Course Code: PDA303T

Course Title:
Pharmacotherapeutics II

Course Leader: Mr. Subeesh K Viswam

subeesh.pp.ph@msruas.ac.in

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Course Details

Programme: Pharm D
Department: Pharmacy Practice
Head of the Department: Dr. E.Maheswari
Faculty: Pharmacy
Dean: Prof. (Dr.) V Madhavan (
dean.ph@msruas.ac.in)

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Course Aim and Summary

The aim of the Course is to impart the concepts of

molecular level chemical processes associated with
living cells for control, treatment and prevention of
diseases.

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Course Intended Learning Outcomes
After studying this Course, students will be able to:
1. Explain the etiopathogenesis of selected infectious
diseases, musculoskeletal and renal disorders
2. Discuss the principles of cancer therapy and
dermatological disorders
3. Identify the patientspecific parameters relevant in
initiating and monitoring drug therapy and adverse
effects
4. Discuss the therapeutic approach in the
management of selected diseases and controversies
in drug therapy
5. Prepare individualized therapeutic plans based on
diagnosis
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Faculty6. Recognise the role of pharmacistM. in
of Pharmacy essential
S. Ramaiah University of Appliedand
Sciences
 Course Content
Infectious disease: Guidelines for the
rational use of antibiotics and surgical
Prophylaxis, Tuberculosis, Meningitis,
Respiratory tract infections,
Gastroenteritis, Endocarditis, Septicemia,
Urinary tract infections, Protozoal
infection Malaria, HIV & Opportunistic
infections, Fungal infections, Viral
infections, Gonorrhoea and Syphillis
Musculoskeletal disorders: Rheumatoid
arthritis, Osteoarthritis, Gout, Spondylitis,
Systemic lupus erythematosus 5
Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Course Content (contd)
Renal system: Acute Renal Failure, Chronic Renal
Failure, Renal Dialysis, Drug induced renal
disorders
Oncology: Basic principles of Cancer therapy,
General introduction to cancer chemotherapeutic
agents, leukemia, Chemotherapy of breast
cancer, Leukemia. Management of chemotherapy
of Nausea and emesis
Dermatology: Psoriasis, Scabies, Eczema,
Impetigo

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Method of Assessment

There are two components for assessment in this

Course:

Component 1: 30% weight (CE)

Term Test: 30% Weight

Three tests (each of 30 marks) will be conducted

one at the end of 8 th week, second at the end of 16
th week and the third at the end of 24 th week, the
average of best two tests will be the marks scored
in term test and reduced to 15 marks. One
assignment for 30 marks will be reduced to 15
marks and a total of 30 marks (sessional and 7
Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Method of Assessment

Component 2 : 70% weight

A 3 hour duration year end examination will be
conducted for maximum marks of 70.
The assessment questions are set to test the
learning outcomes. The following table illustrates
the focus of learning outcome in each component
assessed

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Method of Assessment Contd..

Both components will be moderated by a second

examiner.

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 References
a. Essential Reading
1. Class Notes
a. Essential reading
1. Dipiro, T.J., Talbert, R.L., Yee, G.C., Matzke, G.R.,
Wells, B.G. and Posey, L.M. (2011)
Pharmacotherapy: A Pathophysiologic Approach. 8
th Edition, New York: Mc GrawHill.
2. Walker, R. and Whittlesea, C. (2007) Clinical
Pharmacy and Therapeutics. New York: Churchill
Livingstone publication

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Recommended Reading
1. Cotran, R.S., kumar, V. and Robbins S.L. (2005) Pathologic
Basis of disease. 7 th Edition, USA: W. B. Saunders
Company.
2. Green, R.J. and Harris, N.D. (2008) Pathology and
Therapeutics for Pharmacists: A basis for Clinical Pharmacy
Practice. UK: Pharmaceutical press.
3. Helms, R.A., Quan, D.J., Herfindal, E.T. and Gourley, D.R.
(2006) Textbook of Therapeutics: Drug and Disease
Management. 8 th Edition. Philadelphia: Lippincott Williams
and Wilkins Publication.
4. Kodakimble, M.A., Alldredge, B.K., Corelli, R.L., Ernst, M.E.,
Guglielmo, B.J., Jacobson, P.A., Kradjan, W.A. and Williams,
B.R. (2013) Applied Therapeutics: The Clinical use of
Drugs. 10 th Edition. Philadelphia: Lippincott Williams and
Wilkins Publication.
5. Speight, T.M. and Holford, N.H.G. (2011) Averys Drug 11
Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Disclaimer
Some of the contents of this Course has been
sourced from web sources and books.
REFERENCES -
www.Slideshare.com
www.googlescholar.com

