.
Untuk tujuan tersebut diperlukan kajian secara
ilmiah tentang farmakologi efektifitas dan
keamanan pengobatan dan obat tradisional

Sources of Natural Products

Plants (250,000 different plant species in
the world)
Insects (30 million species)
Fungi (1,5 million)
Algae (1,5 million)
Other Prokaryotics (1,5 million)
(Data From R. Verpoorte, DDT (1998), 3, 232-238)

Endogenous Microorganism (????)

Marine Organism (???)
Vertebrates and Invertebrates (??)

BADAN PENGAWAS OBAT DAN MAKANAN

(PERATURAN NOMOR : HK.00.05.41.1384 , 2 Maret 2005 )
1. Obat tradisional adalah bahan atau ramuan bahan yang berupa
bahan tumbuhan, bahan hewan, bahan mineral, sediaan sarian
(galenik) atau campuran dari bahan tersebut, yang secara turuntemurun telah digunakan untuk pengobatan berdasarkan
pengalaman.
2. Jamu adalah obat tradisional Indonesia.
3. Obat herbal terstandar adalah sediaan obat bahan alam yang
telah dibuktikan keamanan dan khasiatnya secara ilmiah dengan
uji praklinik dan bahan bakunya telah di standarisasi.
4. Fitofarmaka adalah sediaan obat bahan alam yang telah
dibuktikan keamanan dan khasiatnya secara ilmiah dengan uji
praklinik dan uji klinik, bahan baku dan produk jadinya telah di
standarisasi.
5. Sediaan galenik adalah hasil ekstraksi simplisia yang berasal dari
tumbuh-tumbuhan atau hewan.

ISSUE STRATEJIK PROBLEM BANGSA

DALAM BIDANG OBAT BAHAN ALAM
1.
2.
3.
4.
5.
6.
7.

SUMBER BAHAN BAKU

ILMU PENGETAHUAN DAN TEKNOLOGI
PENDIDIKAN
PENGEMBANGAN PRODUK
INSTRUMENTS
VALIDASI MANUFAKTUR PRODUK
PENGABDIAN (PEMBERDAYAAN)
MASYARAKAT
8. PROFESSIONALISME TENAGA
KESEHATAN
9. REGULASI PEMBINAAN
PENGAWASAN

BAHAN
OBAT

Pengembangan Obat Modern

FDA

PARADIGMA :
1.Quality
2.Safety
3.Efficacy
4.Acceptable

PRODUK
OBAT

MASYARAKAT

1.RATIONALITY
2.CHANCE

QUALITY AND
STANDARDIZED

PHARMACEUTICS ,
MAY BE BASED ON CONCEPTS :
1.VALID MATERIAL (CHEMICAL /
BIOLOGICAL)
2.RATIONAL FORMULATION DESIGN
3.DRUGS TARGET (MOLECULAR
CELLULAR) BASED DELIVERY
SYSTEM DESIGN
4.ACCEPTABLE DOSAGE FORM
DESIGN FOR OPTIMAL
BIOAVAILABILITY OR
BIOEQUIVALENCY

HUMAN

OBAT BAHAN ALAM

PLANTS

STRATEGIC THINKING

MENGANDUNG
TRADITIONAL MENGANDUNG
MISTERI ETNISBANYAK KOMPONEN KOMPONEN UTAMA
JUMLAH BESAR ( > 2
CAM THERAPYDENGAN JUMLAH KECIL

EXTRACT
SIMPLISIA
FORMULATION OR FRACTION
PHYTOPHARMACEUTICALS

3
ISOLATED
SUBSTANCE

ROAD MAP
(THERAPY APPROACH)

SINGLE
COMPOUND

MULTI
COMPONENTS

SINGLE BIOLOGICAL
RESPONSE AND
SOME SIDE EFFECTS

MULTI BIOLOGICAL RESPONSES :

1. COMPREHENSIVE RESPONSE
2. POTENTIATION RESPONS
3. SIDE EFFECTS SUPRESSION
4. TOXIC METABOLITES ELIMINATION
5. SUPPORTING
6. IMMUNOMODULATION
HEIGHT SAFETY CONSIDERATION !!!

