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  • K4 - Cell Junction-Intercellular Communication

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    Jane Andrea Christiano Djianzonie
    16 tayangan26 halaman
    This document provides an overview of cell junctions and their components. It discusses the main types of cell junctions: 1) occluding junctions like tight junctions that control permeability between cells, 2) anchoring junctions like adherens junctions and desmosomes that attach cells together, and 3) communicating junctions like gap junctions that allow small molecules to pass between cells. It describes the key membrane proteins, cytoskeletal elements, and extracellular matrix involved in forming cell junctions and maintaining cell-cell contacts which are essential for many cellular functions and processes.

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    Cell Junction-Intercellular Communication

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    This document provides an overview of cell junctions and their components. It discusses the main types of cell junctions: 1) occluding junctions like tight junctions that control permeability between cells, 2) anchoring junctions like adherens junctions and desmosomes that attach cells together, and 3) communicating junctions like gap junctions that allow small molecules to pass between cells. It describes the key membrane proteins, cytoskeletal elements, and extracellular matrix involved in forming cell junctions and maintaining cell-cell contacts which are essential for many cellular functions and processes.

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    © All Rights Reserved
    Unduh sebagai PPTX, PDF, TXT atau baca online dari Scribd
    Tandai sebagai konten tidak pantas
    16 tayangan26 halaman

    K4 - Cell Junction-Intercellular Communication

    Diunggah oleh

    Jane Andrea Christiano Djianzonie
    This document provides an overview of cell junctions and their components. It discusses the main types of cell junctions: 1) occluding junctions like tight junctions that control permeability between cells, 2) anchoring junctions like adherens junctions and desmosomes that attach cells together, and 3) communicating junctions like gap junctions that allow small molecules to pass between cells. It describes the key membrane proteins, cytoskeletal elements, and extracellular matrix involved in forming cell junctions and maintaining cell-cell contacts which are essential for many cellular functions and processes.

    Hak Cipta:

    © All Rights Reserved
    Unduh sebagai PPTX, PDF, TXT atau baca online dari Scribd
    Tandai sebagai konten tidak pantas
    dari 26

    Basic

    Science Cell Junction


    Interactions Between Cells
    Their Environme

    Departemen
    Introduction
    Cell contacts essential for
    Introduction contd
    Cell Junctions components

    Membrane
    proteins
    Cytoskeletons
    Extracellular Matrix
    Extracellular matrix: a complex of nonliving
    macromolecules manufactured by the cells & exported
    into extracellular space. Macromolecules fibronectin,
    laminin, etc.
    Cell Junctions
    Classification:
    Types Based on Function:
    Cell Junctions Map:
    1. Occluding Junctions
    Tight Junctions
    Also called zonula occludens
    Permeability of tight junctions
    2. Anchoring Junctions
    Widely distributed
    2. Anchoring Junctions
    contd
    A. Adherens Junctions:
    Zonula Adherens
    2. Anchoring Junctions
    contd

    The folding of an epithelial sheet to form an epithelial tube


    The oriented contraction of the bundles of actin filaments running along adhesion belts
    causes the epithelial cells to narrow at their apex and helps the epithelial sheet to roll
    up into a tube. An example is the formation of the neural tube in early vertebrate
    development. Although not shown here, rearrangements of the cells within the
    epithelial sheet are also thought to have an important role in the process
    2. Anchoring Junctions
    contd
    B.Desmosomes/macula adherens:
    B.Desmosomes/macula adherens contd:
    Autoimmune disease
    disrupt desmosomes
    blistering of skin
    2. Anchoring
    Junctions contd
    C.Hemidesmosomes:
    2. Anchoring Junctions
    contd
    D.Focal adhesions:
    3. Communicating
    JunctionsGap
    Gap Junctions/nexus: Junctions
    Gap Junctions Contd
    Gap Junctions/nexus:
    Cell JunctionsSummary
    Cell JunctionsSummary
    contd
    References
    1. Molecular Biology of the Cell, 4th edition, Bruce
    Alberts, Alexander Johnson, Julian Lewis, Martin
    Raff, Keith Roberts, and Peter Walter, New York:
    Garland Science; 2002.
    2. Basic Histology Text & Atlas , 10th ed. , L. Carlos
    Junquira MD, Jose Carneiro MD, Robert O. Kelley
    PhD, Lange Medical Books, Mc Graw-Hill
    3. Histology and Cell Biology: an Introduction to
    Pathology, Epithelium, 2nd edition, Abraham L.
    Kierszenbaum M. D. Ph. D, Mosby Elsevier Inc.
    2007, Philadelphia.
    4. Functional Ultrastructure Atlas of Tissue Biology
    and Pathology. Margit Pavelka, Jrgen Roth. 2005.
    Springer-Verlag/Wien. NewYork.

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