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  • HEMATOPOESIS

    Diunggah oleh

    Atika Najla
    37 tayangan13 halaman
    The document summarizes hematopoiesis and common types of anemia found in Indonesia. It describes the stem cell origins of red blood cells, white blood cells, platelets, and their development lineages. It then covers parameters for hematology tests, characteristics of different anemia types based on morphology and etiology, and laboratory tests used to evaluate specific anemias like iron deficiency, hemolytic, and megaloblastic anemias. Finally, it lists some frequently encountered anemias in Indonesia such as iron deficiency anemia, anemia of chronic disease, folate deficiency megaloblastic anemia, and beta-thalassemia.

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    The document summarizes hematopoiesis and common types of anemia found in Indonesia. It describes the stem cell origins of red blood cells, white blood cells, platelets, and their development lineages. It then covers parameters for hematology tests, characteristics of different anemia types based on morphology and etiology, and laboratory tests used to evaluate specific anemias like iron deficiency, hemolytic, and megaloblastic anemias. Finally, it lists some frequently encountered anemias in Indonesia such as iron deficiency anemia, anemia of chronic disease, folate deficiency megaloblastic anemia, and beta-thalassemia.

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    37 tayangan13 halaman

    HEMATOPOESIS

    Diunggah oleh

    Atika Najla
    The document summarizes hematopoiesis and common types of anemia found in Indonesia. It describes the stem cell origins of red blood cells, white blood cells, platelets, and their development lineages. It then covers parameters for hematology tests, characteristics of different anemia types based on morphology and etiology, and laboratory tests used to evaluate specific anemias like iron deficiency, hemolytic, and megaloblastic anemias. Finally, it lists some frequently encountered anemias in Indonesia such as iron deficiency anemia, anemia of chronic disease, folate deficiency megaloblastic anemia, and beta-thalassemia.

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    dari 13

    HEMATOPOESIS

    Eritropoesis

    Eritrosit
    Sel Induk
    Multi Potensial Granulopoesis Granulosit

    Sel Induk Monosit


    Pluri Potensial Megakaryositopoesi

    Trombosit

    Limposit T

    Sel Induk Limpopoesis


    Limfoid Limposit B

    1
    HEMATOPOESIS PADA EMBRIO

    YOLK SAC

    SST

    LIVER
    HEPATIK MYELOID

    SPLEEN
    MESOBLASTIK LYMPHNODE

    1 2 3 4 5 6 7 8 9 10
    ASAL USUL DARAH

    Monophyletic Teori Reticulo Endothelium Undiff Mesenchym


    ( Maxiwon ) Hemo Histioblast
    Myeloblast ( Hemocytoblast )

    Polyphyletic Teori Mesoderm ( Embrio ) Toti Potensial


    ( Naegelietal ) Mesenchym & Endothelium Multi Potensial
    1. Extra Vasculer Origin Mesenchym Multipotent - Myelobalst
    - Monobalst
    -Lympobalst
    2.Intra Vaskuler Origin Endothel Duo Potent - Erythroblast
    - Histiocyte
    3.Intra & Extra
    PARAMETER DASAR
    HEMATOLOGI

    1.Hb ( Lk 14 16 gr % ) 3. Ht
    ( Pr 12 14 gr % ) 4.Lekosit
    2.Eritrosi 5.Trombosit
    Ht
    MCV = x 10 = 85 10 fl
    Eri
    Hb
    MCH = x 10 = 29,5 2,5 pg
    Eri
    Hb
    MCHC = x 100 % = 32,5 2,5 %
    Ht
    Anemia ( Morfologis )

    Macrositer Hyperchrom
    Normositer Normocrom
    Micrositer Hypochrom

    Defisiensi : Fe, Folat , Vit B 12


    Hemolitik
    Anemia
    ( klinis ) Hemorrhagik
    Aplastik
    PEMERIKSAN BAHAN KHUSUS

    ANEMIA DEFF Fe

    Serum Iron
    TIBC
    Saturation Transferin
    Ferritin
    Serum Transferin
    Hemosiderin Urine, SST
    ANEMIA HEMOLITIK
    Hb Plasma Elektroforese
    Hb F
    Sugar water Test
    Hams Test
    Resistensi Osmotik
    Coombs Test Direct & Indirect
    Spesifik Antibodi
    Ig G, M, A, D.
    Serum Protein
    Monoklonal Antibodi
    Vit B12 Serum , Folat Serum
    Eritrosit Life Span
    Reticulocyte Count
    G6PD & Enzim Eritrosit
    BMP & Biopsi
    HEMATOPOETIK STEM SEL
    ANEMIA NORMOKROM NORMOSITER

    Anemia Normokrom Normositer

    Retikulosit ( N ) / Menurun

    Ax, Fx, Hapusan Darah Bilirubin BMA / Biopsi

    Anemia Hemolitik Perdarahan Akut

    BM : (Abn ) BM : ( N )

    Aplastik Infiltrasi DMPS TF Ginjal TF Hati TF Endkr Serum

    Leukemia, mieloma CRF Anemia Myxedema Anemia


    Mielofibrosis, metastase peny hati Addison Peny kronik
    ANEMIA HIPOKROM MIKROSITER

    Anemia Hipokrom Mikrositer

    Serum Fe

    Menurun (N) Meningkat

    Fe Sutul Ferritin

    Elektroforese Hb dsb Fe Sutul meningkat


    ( Sideroblast )
    ( - ) Def Besi Rendah
    Anemia Sideroblastik
    Anemia ( N ) / ( ? ) Thalasemia
    Penyakit Kronik Hb pati Kongenital
    di dapat
    ANEMIA YANG SERING DI JUMPAI DI
    INDONESIA
    ANEMIA DEFISIENSI BESI
    ANEMIA INFLAMASI
    ANEMIA MEGALOBLASTIK ( DEF ASAM FOLAT )
    ANEMIA HEMOLITIK
    - THALASEMIA
    OBAT OBATAN
    ANEMIA ec INSUFISIENSI RENAL
    ANEMIA GRAVIDARUM

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