Childhood
Clinic: less acute lesions
Lesions less exudative, drier,
>papular
Locations: antecubital, popliteal
fossae, flexor wrist, eyelids, face,
around the neck
lichenified, slightly scaly/ infiltrated
plaques
Minor
features
Intense pruritus
Morphological characteristic of AD
Investigation
SPT/RAST
SPT/RAST
Anti inflammatory
Treatment
TOPICAL EMOLLIENT
BASIS TOPICAL TREATMENT :
2 3 X / DAY
WATER LOSS
ITCHING
Topical treatment
ANTIBIOTIC
FUSIDIC ACID
GRAM (+)
TETRA CYCLINE
SKIN CLEANSER 10% POVIDONE
IODINE
GENERALIZED INFECTION : ANTI
OTHER TREATMENT
STRATEGIES
UVA PHOTOTERAPY
CICLOSPORIN
IF
1st generation
2nd generation
Alkylamine
Chlorpheniramine
Acrivastine
Piperazine
Hydroxyzine
Cetirizine,
levocetetirizine
Piperidine
Cyproheptadine
Astemizol
Desloratadine
Fexofenadine
Loratadine
Ethanolamines
Diphenhidramine
Ethylenediamines
Pyrilamine
Phenothiazine
Promethazine
Proinflammatory cytokines
Adhesion protein
Antiallergic activities
Anti-inflammation effect