IRREVERSIBLE INJURY

PPDS I ANESTESI DAN TERAPI INTENSIF

 Apakah Irreversible Injury ?

Cell injury results when cells are stressed so severely that they are no longer able to
adapt or when cells are exposed to inherently damaging agents or suffer from intrinsic
Irreversible Injury
NECROSIS
 NECROSIS

Necrotic cells are unable to maintain membrane integrity, and their contents often leak
 APOPTOSIS

Apoptosis, a programmed cell death, can be physiological or pathological and often

results in the elimination of abnormal or unwanted cells (it is as if these cells commit
suicide by eliminating themselves through the activation of the apoptotic machinery).
APOPTOSIS vs NECROSIS
 Kesimpulan

The cellular response to injurious stimuli depends on the type of injury, its duration, and
Terima Kasih