Lecture 15: Pathogenicity

Dr. Dimos

Pathogenicity Vs. Virulence

Pathogenicity: is a broad concept
that describes an organisms potential
to cause infection or disease.
Virulence: is the accurate term for
describing the degree of pathogenicity.
The virulence of a microbe is
determined by its ability to (1)
establish itself in the host and (2)
cause damage.

The steps involved when a microbe

causes disease in a host.

echanisms of adhesion
by pathogens.

Three ways microbes

damage the host.

The origins and effects of circulating

exotoxins and endotoxin.

Stages in the course of infection

and disease

Dashed lines represent periods with a

variable length.

Disease Table Continued:

Gastrointestinal
Tract

Salmonella

Slamonella Adhering and Invading

Gut Mucosa

Pathogenicity
Island

Structure of the Salmonella type III

secretion system (T3SS)

Pathogenicity Island

Immune System

Antibody
Molecule

The Five Types of Antibodies

How Antibodies Interact

with Antigens

The Process of
Anaphylaxis and
Allergy