KEMOTERAPI

CA RECTUM

TINJAUAN PUSTAKA
CA REKTUM

Definisi
Ca
Rekti
adalah
kanker yang terjadi
pada rektum. Rektum
terletak di anterior
sakrum and coccyx
panjangnya kira kira
15 cm.

940

Gejala Klinis
Perubahan pola
dan bentuk
defekasi
BB menurun tanpa
sebab jelas
Mual muntah
Letuh, lesu

Diagnosis

CEA (Carcinoma Embrionik Antigen)

Digital rectal examination (DRE)

Barium Enema
Sigmoidoscopy

Colonoscopy

Biopsy

STADIUM
THE AMERICAN JOINT COMMITTEE ON CANCER (AJCC)
TNM STAGING SYSTEM

Stadium o

TNM
Stadium

Modified
Deskripsi
Dukes Stadium

T1 N0 M0

Tumor terbatas pada submucosa

T2 N0 M0

B1

Tumor terbatas pada muscularis propria

T3 N0 M0

B2

Penyebaran transmural

T2 N1 M0

C1

T2, pembesaran kelenjar mesenteric

T3 N1 M0

C2

T3, pembesaran kelenjar mesenteric

T4

C2

Penyebaran ke organ yang berdekatan

Any T, M1 D

Metastasis jauh

Tatalaksana :
Pembedahan
Radiasi

Kemoterapi

Prognosis

5-year survival
rates :

Stadium

I - 72%
Stadium II - 54%
Stadium III - 39%
Stadium IV - 7%

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