Dr.T.V.Rao MD
3/23/16
DRUG RESISTANCE A
Anti-TB
CONCERN TO THE
HUMAN
medicines
have
RACE IN TUBERCULOSIS
been used for
decades, and
resistance to
them is
widespread. TB
strains may be
resistant to one
or more
RIFAMPICIN-RESISTANT
TUBERCULOSIS
(RR-TB) IS
Rifampicin-resistant
tuberculosis (RR-TB) is
caused by TB bacteria
that do not respond to
rifampicin, one of the
most effective anti-TB
medicines, requiring
longer treatment and
more medication than
patients with
rifampicin-susceptible
disease
MULTIDRUG-RESISTANT
TUBERCULOSIS (MDR-TB) IS
Multidrug-resistant
resistant TB (XDR-TB), is
a form of multidrugresistant tuberculosis
that responds to even
fewer available
medicines, including the
two most effective
classes of second-line
anti-TB medicines.
XDR-TB
drug-resistant
Extensively
TB (XDR-TB) has
been reported
by 105 countries
in 2014. On
average, an
estimated 9.7%
of people with
MDR-TB have
DETECTION OF MDR-TB
PATIENTS
DRUG SUSCEPTIBILITY
TESTING
More TB patients were reported to have
MDR-TB TREATMENT
A total of 110 000
TREATMENT OUTCOMES
Only 50% of the MDR-TB
TRENDS
An analysis of trends
PRIORITY ONE
PREVENT MDR-TB AS A FIRST PRIORITY
PREVENT THE
DEVELOPMENT OF
DRUG RESISTANCE
THROUGH HIGH
QUALITY
TREATMENT OF
DRUGSUSCEPTIBLE TB
PRIORITY TWO
SCALE UP RAPID TESTING AND DETECTION
OF ALL MDR/RR-TB CASES
EXPAND RAPID
TESTING AND
DETECTION OF
DRUGRESISTANT TB
CASES
PRIORITY THREE
PROVIDE IMMEDIATE ACCESS TO
EFFECTIVE TREATMENT AND PROPER CARE
Ensure prompt
access to
appropriate MDRTB care, including
adequate supplies
of quality drugs
and scaled-up
country capacity
PRIORITY FOUR
PREVENT TRANSMISSION THROUGH
INFECTION CONTROL
Implement appropriate
TB infection control
measures and quickly
enrol diagnosed
patients on effective
treatment to minimize
the risk of disease
transmission
PRIORITY FIVE
INCREASE POLITICAL COMMITMENT
WITH FINANCING
Underpin and sustain the
REFERENCES
WHO FACTS AND CONCERNS ON MDR TB
CDC TRENDS ON MDR- TUBERCULOIS
ATTENTION OF VIEWERS
I am thankful to many in the world who made me to achieve my desired goals faster than I
thought, having > 3-5 million health professionals share and utilize my knowledge for the
benefit of mankind, Today I wish to be freelancer to the world to create interest in Medical,
Clinical and Diagnostic Microbiology with more emphasis on Infectious diseases and Hospital
associated Infection wish to be your partner in educating many millions who know well the
importance of Infectious diseases
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