DENTAL LAMINA Prepared By:

Nur Amira Illani binti Roslan

AND ITS FATE I BDS 2016/17

INTRODUCTION
 The stomatodeum, or also known as the primitive oral cavity, is
lined by stratified squamous epithelium called the oral ectoderm.
 This oral ectoderm contacts the endoderm of the foregut to form
the buccopharyngeal membrane.
 At about the 3rd weeks of gestation, this membrane ruptures.
 This allows the connection of stomatodeum with the foregut.
 Following this, the development of tooth is thought to be initiated
by the interaction between epithelium and connective tissue.
 Lining of Development
Ruptures at 27th day
stomatodeum comes of tooth
of gestation
in contact with foregut
 START
 Tooth development
starts from the anterior
region, of both
maxillary and
mandibular arch, END END

 before proceeding
posteriorly.
START
 The first sign of tooth development is denoted,
when there is a presence of
condensation of ectomesenchymal cells, beneath
the epithelium and the future tooth bearing regions.
These condensed ectomesenchymal cells induces the
overlying epithelium to proliferate, forming an
epithelial thickening called
the Primary Epithelial Band
 Primary
6of thintrauterine
week life
Epithelial
Band

Lingual Buccal
th
7 week Extension Extension
of intrauterine life (facing tongue) (facing lip
and cheek)

Dental Vestibular
Lamina Lamina
 Future tongue

Lip
 Tongue

Tooth
bearing area

Vestibule
6ofthintrauterine
week life
Primary
Epithelial Band

7 th week Lingual Buccal

Extension Extension
of intrauterine life

Vestibular
Dental Lamina Lamina

After formation of deciduous teeth buds

Distal Lingual Oral
proliferation extension Degenerates
vestibule

Germs of Germs of other Remnants of

permanent permanent cell rests of
molars teeth serres
VESTIBULAR LAMINA
Vestibular lamina proliferates
into ectomesenchyme, and
undergoes degeneration to form
the vestibule.

Vestibule separates lips and

cheeks from tooth bearing area.
DENTAL LAMINA
During the 7th week of intrauterine
life, dental lamina proliferates into
the underlying ectomesenchyme

Forming U shaped band, along

with the dental arch in the future

This acts as the primordium for the

enamel organ of the deciduous
teeth.
 Ectodermal
Differential gives rise to component of 10
proliferation at 10 deciduous teeth in
specific regions each arch.
 Successors of deciduous teeth
develop from the lingual
extensions (successional lamina),

 Whereas permanent molars

develop from the distal
extensions (accessional lamina).
FATE OF DENTAL LAMINA
 As tooth development proceeds, dental lamina will degenerate as
it will be no longer needed.
 The average activity of dental lamina is about 5 years.
 However, few remnant cells called ‘Cell rests of Serres’ may
remain even after the degeneration of dental lamina.
 In the future, under certain conditions, these unwanted
proliferation of cells may give rise to cysts or tumours.
THE EMERGENCE OF CELL REST OF SERRES
BUD STAGE

Oral ectoderm

Dental lamina

Enamel organ
CAP STAGE
BELL STAGE
BELL STAGE
BELL STAGE
BELL STAGE

Cell rests of Serre

CYSTS AND TUMOURS ORIGINATED FROM
CELL REST OF SERRE
Cell Rest of
Serres

Cysts Tumours

Odontogenic keratocyst Ameloblastoma

Lateral periodontal cyst
Gingival cyst
Glandular odontogenins cyst
Squamos odontogenic tumour
Calcifying epithelial odontogenic
tumour
Adenomatois odontogenid tumour
Odontogenic
keratocyst
Ameloblastoma

Gingival cyst
Glandular odontogenins cyst Squamos odontogenic tumour
SUPERNUMERARY TEETH
 It is suggested that supernumerary teeth develop from a third bud
arising from the dental lamina near the regular tooth bud.
 This happens when dental lamina fails to degenerate and thus it continue
to induce the formation of tooth bud.
REFERENCES
 G S Kumar: ORBAN’s Oral Histology & Embryology, Reed Elsevier India
Private Limited – 14th edition.

 Maji Jose: Essentials of Oral Biology – Oral Anatomy, Histology,

Physiology & Embryology, CBS Publishers & Distributors Pvt. Ltd, Reprint
edition 2014.

 Daniel J. Chiego Jr: Essentials of Oral Histology & Embryology, Reed

Elsevier India Private Limited – 4th edition.
THANK YOU! 