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Source Target Actions Factors that
tissue Stimulate
Release

Produced in Distal Increases Low fluid intake

hypothalamus convoluted permeability of decreases blood
-released by tubule and the collecting volume and
posterior collecting ducts to water, increases
pituitary ducts increasing osmotic
gland reabsorption pressure of
and decreasing blood; receptors
water excretion in hypothalamus
stimulate
posterior
pituitary
{
our blood will have a low
water potential (becomes more
concentrated)

2 his is detected by
osmoreceptors in your
hypothalamus, which stimulates
pituitary to release
antidiuretic hormone (ADH)
^ he release of ADH into the bloodstream brings
about the following:

u ADH makes the distal convoluted

tubule and collecting duct more
permeable to water

u his allows more water to be

reabsorbed from distal convoluted
tubule and collecting duct into the
region of high solute concentration in
the medulla
áhisproduces a smaller
volume of more
concentrated urine

áInaddition to stimulating
the release of ADH when
the blood concentrated,
the hypothalamus also
activates your thirst
centre in the brain
áAs a result, you feel thirsty and
take in additional water to dilute
the blood

áDrinking stops the stimulating of

your thirst center almost
immediately

áhis is though to be due to the

thirst centre responding to the
stomach filling water
{
our blood will have a high
water potential (it become
more dilute)

2 his is detected by the

osmoreceptors in your
hypothalamus and results
in a decrease in the
amount of ADH secreted
by the pituitary
^ he decrease in the amount of ADH in
the bloodstream results in the
following:

á Lack ADH makes the distal convoluted

tubule and collecting duct less
permeable to water

á Less water is reabsorbed into the

medulla

á Larger quantities of dilute urine are

produced