A. Catalase
B. Coagulase
C. *Protein A
D. Teichoic acid
2. The main reason why methicillin-resistant Staphylococcus aureus
(MRSA) strains are resistant to methicillin and nafcillin is:
A. coagulase.
B. enterotoxin.
C. exfoliatin.
D. *P-V leukocidin.
4. An outbreak of serious pneumococcal pneumonia and sepsis among
inmates in an overcrowded prison has occurred. Laboratory analysis
determined that one serotype was involved. The prison physician said
that the pneumococcal vaccine might have limited the outbreak. Which
one of the following structures of the pneumococcus is responsible for
determining the serotype and is also the immunogen in the vaccine?
A. *Capsule
B. Flagellar protein
C. O antigen
D. Peptidoglycan
5. Which one of following laboratory tests is the most appropriate to
distinguish Streptococcus pyogenes from other -hemolytic
streptococci?
A. Enterococcus faecalis
B. *Staphylococcus aureus
C. Staphylococcus epidermidis
D. Streptococcus agalactiae
7. Your patient is a 2-week-old infant who was well until 2 days ago, when
she stopped feeding and became irritable. She now has a fever to 380C,
developed a petechial rash all over her body, and is very difficult to arouse.
In the emergency room, a blood culture and a spinal tap were done. Gram
stain of the spinal fluid showed gram-positive cocci in chains. Culture of the
spinal fluid on blood agar revealed -hemolytic colonies that grew in the
presence of bacitracin and hydrolyzed hippurate. Which one of the
following is the most likely causative organism?
A. Staphylococcus aureus
B. *Streptococcus agalactiae
C. Streptococcus pneumonia
D. Streptococcus pyogenes
8. Your patient is a 70-year-old man with endocarditis caused by
Enterococcus faecalis. Which one of the following is the best combination
of antibiotics to treat the infection?
A. Skin
B. Colon
C. *Oropharynx
D. Urethra
10. The coagulase test, in which the bacteria cause plasma to clot, is
used to distinguish:
A. Protein A
B. *Capsule
C. Endotoxin
D. Beta-Lactamase
13. Each of the following statements concerning gonorrhea is correct
EXCEPT:
A. *Endotoxin
B. IgA protease
C. Oxidase
D. Superantigen
15. Disease caused by which one of the following sets of bacteria can be
prevented by a toxoid vaccine?
A. *Bacillus anthracis
B. Clostridium botulinum
C. Clostridium perfringens
D. Listeria monocytogenes
17. An abattoir worker developed pustule which later progress to
necrotic ulcer. Which of the following stain is useful demonstration of
organism from smear made from pustule ?
A. Cl. tetani
B. Cl. botulinum
C. *Cl. perfringenes
D. Cl. septicum
20. A 12 year old child presents with fever and cervical lymphadenopathy.
Oral examination shows a grey membrane on the right tonsil extending to
the anterior pillar. Which of the following medium will be ideal for the
culture of the throat swab for a rapid identification of the pathogen :
A. Nutrient agar
B. Blood agar
C. *Loefflers Serum slope
D. LJ Medium
21. The genetic mechanism responsible for the conversion of a
nontoxigenic strain of Corynebacterium diphtheriae to a toxigenic strain
is
A. Herd immunity
B. *Prognosis
C. Treatment
D. Epidemological investigations
23. Your patient is a 25-year-old homeless man who complains of a cough for the
past month. The cough is now productive of several tablespoons of bloodstreaked
sputum per day. The sputum is not foul-smelling. He has lost 10 pounds but says
that he doesnt eat regularly. On physical exam, temperature is 38C, and coarse
rales were heard in the apex of the left lung. An acid-fast stain of the sputum
reveals acid-fast rods. Culture of the sputum shows no growth at 7 days, but buff-
colored colonies are visible at 21 days. Of the following organisms, which one is
most likely to be the cause of this infection?
A. Mycobacterium fortuitum-chelonae
B. Mycobacterium leprae
C. Mycobacterium marinum
D. *Mycobacterium tuberculosis
24. True about M. tuberculosis is :
A. *Strict aerobe
B. Gram negative
C. Thin cell wall
D. Curved rod
25. In TB, immunity is provided by :
A. *CD 4+ T cells
B. CD 8+ T cells
C. IgG
D. IgM