+ QUALITY SAFETY +
EFFICACY

Obat Modern
(Single Compound)

and cosmetic

ADEQUACY

HEALTH &
QUALITY
OF LIFE

BIOACTIVITY

Jamu Obat Herbal Fitofarmaka -

- Food
(Multi Components)
- Nutrition

ROAD MAP
( PHARMACEUTIC APPROACH)

SINGLE
COMPOUND

MULTI
COMPONENTS

PENGEMBANGAN
OBAT MODERN

PENGEMBANGAN OBAT
(BADAN POM) :
1. OBAT TRADISIONAL
2. SEDIAAN GALENIK
3. OBAT HERBAL TERSTANDAR
4. FITOFARMAKA
(EKSTRAK / FRAKSI )

BAHAN
OBAT

PELUANG

PROSES

INPUT

OUTPUT

SUMBER DAYA ALAM :

1.TANAMAN OBAT
2.HUTAN TROPIS
3.BIOTA LAUT
4.PRODUK HEWAN
TERNAK

OUTCOMES
IMPACT

PRODUK
OBAT

MASYARAKAT
ISOLATED LEAD COMPOUND

BAHAN
OBAT

INPUT

TANTANGAN

PROSES

TYPE OF THERAPY :
1.
2.
3.
4.
5.
6.
7.

Preventive
Causal
Symtomatic
Supportive
Rehabilitative
Immunomodulative
Cancer Therapy

OUTCOMES
OUTPUT IMPACT
PRODUK
OBAT

IMPROVE :
1.HEALTH STATUS MASYARAKA
2.QUALITY OF LIVE

Obat Modern
OBAT + NUTRISI
NUTRISI + OBAT

Health Food
Food Supplements

(Single Compound)

OBAT + JAMU
JAMU + OBAT

and cosmetic

GREY
AREA

Jamu Obat Herbal Fitofarmaka -

- Food
- Nutrisi (Multi Components)
NUTRISI + JAMU
JAMU + NUTRISI

CAMPUR-CAMPUR TANPA LANDASAN ILMIAH

PERLU REGULASI BERBASIS ILMIAH

RIMPANG KENCUR

CONTOH
PELUANG &
TANTANGAN

1
2

Minyak Kencur

OBAT HERBAL
(EKSTRAK TOTAL)
TERSTANDAR

Etil p-metoksi sinamat

35%

Asam p-metoksi sinamat

Etil-Heksil p-metoksi sinamat
KOSMETIK
TABIR SURYA

FITOFARMAKA

6
OBAT MODERN
Analgesik
Antipiretik

INNOVATIVE RATIONAL CHANCE - COST - PRICE

A
PEGEMBANGA
N
OBAT

Adverseeffect/ToxicityofHM

o Intrinsic orplantassociatedhealthrisk
duetoactiveingredientsinplant.

o Extrinsic ornonplantassociated
whichinclude:

Contamination
(heavymetals,pesticide,microorganism).
Misidentification,substitution,andadulteration.

Safety, efficacy and quality

Lack of research methodology
Inadequate evidence-base for TM/CAM
therapies and products
Lack of international and national standards
for ensuring safety, efficacy and quality
control of TM/CAM therapies and products
Lack of adequate regulation and registration
of herbal medicines
Lack of registration of TM/CAM providers
Inadequate support for research

ACCESS
Lack of data measuring access levels and
affordability
Need to identify safe and effective
therapies and products
Lack of official recognition of role of
TM/CAM providers
Lack of cooperation between TM/CAM
providers and allopathic practitioners
Unsustainable use of medicinal plant
resources

Efficacy
o ScientificevidenceofHM:
Invitrostudies
Invivostudies
Clinicalstudies

o Efficacy
plantconstitue
nt

Efficacy,SafetyandQualityContro

o EfficacyandSafety

Chemicalconstituents.
o Qualitycontroltoassurethecompliance
onqualitystandards.
o Qualitycontrol essentialprerequisite
forensuringsafetyandefficacy.

