AND
PNEUMOTHORAX
By:
WIDIRAHARDJO
inspiration expiration
PHYSIOLOGY OF THE PLEURAL SPACE
(contd)
exudative transudative
Tuberculosis Congestive heart
Tumor Nephrotic syndrome
Pneumonia Cirrhosis hepatis
Trauma Meig’s syndrome
Collagen disease Hydronephrosis
Asbestosis Peritoneal dialysis
Uremia
Radiation
Sarcoidosis
Emboli
TRANSUDATIVE PLEURAL EFFUSION
Pathogenesis:
- sequel to a primary tuberculous infection
(post primary infection)
- reactivation
- result from rupture of subpleural caseous
focus in the lung
- delayed hypersensitivity
TUBERCULOUS PLEURAL EFFUSION
(contd)
Clinical manifestation:
- most common as an acute illness: < 1
week
- cough, usually nonproductive
- chest pain, ussually pleuritic
- fever
- younger than patients with parenchymal
tb
- usually unilateral and can be of any size
TUBERCULOUS PLEURAL EFFUSION
(contd)
Diagnosis:
1. Spontaneous pneumothorax
occur without antecedent trauma or other obvious cause,
devided into:
• Primary spontaneous pneumothorax (PSP): occur in
healthy individuals
• Secondary spontaneous Pneumothorax (SSP): occur as a
complication of underlying lung disease, most commonly
COPD (chronic obstructive pulmonary disease).
PNEUMOTHORAX
2. Traumatic pneumothorax:
occur as a result of direct or indirect trauma to
the chest:
3. Iatrogenic pneumothorax: occur as a an
intended or inadvertent consequence of a
diagnostic or therapeutic maneuver.
PRIMARY SPONTANEOUS PNEUMOTHORAX
(PSP)
INCIDENCE
Males: 7,4/100.000 per year
Females: 1,2/100.000 per year
Relative risk in smoker 7-102 times higher
Usually taller and thinner, associate with genetical
predisposed to bleb formation
Peak age of the occurrence is in the early 20s
Rare after age 40
PRIMARY SPONTANEOUS PNEUMOTHORAX
PATHOPHYSIOLOGY
The negative/ sub atmospheric
pressure of the pleural space and
The positive pressure of the alveolar
pressure always positive
Develop of communication between
alveolus and pleural space
Air flow from alveolus into pleural
space
PRIMARY SPONTANEOUS PNEUMOTHORAX
CLINICAL MANIFESTATION
The main symptom: chest pain and dyspnea
DIAGNOSIS:
= Clinical history
= Physical diagnostic
= Chest x-ray: is a definitive diagnostic,
showed the visceral pleural line. Expiratory
films are more sensitive than are inspiratory
films.
QUANTITATION:
PRIMARY SPONTANEOUS PNEUMOTHORAX
RECURENCE RATE:
= Without thoracotomy: 52%, 62% and 83% in
patient had first, second and third
pneumothoraces respectively
= Chest CT may predict the recurrence, where
the individual with numerous and the largest
bullae would be most likely had recurrence
TREATMENT
A. Observation
= Resorbed of the air in the pleural space about
1,25% per day, if the communication between
the alveoli and pleural space is eliminate
= Bed rest
B. Supplemental Oxygen
= Supplemental oxygen: increased the rate of air
absorption until 6 time
= As a routine treatment for all type of
pneumothorax
TREATMENT
C. Aspiration
= As a initial treatment for psp > 15%
= By G-16 needle with internal
polyethylene catheter, inserted into
anterior 2nd ICS at mid clavicle line after
local anesthesia, a three way stopcock
and 60ml syringe
= 64% successful
= Tube thoracostomy for unexpanded lung
TREATMENT
D. Tube thoracostomy
= Permits the air to be evacuated effectively
and rapidly
= Connected to underwater seal, low
pressure continuous suction (up to
100cmH2O), or to a Heimlich valve
E. Pleurodesis
= Instilation of any sclerosing agent to the pleural
space or by abrasion to create obliteration of the
pleural space
TREATMENT
F. Thoracoscopy
= Direct view to the entire thoracic cavity
= To treat the bullous disease responsible
for the pneumothorax
= To create a pleurodesis
G. Thoracotomy
= For patient who fail to previous
treatment
SECONDARY SPONTANEOUS
PNEUMOTHORAX (SSP)
SSP are more serious than PSP, because
decreased the lung function of patient withy
already compromised lung function
INCIDENS: 6,3/100.000/year (US)
ETIOLOGIC FACTORS:
= COPD
= TB
= Asthma
= Pneumonia
= Lung cancer
SECONDARY SPONTANEOUS
PNEUMOTHORAX
CLINICAL MANIFESTATIONS:
= More severe than PSP
= Mostly: dyspnea, chest pain, cyanosis,
and hypotension
= Mortality: 16%, is associated with
respiratory failure
= Recurrent rate: 44%
= PD: similar to PSP, but less helpful,
especially for patient with COPD
SECONDARY SPONTANEOUS
PNEUMOTHORAX
DIAGNOSIS: established by chest x-ray, show of a
visceral pleural line. Must differentiation from
large bulla, if any doubt, CT thorax may be done.
TREATMENT:
The goals are to rid the pleural space of air
and to decreased a recurrence; treatment are
the same as PSP, except the aspiration is a limited
role in SSP.
MADE IN ENGLAND
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MADE IN INDONESIA
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