Presented by
Mr. Prashant Gaikwad
Under Guidance of
Dr. A Srinatha
• The Usp-NF provides several official methods for
carrying out dissolution test.
1. Closed-compartment apparatus
3. Dialysis apparatus
Factors must be considered in design of
dissolution tests:
1. Factors relating the dissolution apparatus
1. A covered vessel
• Cylindrical, hemispherical bottom
• Diameter is 98-106 mm & normal capacity 1000 ml
3. Cylindrical basket
• Gold coating 0.0001 inch (2.5 µm)
Apparatus 2 (Paddle)
holder
– Motor & drive assembly
• Reciprocate at frequency of
about 30 cycles/min.
Rotating Bottle
• Used for controlled release beads
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