ProblemswithHMQC

o HM uniqueproblems
inqualitystandardization.
o Morefactorsaffectthequality
o ThefirststepsisGAP
(goodagriculturalpractices).
o ThesecondstepisGMP
(goodmanufacturingprocess)

HMQC

Analyticalmethodstoassureauthenticityandpotency.
Macroscopic,microscopicandorganolepticanalyses,DNA
printing,analysesofmarkeroractivecomponent,
chromatographicfingerprinting.
Markerandactivecomponentiscommonlyusedtomeasu
quality.
EfficacyofHM
multiplecomponent.
Chromatographicfingerprinting

Moreattractive
Macroanalyticalapproach
RequirementproposedbyFDAandEuropeanAgencyforEvaluation

 Sistem Perundangan Kesehatan

Belum banyak informasi Khasiat dan keamanan yang
melalui Uji Klinis
Belum ada kompetensi pada Dokter
Kurangnya perlindungan masyarakat terhadap efek
plasebo iklan obat berbahan alam
Belum terhimpunnya data mengenai obat bahan alam
Indonesia berdasarkan padaevidence based
Kurangnya koordinasi antar institusi dalam penelitian obat
bahan alam Indonesia
Belum ada organisasi profesi kedokteran yang khusus
mendalami herbal Indonesia

WHO
Guidelines

Guidelines for the regulation of herbal

medicines in the South-East Asia Region
These guidelines aim to propose to member states a framework for
facilitating the regulation of herbal medicines/ products used in
traditional medicine
They cover the following issues:
Classification of herbal medicines
Minimum requirements for assessment of safety of herbal
medicine
Minimum requirements for assessment of the efficacy of herbal
medicines
Quality assurance of herbal medicinal products
Pharmacovigilance of herbal medicinal products
Control of advertisements of herbal medicinal products

Quality Control Methods for Medicinal

Plant Materials
This manual describes a series of tests for assessing the
quality of medicinal plant materials. These tests are
designed primarily for use in national drug quality
control laboratories in developing countries and
complement those described in The International
Pharmacopeia.
It pertains to the following;
Powder fineness and sieve size
Macroscopic and microscopic properties
Determination of ash, extractable matter, volatile oils,
bitterness value, hemolytic activity, tannins, pesticide
residues, radioactive contamination etc.

WHO Guidelines on safety monitoring of

herbal medicines in pharmacovigilance
systems
Safety of herbal medicine is an important public health
issue. The guidelines stresses upon:
The importance and process of monitoring the safety of
herbal medicine within the pharmacoivigilance system
Standard definitions of terms related to
pharmacovigilance and safety monitoring of herbal
medicine
Challenges in monitoring the safety of herbal medicine
Need for good communication for ensuring successful
safety monitoring

WHO Guidelines on good agricultural and

collection practices (GACP) for medicinal plants
These guidelines are intended to provide technical
knowledge on obtaining medicinal plant materials of good
quality for the sustainable production of herbal products
classified as medicines.
They apply to the following :

Identification, authentication, cultivation and harvest of

medicinal plants
Good collection practices for medicinal plants
Common technical aspects of good agricultural practices
for medicinal plants in terms of personnel, packaging,
storage and transportation.
Relevant issues of ethical/ legal considerations and
research

General guidelines for methodologies on

research and evaluation of traditional
medicine
These guidelines have been developed to promote the
proper use and development of traditional medicine
and relate to specific issues of methodologies for:
research and evaluation of herbal medicines
research and evaluation of traditional procedure
based therapies
Clinical research norms
Other issues and considerations of ethics, education/
training and surveillance systems.

