SEPSIS DAN

SIRS

Dokter pembimbing
dr.Pribadi Arief Sp.B-KBO

RETNO MANGGALIH
030.11.244
Bone RC, Balk RA, Cerra FB, et al. American College of Chest Physicians/Society of Critical Care Medicine Consensus
Conference:
definitions for sepsis and organ failure and guidelines for the use of innovative therapies insepsis.Crit Care Med.
1992;20(6):864-874.
 SEVERE
SIRS SEPSIS
SEPSIS

A clinical response arising SIRS with a presumed Sepsis with 1 sign of organ
from a nonspecific insult, or failure
including 2 of the Confirmed infectious Cardiovascular (refractory
following: process hypotension)
Temperature 38oC or 36oC Renal
HR 90 beats/min Respiratory
Respirations 20/min Hepatic
WBC count 12,000/mm3 or Hematologic
4,000/mm3 CNS
Unexplained metabolic
acidosis

Bone RC, Balk RA, Cerra FB, et al. American College of Chest Physicians/Society of Critical Care Medicine Consensus
Conference:
definitions for sepsis and organ failure and guidelines for the use of innovative therapies insepsis.Crit Care Med.
1992;20(6):864-874.
 SEVERE
SIRS SEPSIS
SEPSIS

Multiple organ
dysfunction syndrome SEPSIS SYOK
(MODS)

qSOFA (Quick SOFA)

Criteria
Respiratory rate 22/min
Altered mentation
Systolic blood pressure
100 mm Hg
 Early goal directed therapy

Tujuan fisiologis selama

6 jam pertama

1) Tekanan vena sentral (CVP) 8-12mmHg

2) Tekanan arterial rata-rata (MAP) 65mmHg
3) Saturasi oksigen vena sentral (SavO2) 70%
4) Urine output 0,5ml/kg/jam