Anatomy
R.Arulmoli
Learning outcomes
1.Prokaryotic cells -
Cells without true nucleus. Example: Bacteria.
Smaller in size than eukaryotic cells.
2.Eukaryotic cells -
Cells with nucleus.Example: Animals, plants and
fungi.
Cell : Structure
Cytoplasm :
Located between the cell membrane
and nuclear membrane.
2 sub-divisions:
1.Cytosol or intracellular fluid:
Dissolved nutrients, ions,
soluble & insoluble proteins,
and waste products
2. Organelles:
Structures which perform
specific functions.
Cellular organelles
1. Non-membranous organelles
Cytoskeleton
Micro villi
Cilia
Ribosome
Centrioles
2. Membranous organelles
Endoplasmic reticulum-smooth and rough
Golgi apparatus
Lysosomes
Perioxisomes
Mitochondria
3. Nucleus
Cell : Structure
Cell : Structure
Cell membrane or plasma membrane
Membrane Lipids:
Phospholipids,
Bilayered,
Hydrophobic.
Membrane Proteins:
Integral proteins Trans membrane proteins.
Peripheral proteins inner or outer surface.
Membrane Carbohydrates:
Proteoglycans, glycoproteins, glycolipids.
Glycocalyx.
Membrane permeability
Permeability:
Impermeable
Permeable
Selectively permeable
Energy requirement:
Active permeability
Passive permeability
Transport process:
Diffusion
Filtration
Carrier-mediated transport
Vesicular transport
Membranous organelles
Endoplasmic reticulum
Structure-
- Outer and inner membrane.
- Numerous folds called
cristae (increases the
surface area of the
matrix of the
mitochondria)
Power house of a cell by
producing ATP.
Requires oxygen for its
activity aerobic
metabolism.
Mitochondrial DNA
yeast
Human: 16 kb
Yeast: 84 kb
Corn: 570 kb
human
Mitochondrial DNA
Ovum contains 23
chromosomes and cell
cytoplasm which
contains thousands of
maternal mitochondria.
Sperm contains 23
chromosomes with very
little cytoplasm.
Why mom?
DNA is in Chromatin
Structure of a
Eukaryotic
Nucleus
Chromosomes and DNA
Chromosomes are
present inside the
nucleus.
46 chromosomes,
combination from both
parents; 23
chromosomes from each
parent.
Chromosomes and DNA
DNA: Chemical composition
Yeast 12 Mb 6000
Genes and genomes
ANIMAL CELL
PLANT CELL
Dr. Craig Venter and Dr. Hamilton Smith from Craig Venter
Institute, California, USA, announced on 20 May 2010 the first
synthetic cell.
It is synthetic because the cell is totally derived from a synthetic
chromosome.
Applications:
To investigate how life works.
To create bacteria designed for the production of bio fuels and
cleaning the environment.
Working on ways to speed up vaccine production.
Cell division
Mitosis
The paired
chromosomes separate
at the kinetochores and
move to opposite sides
of the cell.
Telophase
Chromatids arrive at
opposite poles of cell,
and new membranes
form around the
daughter nuclei.
The chromosomes
disperse.
The spindle fibers
disperse, and
cytokinesis or the
partitioning of the cell
may also begin during
this stage.
Cytokinesis
Chiasmata separate.
Chromosomes, each with
two chromatids, move to
separate poles.
Each of the daughter cells
is now haploid (23
chromosomes), but each
chromosome has two
chromatids.
Telophase I
Analogous to mitosis
where two complete
daughter cells form.
Meiosis II
Cell membrane
Endoplasmic reticulum
Ribosomes
Golgi apparatus
Lysosome
Mitochondria
Nucleus