WHO Global
Strategic
Directions

WHO Traditional Medicine Strategy:

Objectives, Components and Expected Outcomes
Objectives
POLICY:
Integrate
TM/CAM with
national health
care systems,
as appropriate,
by developing
and
implementing
national
TM/CAM
policies* and
programmes

Components

Expected outcomes

Recognition of TM/CAM
Help countries to develop
national policies and
programmes on
TM/CAM

Protection and preservation

of indigenous TM
knowledge relating to health
Help countries to develop
strategies to protect their
indigenous TM knowledge

Increased government
support for TM/CAM,
through comprehensive
national policies on
TM/CAM
Relevant TM/CAM
integrated into national
health care system
services

Increased recording and

preservation of indigenous
knowledge of TM, including
development of digital TM
libraries

WHO Traditional Medicine Strategy:

Objectives, Components and Expected Outcomes
Objectives
SAFETY,
EFFICACY AND
QUALITY:
Promote the
safety, efficacy
and quality of
TM/CAM by
expanding the
knowledge-base
on TM/CAM, and
by providing
guidance on
regulatory and
quality assurance
standards

Components

Expected outcomes

Evidence-base for

TM/CAM Increase
access to and extent of
knowledge of the safety,
efficacy and quality of

TM/CAM, with an
emphasis on priority
health problems such
as malaria and

HIV/AIDS

Increased access to and extent of

knowledge of TM/CAM through
networking and exchange of
accurate information
Technical reviews of research on
use of TM/CAM for prevention,
treatment and management of
common diseases and conditions
Selective support for clinical
research into use of TM/CAM for
priority health problems such as
malaria and HIV/AIDS, and
common diseases

WHO Traditional Medicine Strategy :

Objectives, Components and Expected Outcomes
Objectives

Components

Expected outcomes

RATIONAL USE:
Promote
therapeutically
sound use of
appropriate
TM/CAM by
providers and
consumers

Proper use of TM/CAM

by providers Increase
capacity of TM/CAM
providers to make
proper use of TM/CAM
products and therapies

Basic training in
commonly used TM/CAM
therapies practitioners

Basic training in primary

health care for TM
Practitioners

Proper use of TM/CAM

by consumers
Increase capacity of
consumers to make
informed decisions
about use of TM/CAM
products and
therapies

Reliable information for

consumers on proper use of
TM/CAM therapies
Improved communication
between allopathic practitioners
and their patients concerning
use of TM/CAM

WHO Traditional Medicine Strategy:

Objectives, Components and Expected Outcomes
Objectives
SAFETY,
EFFICACY AND
QUALITY:
Promote the
safety, efficacy
and quality of
TM/CAM by
expanding the
knowledge-base
on TM/CAM,
and by providing
guidance on
regulatory and
quality assurance
standards

Components
Regulation of herbal medicines
Support countries to establish
effective regulatory systems for
registration and quality
assurance of herbal medicines

Expected outcomes
National regulation of herbal
medicines, including
registration, established and
implemented
Safety monitoring of herbal
medicines and other
TM/CAM products and
therapies

Guidelines on safety, efficacy

Technical guidelines and
and quality Develop and
methodology for evaluating
support implementation of
safety, efficacy and quality of
technical guidelines for
TM/CAM
ensuring the safety, efficacy and Criteria for evidence-based
quality control of herbal
data on safety, efficacy and
medicines and other TM/CAM
quality of TM/CAM
products and therapies
therapies

WHO Traditional Medicine Strategy:

Objectives, Components and Expected Outcomes
Objectives

Components

Expected outcomes

ACCESS:
Increase the
availability and
affordability of
TM/CAM, as
appropriate,
with an
emphasis on
access for poor
populations

Recognition of role of
TM/CAM practitioners in
health care Promote
recognition of role of
TM/CAM practitioners in
health care by encouraging
interaction and dialogue
between TM/CAM
practitioners and allopathic
practitioners

Criteria and indicators, where

possible, to measure costeffectiveness and equitable access
to TM/CAM

Increased provision of
appropriate TM/CAM through
national health services

Increased number of national

organizations of TM/CAM
providers

Protection of medicinal
plants Promote
sustainable use and
cultivation of medicinal
plants

Guidelines for good agriculture

practice in relation to medicinal plants
Sustainable use of medicinal plant
resources

