ANATOMY AND PHYSIOLOGY OF

INTEGUMENTARY SYSTEM
 RISK FACTORS

A number of factors can increase your risk of developing certain types of

dermatitis. Examples include:
Age
Allergies and asthma
Occupation
Health conditions


PREDISPOSING/ NON-MODIFIABLE FACTORS
PRECIPITATING/ MODIFIABLE FACTORS

Predisposing/ Non-modifiable Factors

Genetics
Abnormal function of the immune system

PRECIPITATING/ MODIFIABLE FACTORS

ENVIRONMENT
ACTIVITIES THAT MAY CAUSE SKIN TO BE MORE SENSITIVE
DEFECTS IN THE SKIN BARRIER THAT ALLOW MOISTURE OUT AND
GERMS IN SOAPS AND CLEANSERS
EXAMPLES OF OTHER THINGS THAT CAN IRRITATE THE SKIN INCLUDE:
PERFUME
MAKEUP
DUST AND SAND
CHLORINE
SOLVENTS
IRRITANTS IN THE ENVIRONMENT
CIGARETTE SMOKE
PATHOPHYSIOLOGY
Patient X

genetic predispositions, Possible cause:

environmental triggers, USANA intake, application of agua
and immune dysregulation oxinada

widening of intercellular
spaces between
keratinocytes

elongation of intercellular
bridges

disruption of desmosomes

Formation of microvesicles

Accumulation of fluid leads

to formation of intra
epidermal vesicles
 Parakeratosis Acanthosis

Droplets of plasma
accumulated in the
mounds of parakeratosis

Superficial dermal
lymphohistiocytic
inflammatory infiltrate

Swelling of endothelial cells

S/S ,(+) lesion in both

hand, swelling, (+) for
rashes,(+) leathery
patches and dark color of
patches

DYSHIDROTIC
ECZEMA
 COMPLICATIONS

Asthma and hay fever Others
Chronic itchy, scaly skin Psychological effects
Skin infections Bullying
Eye problems Problems sleeping
Irritant hand dermatitis Self-confidence
Allergic contact dermatitis
Sleep problems
Behavioural problems