The content is for education purpose

only

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture Delivered Additional
Date Time Topic
No. By Activity

Introductio
1 29-08-16 3-4pm n SKV
Role of
pharmacot
2 30-08-16 4-5pm herapeutics SKV GD
3 1/09/16 12-1pm Psoriasis SKV
4 2/09/16 4-5pm Psoriasis SKV
5 5/09/16 3-4pm Scabies SKV
6 6/09/16 4-5pm Class test SKV Tutorial
7 8/09/16 12-1pm Eczema SKV
8 9/09/16 4-5pm Eczema SKV
9 12/09/16 3-4pm Impetigo SKV
10 13/09/16 4-5pm Class test SKV Tutorial
Kidney
Function
11 15/09/16 12-1pm Test SKV
Kidney
Function
12 16/09/16 4-5pm test SKV
Acute Renal
13 19/09/16 3-4pm Failure SKV 13
Faculty of Pharmacy M. S.
M. S. Ramaiah University of Ramaiah Universit
Applied Sciences
 Delivered Additional
Lecture No. Date Time Topic
By Activity
numerical
problem
14 20/09/16 4-5pm Data Interpretation SKV solving
15 22/09/16 12-1pm Acute Renal Failure SKV
16 23/09/16 4-5pm Chronic Renal Failure
numerical
problem
17 26/09/16 3-4pm Data Interpretation SKV solving
Video
Demonstratio
18 27/09/16 4-5pm Dialysis SKV n
19 29/09/16 12-1pm Dialysis SKV
20 30/09/16 4-5pm Dialysis
21 04/10/16 4-5pm SKV
Drug Induced Kidney
22 06/10/16 12-1pm Failure SKV
23 07/10/16 4-5pm Principles of cancer
24 10/10/16 3-4pm Principles of cancer SKV
Video
Demonstrati
25 11/10/16 4-5pm Cancer on
26 13/10/16 12-1pm Principles of cancer SKV
27 14/10/16 4-5pm Principles of cancer SKV 14
M. S. Ramaiah
Faculty of Pharmacy Universit
M. S. Ramaiah University of Applied Sciences
 Lecture Delivered Additional
Date Time Topic
No. By Activity
Cancer
Chemotherapeu
28 17/10/16 3-4pm tic agents SKV
Cancer
Chemotherap
29 18/10/16 4-5pm eutic agents SKV Tutorial

30 20/10/16 12-1pm Breast Cancer SKV

31 21/10/16 4-5pm Breast Cancer SKV

32 24/10/16 3-4pm CINV SKV

33 25/10/16 4-5pm Breast cancer SKV Tutorial

34 27/10/16 12-1pm CLL SKV

35 28/10/16 4-5pm CML SKV

36 14/11/16 3-4pm RA SKV

37 15/11/16 4-5pm RA SKV

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Faculty of Pharmacy M. S.
M. S. Ramaiah University of Ramaiah Universit
Applied Sciences
 Lecture.1
Psoriasis

At the end of this lecture, student will be

able to

Explain pathophysiology of psoriasis

Describe clinical manifestations of psoriasis
Explain the etiology of psoriasis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture:2
Psoriasis

At the end of this lecture, student will be

able to

Explain different treatment options for psoriasis

Identify suitable lifestyle modification required for
psoriasis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 3
Scabies

At the end of this lecture, student will be

able to

Explain pathophysiology of scabies

Describe clinical manifestations of scabies
Explain the treatment of scabies

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 4
Atopic Dermatitis

At the end of this lecture, student will be

able to

Explain pathophysiology of atopic dermatitis

Describe clinical manifestations of atopic
dermatitis
Explain the etiology of atopic dermatitis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 5
Atopic Dermatitis