INDONESIAN
HERBAL
MEDICINE

TheComponentofHerbalMedicine
o CrudeDrug(simplisia):
partorthewholepartofplant
exudate
dried
Notyetprocessed

o Galenical preparation
Extract
tincture

o Ref:MMI,Pharmacopoeia

IndonesianHerbalMedicine
o

Jamu(TraditionalMedicine)
Safety
Efficacyisbasedonempiricaldata

Standardizedherbalextract
Safety
Efficacyisbasedonpreclinicaldata

Phytopharmaca
Safety
Efficacyisbasedonclinicaldata

Composition

Jamu
Crudedrug
Herbaltea
Extract

Standardized
Extract
Extract

Phytopharmaca
Crudedrug
Extract
Fractionofextract
Maximal5components

LampiranKepMenKesRI
No:761/Menkes/SK/IX/1992

Recommendation:eachproductcontains
1crudedrugorgalenicalpreparation.

Maximum5kindsofcrudedrugsorgalenica
preparations.
Purechemicalentityisforbidden.

PureChemicalEntity(BKO)
Purechemicalentity/syntheticdrug

Jamu
Standardizedextract
Phytopharmaca

Prohibited(Pasal39)
Containspharmacologicallyactivepure
chemicalentitysyntheticorisolated.
Suppositoria,intravaginal,eyedropsand
parentheral preparations.
Containethanol>1.0%

ForeignTraditionalMedicine

Foreigntraditionalmedicinedistributed
inIndonesiamustberegisteredinBPOM
(FoodandDrugAdministrationAgency)

OtherSimilarProduct
FoodSupplement
Theregulationismuchdifferent
Syntheticdrugisallowed
Cocacola
KratingDaeng

SE:1464/DDPR/VII/1983
OTdenganEtanol
Ethanolisallowedandthemaximumis15%
longasneededintheprocess

Ifthecontent>1% :mustbeprintedinthel

PARADIGMA SAAT
INI

PARADIGMA SEHARUSNYA

STRATEGI
PEMERINTA
H

Strategi Pemerintah
Pendekatan : A-B-G
A = Academic
B = Bussiness
G = Government

BPOM
Membagi obat bahan alam
berdasarkan
tingkat pengujiannya :
1. Jamu (empiris)
2. Herbal terstandar (bhn baku
terstandar, uji preklinis)
3. Fitofarmaka (bhn baku terstandar,
uji
klinis)

Dep.Pertanian
Membuat road map tanaman obat di
seluruh Indonesia
BALITRO (Balai Penelitian Tanaman
Rempah dan Obat)
Mendapatkan bibit unggul tanaman
obat

BPPT
Menjadikan pengembangan obat
bahan
alam sebagai salah satu prioritas
program
BPPT sampai tahun 2025

 PB IDI bersama PDUI, PDHMI dan

BALITBANG DepKes RI menyusun
program 150 jam pendidikan herbal
medik dasar bagi para dokter umum

TheIndustryofHerbalMedicine
IOT(TraditionalMedicineIndustry)

IKOT(SmallTraditionalMedicineIndustry

Industrifarmasi(PharmaceuticalIndustry)

Registrationofimportedproductcanbe
conductedbypharmaceuticalcompanyin
distributionsector.

Powder
Weighthomogeneity
Weightof510g,20packsareweighted
< 2packs
< 1pack

10%
8%

Totalplatecount<106
Fungalandyeast,pathogenicmicroorganism,and
aflatoxinlevelasthatofherbaltea.
Additives

Preservativeisnotallowedincrudedrugpowder
Preservativemaybeaddedinextractpowderifneces

Packagingandstorageasstandard

Capsule
Disintegrationtime< 15minutes
Weighthomogeneity

Averageweight120mgorsmaller
< 2deviates10%(solid),7,5%(liquid)
< 1deviate20%(solid),7,5%(liquid)

Watercontentofthecontent
Totalplatecount< 104
Fungalandyeastnumber< 103
Pathogenicmicrobe:negative
Aflatoxin < 30ppm
Additives

Tablet
Weighthomogeneity

< 25mg
2(15%)
26 150mg 2(10%)
151300mg 2(7,5%)
>300mg
2(5%)

1(30%)
1(20%)
1(15%)
1(10%)

