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Micropenis : stretched penile length of less

than 2.5 standard deviations (SDs) below the
mean for age.
The penis grows very little until puberty
when testosterone levels begin to rise.


Fetal production of testosterone and its

peripheral conversion to dihydrotestosterone
(DHT) is necessary for normal male
After birth, gonadotropin (luteinizing
hormone [LH] and follicle stimulating
hormone [FSH]) and testosterone production

Beginning at about age 1 week, gonadotropin

and testosterone levels begin to rise again to
pubertal levels, peaking at age 1-3 months
Decreasing to prepubertal levels by age 6

Genetic syndromes in which micropenis may

be a feature include Prader-Willi, Klinefelter,
and Noonan syndromes


Testosterone therapy in the form of 3-6

monthly intramuscular (IM) injections
Testosterone therapy has generally been
found effective in treating micropenis due to
testosterone deficiency.