PERNAFASAN
Nasal Polyp
Inflammation
• Acute
• Chronic
Neoplasm
• Juvenile angiofibroma
• Undifferentiated carcinoma
a McIvor mouth gag is applied and a left nasopharyngeal
mass is visible behind the soft palate and left posterior
pillar. The final diagnosis was lymphoepithelioma
Nasopharingeal Ca, non-keratinizing, undiff.
Nasopharingeal Ca, non-keratinizing, undiff.
EBV
(IH; LMP-1) x 600
Anaplastic (undifferentiated)
Carcinoma
Metastasic tumor
LARYNX: benign vs malignant
Laryngeal papillomatosis
Laryngeal Carcinoma
Histological classification
Primary tumors
• Bronchogenic tumors
• Non-bronchogenic tumor
Secondary tumors (metastasis)
Carcinoma in situ: bronchus
Carcinoma in situ: bronchus
Carcinoma in situ: bronchus
The incidence of the bronchogenic
tumors
1. Non-small cell lung Ca (NSCLC): 70-75%
a. SCC: 25 – 30 %
b. AdenoCa, including bronchioloalveolar
carcinoma: 30 – 35 %
c. Large cell Ca: 10 – 15 %
2. Small Cell Lung Ca (SCLC) : 20 – 25 %
3. Combined : 5 – 1 0 %
- SCC + adenoCa
- SCC + SCLC
lung carcinoma
c d
a. Squamous cell ca.: men >> women, smoking history
central bronchus
squamous metaplasia-displasia-Ca
a. Sputum specimen
b. FNA of Lnn : small cell ca
Bronchioloalveolar carcinoma
SCC in situ with foci of early invasion (nodular Early invasive scc
thickening)
SCC
Endobronchial SCC
Well differentiated SCC
Keratin mass
SCC moderately differentiated
Pearl formation
Pearl formation
Mesothelioma
Pleural mesothelioma
Epithelial mesothelioma
Sarcomatous mesothelioma
Lymphnode stations
Alveolar soft part sarcoma, well circumscribed Irregular border: a nodule of metastatic leio-
with pushing border. Metastases often have myosarcoma extends into the interstitium of
this appearance. the surrounding lung
Pattern of Metastasis
Multinodular metastasis
Yellow appearance to the metastatic nodules: Black appearance in some nodules: primary
abundant fat content of primary tumor: renal- Tumor is malignant melanoma
cell carcinoma
Pattern of Metastasis
“Cannonball” metastasis