At the end of this lecture, student will be

able to

Explain different treatment options for atopic

dermatitis
Identify suitable lifestyle modification required for
atopic dermatitis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 6
Impetigo

At the end of this lecture, student will be

able to

Explain pathophysiology of impetigo

Describe clinical manifestations of impetigo
Explain the treatment of impetigo

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 7
Kidney Function Test
At the end of this lecture, student will be
able to

Summarize the different kidney function test

Interpret the kidney function test results

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 8
Kidney Function Test

At the end of this lecture, student will be

able to

Outline the physiology of kidney

Summarize the different kidney function test
Interpret the kidney function test results

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 9
Acute Renal Failure

At the end of this lecture, student will be

able to

Explain pathophysiology of acute renal failure

Describe clinical manifestations of acute renal
failure
Explain the etiology of acute renal failure

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 10
Acute Renal Failure

At the end of this lecture, student will be

able to

Explain different treatment options for acute renal

failure
Identify suitable lifestyle modification required for
acute renal failure

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 11
Chronic Renal Failure

At the end of this lecture, student will be

able to

Define chronic renal failure

Explain pathophysiology of Chronic renal failure
Explain the etiology of chronic renal failure

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 12
Chronic Renal Failure

At the end of this lecture, student will be

able to

Explain different treatment options for chronic

renal failure
Identify suitable lifestyle modification required for
chronic renal failure

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 13
Dialysis

At the end of this lecture, student will be

able to

Explain principle of dialysis

Describe different access points and their
advantages
Explain the indications of dialysis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 14
Dialysis

At the end of this lecture, student will be

able to

Explain different complications of dialysis

Identify suitable lifestyle modification required for
management of dialysis
Explain management of complications associated
with dialysis
Explain about peritoneal dialysis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 15
Drug Induced Kidney Disorders

At the end of this lecture, student will be

able to

Explain different drugs causing kidney injury and

their mechanism
Explain management of drug induced kidney
injury

30
Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 16
General Principles of cancer

At the end of this lecture, student will be

able to

Explain etiology of cancer

Describe metastasis
Explain classification of cancer

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 17
Cancer Chemotherapy

At the end of this lecture, student will be

able to

Explain different treatment modalities in cancer

chemotherapy

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 18
Cancer Chemotherapy

At the end of this lecture, student will be

able to

Explain different treatment modalities in cancer

chemotherapy

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 19
Chemotherapeutic Agents

At the end of this lecture, student will be able to

Describe different chemotherapeutics agents and their

characteristics

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 20
Breast Cancer

At the end of this lecture, student will be

able to

Explain pathophysiology of breast cancer

Describe clinical manifestations of breast cancer
Explain the etiology of breast cancer

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 21
Breast Cancer

At the end of this lecture, student will be

able to

Explain management of breast cancer

Describe lifestyle modification adopted for
management of breast cancer

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 22
Chemotherapy Induced Nausea and
Vomiting
At the end of this lecture, student will be
able to

Explain different treatment options for

chemotherapy induced nausea vomiting

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 23
Chronic Lymphocytic Leukemia

At the end of this lecture, student will be

able to

Explain pathophysiology of Chronic lymphocytic

leukemia
Describe clinical manifestations of Chronic
lymphocytic leukemia
Explain the etiology of Chronic lymphocytic
leukemia
Explain the management of Chronic lymphocytic
leukemia
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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 24
Chronic Myeloid Leukemia

At the end of this lecture, student will be

able to

Explain pathophysiology of Chronic myeloid

leukemia
Describe clinical manifestations of Chronic
myeloid leukemia
Explain the etiology of Chronic myeloid leukemia
Explain the management of Chronic myeloid
leukemia

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 25
Rheumatoid Arthritis

At the end of this lecture, student will be

able to

Explain pathophysiology of Rheumatoid Arthritis

Describe clinical manifestations of Rheumatoid
Arthritis
Explain the etiology of Rheumatoid Arthritis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences
 Lecture 26
Rheumatoid Arthritis

At the end of this lecture, student will be

able to

Explain different treatment options for rheumatoid

arthritis
Identify suitable lifestyle modification required for
rheumatoid arthritis

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Faculty of Pharmacy M. S. Ramaiah University of Applied Sciences