Lecture (5)
By
Dr.Dalia M. Mohsen
Objective
Comparison between viruses and
bacteria
Atypical virus like agents.
Virus and cancer
Discuss antiviral therapy
Size
20-300 nm
1000 nm
Genome
(type of nucleic acid)
DNA or RNA
but
not both
Cell wall
Envelope
present
in some
viruses
Cell wall
Ribosomes
No ribosomes
Ribosomes
Sensitivity to
antibiotics
Growth in culture
media
Grow only in
living host cell
Viruses implicated in
human
cancer Tumor
Virus
DNA Viruses:
Human papiloma
viruses(HPV)
Carcinoma of skin
Nasopharyngeal
Epstein Barr virus (EBV) carcinoma
Hepatitis B virus (HBV)
RNA viruses:
Human T-cell
Lymphotropic
Retrovirus (HTLV-1 )
Hepatocellular
carcinoma
Adult T-cell leukemia
lymphoma
Liver cancer
Antiviral therapy
Since
viruses
are
obligate
intracellular
selectively
affecting
the
inhibits
cell
the
(selective
virus
without
toxicity).Few
virus
attachment,
penetration,
with
virus
adsorption
or
and
replication.
with virus
maturation
Thank
you