Penyembuhan luka

Hendy Buana Vijaya

Fasilitator :
 Wound
• An acute wound is a wound for which the injury has occurred within the
past 3 to 4 weeks.
• If the wound persists beyond 4 to 6 weeks, it is considered a chronic
wound, a term that also includes wounds that have been present for months
or years. “Non-healing, recalcitrant,” and “delayed healing” are terms used
interchangeably to describe chronic wounds.
 Skin

• Lapisan epidermis : stratum korneum, stratum

lusidum, stratum granulosum, stratum spinosum, dan
stratum basale.
• Lapisan dermis (korium, kutis vera, true skin) adalah
lapisan di bawah epidermis, dibagi menjadi dua bagian
yaitu pars papilare dan pars retikulare.
• Lapisan subkutis (hipodermis) adalah kelanjutan
dermis, terdiri atas jaringan ikat longgar berisi sel-sel
lemak didalamnya.
Factor influence of wound healing

Ischmia Infection Foreign body

Edem/Elevated
tissue pressure
Factor influence of wound healing

Diabetes Fetal Wound

Age
mellitus Healing

Hypothermia
Sepsis
and pain
Factor influence of wound healing

Spesific organ
Nutrition Corticostreroids
failure

Ionizing
Radiation and
Chemotherapy
Phase of wound
healing
Biologically moleculs
 Inflammation

• Begin when the wound

develop
• Marked by rubor, tumor,
calor, dolor
• Healing process
• Immune system work
 Proliferation

• Grannulation tissue filled the

wound
• Fibroblast lay collagen
• Wound edges begin to
contract
• Epithelial cell migrates from
wound margin
 Remodeling

• from 21 days up to
1 year
• Once the wound has been
“filled in” with granulation
tissue and after keratinocyte
migration has re-
epithelialized
it, the process of wound
remodeling occurs
Terima kasih