Activity of Leaf
Essential Oil
of Citrus sinensis (L.)
Osbeck on AlloxanInduced Diabetic Rats
AIM
To investigate the antihyperglycemic
activity of leaf essential oil of Citrus
sinensis (Rutaceae) in alloxan induced
diabetic rats.
Available Treatments
Insulin
Sulfonlyureas
Biguanides
Glinides
Many of these treatment agents have a
number of serious adverse effects such as
hypoglycemia, drug-resistance, dropsy, and
weight gain
Antihyperglycemic Activity
Most medicinal plants
ability to restore the function of pancreatic
tissues by causing an increase in insulin
output
inhibit the intestinal absorption of glucose
or facilitating metabolites in insulin
dependent processes
D-Limonene
an oil nutrient called a terpene
natural compound found in lemon and orange
peels
It has potent antioxidant and antiinflammatory properties
offers assistance for a variety of metabolic and
health problems, has anti-cancer properties,
and even helps with weight management.
CONLUSION
It is concluded that leaf essential oil of
Citrus sinensis possesses significant
antihyperglycemic effect on alloxan
induced diabetic rats at the dose tested.