Terapi

insulin
 Indikasi
Penurunan BB yang cepat
Hiperglikemia dgn asidosis laktat
Gangguan fungsi ginjal dan hati yg berat
Hiperglikemia berat disertai ketosis
Ggal dgn pemberian OHO dosis optimal
Kontraindikasi dan atau alergi terhadap OHO
KAD
HONK
Kahamilan dg DM
Stres berat (inf.sistemik, op besar, IMA dan stroke)
Insulin Onset of Peak action Effective
preparat action (menit) duration of
(menit) action
(hours)
Insulin prandial
Human insulin
short acting
Insulin 30-60 30-90 3-5
reguler(actrapid
,humulin R)
Insulin analog
rapid acting
Insulin lispro 5-15 30-90 3-5
(humalog R)
Insulin glulisine 5-15 30-90 3-5
(apidra)
Insulin aspart 5-15 30-90 3-5
(novo rapid )
Insulin Onset of Peak action Effective
preparat action (hours) duration of
(hours) action
(hours)
insulin
intermediate
acting
NPH (insulatard, 2-4 4-10 10-16
humulin N)
Insulin long
acting
Insulin glargine 2-4 No peak 18-26
(lantus)
Insulin detemir 2-4 No peak 22-24
(levemir)