Journal Reading

PULMONOLOGY SUBDIVISION

Evaluation of predictive value of pleural

CEA in patients with pleural effusions and
histological ndings:
A prospective study and literature review

Feni Fardila

Internal Medicine Department

Medical Faculty Of Andalas University
Dr. M. Djamil Hospital Padang
2017
Pleural Effusion (PE)

Jaundice, liver
failure,prolonged
history of alcoholism

Severity of alcoholic
Maddreys
discriminant function

Malignant
Mortality of 20 to 30%
within 1 month afterpleural
presentation and 30effusion (MPE)
to 40% within 6 2030% of
months after cases
presentation
Pleural Effusion (PE)
But
Thoracentesis
Pleural
To
A recent
differentiate
3050%meta-analysis,
of patients
betweenwith
evaluating
benign
MPEPEexhibit
the
(BPE)
clinical
negative
and utility
pleural
of some
cytology
pleural
(PC)
TM
Pleural Effusion (PE)
The aim of this study
MATERIAL AND METHODS
Study
design and Patients
oversight
Clinical
Multicenter,
diagnosis of
randomised,
alcoholic
double blind
hepatitis

From January
2011 -February
Data collected
2014 at 65
by site
hospitals
investigative
across the
teams
United
Kingdom
STATISTICAL ANALYSIS
Results

3 year5234 patients
1103 patients were four treatment groups
randomly assigned

276 to the placebo

placebo group, 277 to
the prednisolone All the patients were
placebo group, 276 to followed for 12 months
the pentoxifylline or until the time of their
placebo group, and 274 death
to the prednisolone
pentoxifylline group
DISCUSSION

Significant advantage with 28 day mortality

with prednisolone

Lower 28 day mortality,infection and

kidney injury in STOPAH than other trial

The use of liver biopsy, not only

based on clinical diagnosis

Administration of 40 md prednisolone
daily for a month benecial effect on
short term
DISCUSSION
The p-CEA/s-CEA ratio was higher in patients with NSCLC and MPE (exc
 CONCLUSION

s-CEA
p-CEA
The combination
is
measurement
not useful
ofin
p-CEA
is
patients
more
and
accurate
with
PC should
PE due
( betoused
its low
in all
accuracy
patients with PE
THANK YOU