PHARMACOTHERAPY

Learning outcome :

Be able to choose drugs for the patients rationally

( based on efficacy, safety, acceptability, cost

effectiveness )
Learning objective :

Be able to select drug dosage forms according to

patient

Be able to decide drug dose regimens to the patient

To consider about drug interaction and adverse drug

reactions

Demonstrate the ability to do the rational drug

prescribing

DOSAGE FORM OF DRUG

THE CHOOSE REASON :
- DESEASE FACTOR : Accut / Chronis,
Site of desease
- PATIENT FACTOR : Baby, children,adult,
vomitus, sosial economic
- DRUG FACTOR : bitter substantif
capsule
Iritation substantif not peroral

SOLID DOSAGE FORM

1. PULVIS (bulk powder)
Ex : Herocyn, Purol, Caladin
PULVERES (devide powder) for children
Ex : Puyer
2. TABLET
Dragee
becefort
effervescen supradyn tab eff., redoxon
vaginal
Mebinol complex
lozenges
Sentril lozenges
chewable
Rovigon
3. CAPSULE
hard
tetracycline cap
soft
pharmaton formula, hemaviton
4. SUPPOSITORIA ( anal, vaginal )
Anal
dulcolax supp, anusol supp
Vaginal flagystatin supp

SEMI SOLID DOSAGE FORM

1. UNGUENTUM / OINTMENT
Terracortril topical oint,Terramycin opth.oint.
2. CREMORES / CREAM
Esperson cream
3. PASTA
Sensodyn pasta
4. GEL / JELLY
Bioplacenton gel
5. SAPO / SOAP ---- J F Sulfur sapo, Sapo kalinus

LIQUID DOSAGE FORM

1.
2.
3.
4.
5,
6.
7.

SOLUTIONES : sol. rivanol, betadine sol.

SYRUP : benadryl syr
ELIXIR : panadol elixir
GUTTAE / DROPS visine, tempra drop
INJECTION xylomidone inj, adrenaline inj
ENEMA laxadine enema
COLLUTORIA listerine
GARGARISM betadine gargle
8. DOUCHE Betadine vaginal douche, lady care
9. SUSPENSION bactrim susp, combantrin susp
10. EMULSION scott emulsion

- Steril drug
Parenteral : steril,isotonis,isohidris, apyrogen
- Injection,infus
- AEROSOL / INHALASI
Allupent inhaler
Ventolin inhaler
Vicks inhaler

DRUGS DOSE
MINIMAL DOSE: minimal amount of drug which still give
therapeutic effect
THERAPEUTIC DOSE / USUAL DOSE : amount of drug
which can give therapeutic effect
MAXIMAL DOSE : a maximal amount of drug which still
safe be given without acute toxicity symptom
TOXIC DOSE : amount of drug which give toxicity
symptom
LETHAL DOSE : amount of drug that can kill some of
animal laboratory. LD50 mean 50 % animal lab.was killed
FATAL DOSE : amount of drug that can kill a person

THE PRESCRIPTION

Request from doctor to pharmacist prepare the drug which

finally passed to patient.
An order written by a physician, dentist, veterinarian,
directing to pharmacist to compound and dispense
medication for a patient

The part of prescription

1. Inscriptio dr. identify, town, date, R/
2. Ordinatio/Praescriptio name, form,
quantity
3. Signatura how to use, patient identify
4. Subscriptio dr. sign

EXAMPLE OF PRESCRIPTION
Dr.Iwan
Lissence/Izin
Address
R/ Amoxicillin 250 mg caps No.XV
S.3 d.d.caps I
==== sign
Pro : Amin ( dewasa )
Add: jl. Gorris 1 Dps

Dps Mrt 2010

R/ = Recipe = siapkanlah
S.u.e.=Signa usus externus=tandailah untuk pemakaian luar
S.3 d.d.= Signa ter de die=tandailah 3 x sehari
d.t.d.=da tales dosis= masing-masing dosisnya seperti diatas
fl. = flash= botol kecil

Pulvis : R/ Herocyn powder fl. no. I

S.u.e.
=====sign
Pulveres : R/ Amoxicillin mg 125
Paracetamol mg 200
M. f. pulv. dtd. no. XV
S. 3 d.d.pulv. I
====== sign

Tablet : R/ Antalgin 500 mg tab. No. XV

S. 3 d.d. tab. I
======
Capsul : R/ Tetracyclin 250 mg Caps. No.XX
S. 4 d.d.Caps I
======
Suppositoria: R/ Anusol Suppos. No.V
S.1d.d.I intra anus
=====
Syrup : R/ Panadol Syr. fl. No. I
S. 3 d.d. Cth. I
=====
Drop / Guttae : R/ Colme eye drop fl.No. I
S. 4 d.d.gtt. I
=====
Solution : R/ Betadine sol.fl. No. I
S.u. e.
=======

Ointment : R/ Terracortryl oint tube no. I

S. u. e.
=====
Cream : R / Counterpain cream tube no I
S.u.e.
=====
Parenteral : R/ Adrenalin inj. ampul no. X
S i.m.m.
=====
R/ Xylomidon vial no. II
S. i. m.m.
======
R/ Dextrose infus fl.no. I
S.i.m.m.
=====

THANK YOU