Ainur Abdrakhmanova
Diagnostic tests
CBC (leukopenia, thrombocytopenia in
50%)
Chemistry panel: liver and kidney function
tests
ESR: inflammation marker, used to monitor
Urinalysis: presence of protein,
wbc, rbc, cellular casts
BUN/creatinine: high
Complement: low
CRP: inflammation marker
Anti phospholipid Ab: in 60%
Anti - Ro(SSA) and Anti La(SSB): against RNA
proteins, in 35-40% and 15% respectively
Anti-Sm Ab: in 25-30%, specificity is 99%
Anti-dsDNA: in 25-85%, specificity is almost
100%, titers correlate with disease activity