Disintegrationtime< 20minutes
Watercontent
Totalplatecount
Yeastnumber
Pathogenicmicrobe
Aflatoxin
Additives

OtherForms

Pill
Taffy(Dodolataujenang)
Lozenges(Pastiles)
InternalLiquid(CairanObatDalam)
Jamuconcentrate(SariJamu)
Parem,PilisdanTapel
Plaster(Koyok)
TopicalLiquid
Ointment/Cream

KepmenNo659/Menkes/SK/X/1991
TentangCPOTB

IOTandIKOThavetoimplementCPOTB(GM
fortraditionalmedicine)
Industrywithasset<50millionhasto
improveitscapacityandby1997already
implementCPOTB.

CertificateofCPOTBisissuedbyregional
office(KantorWilayah)basedonreportby
HeadofInspectorateOffice.

GoodManufacturingPractices
Peraturan BPOMNoHK.00.05.4.1380
Pedoman CPOTB

Didnotrefertothepreviouslegaldocumen
onCPOTB.
Thereisnoclauseonthenecessityof
pharmacist.

Coveragealmostthesamewiththepreviou
guideline.

Coverage

personnel,
building,
equipment,
sanitationandhygiene,
storageofrawmaterials,
processingandpackaging,qualitycontrol
selfinspection,
documentation,
handlingofproductsalreadyinthemarket

Terminology
o
o
o
o
o
o
o
o

HerbalMedicine
Phytomedicine
Phytopharmaca
Jamu
Kampo
TraditionalMedicine
NaturalMedicine
NativeMedicine

Implementasinya
Herbal yang dapat digunakan dalam
sistim
pelayanan konvensional adalah :
- fitofarmaka
- herbal terstandar (pelayanan
penelitian)
- jamu (usul : Badan Litbangkes)

 Imunomodulator, yaitu: herbal yang dapat

meningkatkan kekebalan tubuh, antara lain
Meniran, Lidah buaya, Sambiloto, Temulawak
Anti Inflamasi, antara lain : Temulawak,
Lempuyang, Jahe, Lengkuas
Anti Parasit: Terhadap Brugia malayi,
B.Timori, Wuchereria bancrofti, maka herbal
ini dapat mengobati penyakit di atas yaitu:
Leuchena leucocephala, Tinospora
(brotowali), Temuireng.
Antivirus : Meniran, Pasak Bumi, Beluntas,
dan Jambu Biji

 Antibiotik: Berkhasiat terhadap jamur Candida

albicans, Tricophyton mentagophytes,
Staphylococcus aureus,
Pseudomonas aeruginosa dan Microspora canis.
Beberapa Herbal yang berkhasiat antara lain :
Meniran,
Beluntas, Lengkuas dan Tabat Barito.
Anti Hipercholesteremia: Labu Siam, Temulawak,
Daun Salam, Kunyit, Sambiloto, dan Mengkudu
Anti Hipertensi : Belimbing Wuluh, Daun Seledri,
Bawang Putih, Buah Leunca, Kayu Manis.
Anti Oksidan : Temulawak, Cabai, Buah
Mengkudu, Lengkuas, Daun Salam, Teh, Lada
Hitam

 Anti Kanker: Sirih Merah, Temu putih,

Rumput Mutiara, Keladi Tikus, Jinten
Hitam, Buah Mengkudu, Bawang Putih
Kosmetika: Bengkoang, kencur, kulit
manggis, melati, daun jambu mede.
Nutrisi dan Minuman: Temulawak,
Kunyit Asam, Pegagan, Sari Pace,
Madu, Beras Kencur, permen herbal

Broad Use and Appeal

In many developing
and developed
countries as often
stated in government
reports the majority
of the population
continues to use TM
to meet its primary
health care needs.

Percentage of Population used CAM

Atleast Once

Sources: Fisher P & Ward A, 1999; Health Canada, 2001, World Health Organization, 1998.7,8,6

Commonly used TM/CAM therapies

and therapeutic techniques

More and More Countries are

Regulating Herbal Medicines

Source: World Health Organization, 199841 and data collected by World Health Organization during period 19992001.

Thank You