ADITYA PRAMAVIRI
Definition
postrenal
ADITYA PRAMAVIRI
Hormone Regulation
Testosterone secretion is regulated by the
hypothalamic-pituitary-gonadal axis
2. Circulating testosterone
Hypothalamic LH secretion
If prostate cells are deprived of androgenic
stimulation
apoptosis (programmed cell death)
Pharmacological side-effects :
Gynaecomastia
Breast pain
Hot flashes
Bicalutamide more favourable safety and tolerability profile than
nilutamide and flutamide
All three agents share a common liver toxicity and liver enzymes must
monitored regularly
TERIMA KASIH