ESC/ESH guideline The relationship between BP & risk of CVD events is continuous, consistent, & independent of other risk factors. The higher the BP, the greater the chance of heart attack, HF, stroke, and kidney diseases. Evaluation of hypertensive patients has 3 objectives: 1. To assess lifestyle & identify other cardiovascular risk factors or concomitant disorders that may affect prognosis & guide treatment
2. To reveal identifiable causes of high BP
3. To assess the presence or absence of
target organ damage & CVD. Terapi ESC/ESH 2013 JNC 8 JNC 8 JNC 8 JNC 8 Green continuous lines: preferred combinations; green dashed line: useful combination (with some limitations); black dashed lines: possible but less well tested combinations; red continuous line: not recommended combination. Hypertensive Crises: Emergencies & Urgencies Hypertensive emergencies
Severe elevations in BP (>180/120 mmHg)
Hypertensive urgencies Complicated by evidence of impending or progressive target organ dysfunction Severe elevations in BP without progressive target Require immediate BP reduction (not organ dysfunction. necessarily to normal) to prevent or limit target organ damage Examples: upper levels of stage II hypertension Examples: hypertensive encephalopathy, associated with severe intracerebral hemorrhage, acute MI, acute headache, shortness of left ventricular failure with pulmonary breath, epistaxis, or severe edema, unstable angina pectoris, dissecting anxiety. aortic aneurysm, or eclampsia. Hypertensive Emergencies
should be admitted to ICU: monitoring of BP
& parenteral administration BP : MAP <25% (within minutes to 1 hour) Excessive falls in pressure that may precipitate renal, cerebral, or coronary Clinically stable ischemia should be avoided short-acting nifedipine is no longer considered BP 160/100110 mmHg acceptable within the next 26 hours
Exceptions to the recommendation:
Clinically stable ischemic stroke patients aortic dissection who should have their further gradual reductions SBP lowered to <100 mmHg if tolerated toward a normal BP in the patients in whom BP is lowered to next 2448 hours enable the use of thrombolytic agents Hypertensive Urgencies
May benefit from treatment with an oral, short-
acting agent such as captopril, labetalol, or clonidine followed by several hours of observation.
Should not leave the ER without a confirmed follow