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DEMOSTRACION DE INMUNIDAD FRENTE A TUMORES

ANTIGENOS TUMORALES

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

INMUNIDAD ANTITUMORAL

CANCER IMMUNOSURVEILLANCE

IL10

LINFOCITOS CD8+ Y CD4+

CANCER IMMUNOSURVEILLANCE

IKDC: DC PRODUCTORA DE IFN

NKT: DC RECONOCIMIENTO GLICOLIPIDOS

CANCER IMMUNOSURVEILLANCE

NK(NKGD2)

CANCER IMMUNOSURVEILLANCE

LT

CANCER IMMUNOSURVEILLANCE

ANTICUERPOS

CANCER IMMUNOSURVEILLANCE

NK, NKT, LT

HYPOTHETICAL LINK ENDOGENOUS SUPPRESION AND IMMUNOSURVEILLANCE

CANCER IMMUNOSURVEILLANCE

MECHANISMS OF TUMOR ESCAPE FROM THE IMMUNE SYSTEM

MIELOID SUPRESSOR CELLS

INDOLEAMINE 2,3
DIOXYGENASE

MECHANISMS OF TUMOR ESCAPE FROM THE IMMUNE SYSTEM

CARACTERISTICAS
CELULA
TUMORAL

VIAS DE SEALIZACION CELULAR: FACTORES CRECIMIENTO vs. FACTORES ANTICRECIMIENTO

MICROAMBIENTE TUMORAL

LAS 3 Es DE INMUNOEDICION

LAS 3 Es DE INMUNOEDICION

CITOQUINAS

CELULAS TUMORALES
VARIANTES CELULAS TUMORALES

FASE ELIMINACION

QUIMIOQUINAS
Bloquea
ANGIOGENESIS

LAS 3 Es DE INMUNOEDICION

LAS 3 Es DE INMUNOEDICION

LAS 3 Es DE INMUNOEDICION

DENDRITIC-CELL DEFECTS
NORMAL DC DIFFERENTIATION

FUNCTIONAL CONSEQUENCES OF ABNORMAL DIFFERENTIATION IN CANCER

FUNCTIONAL CONSEQUENCES OF ABNORMAL DIFFERENTIATION IN CANCER


STAT3-MEDIATED SIGNALLING IN ABNORMAL DIFFERENTIATION OF DCs

FUNCTIONAL CONSEQUENCES OF ABNORMAL DIFFERENTIATION IN CANCER


NFkB-MEDIATED SIGNALLING IN ABNORMAL DIFFERENTIATION OF DCs

STAT3 IN THE TUMOR MICROENVIRONMENT

STAT3 CONSTITUTIVE ACTIVATION

STAT3 IN THE TUMOR MICROENVIRONMENT

STAT3 IN THE TUMOR MICROENVIRONMENT

HEMATOPOIETIC PROGENITOR CELLS

STAT3 IN THE TUMOR MICROENVIRONMENT

STAT3 IN THE TUMOR MICROENVIRONMENT

TARGETING STAT3 FOR CANCER IMMUNOTHERAPY

INHIBITORY B7-FAMILY MOLECULES IN THE TUMOUR MICROENVIRONMENT

INHIBITORY B7-FAMILY MOLECULES IN THE TUMOUR MICROENVIRONMENT

INHIBITORY B7-FAMILY MOLECULES IN THE TUMOUR MICROENVIRONMENT

INHIBITORY B7-FAMILY MOLECULES IN THE TUMOUR MICROENVIRONMENT

INHIBITORY B7-FAMILY MOLECULES IN THE TUMOUR MICROENVIRONMENT

SUPPRESSIVE MECHANISM OF TUMOUR ENVIRONMENTAL REGULATORY T CELL

NFkB SIGNALLING PATHWAYS LINKING INFLAMMATION AND IMMUNITY TO CANCER DEVELOPMENT AND PROGRESSION

NFkB SIGNALLING PATHWAYS

NFkB SIGNALLING PATHWAYS LINKING INFLAMMATION AND IMMUNITY TO CANCER DEVELOPMENT AND PROGRESSION

NFkB TUMOUR PROMOTING FUNCTIONS

NFkB SIGNALLING PATHWAYS LINKING INFLAMMATION AND IMMUNITY TO CANCER DEVELOPMENT AND PROGRESSION

CANCER CELL NECROSIS IS AN IMPORTANT DRIVER OF TUMOUR PROGRESSION

not enough of a good thing PARADIGM

NATURAL AND ADAPTIVE Tregs

too much of a bad thing PARADIGM