For Vertigo
(Based on EBM)
Level of Evidence for Therapetic Study
prognostic
Original Reseach
Methode
90 patient
• Objectives :
To assess the effects of betahistine in
patients with symptoms of vertigo from
different causes.
Methode
• The Cochrane ENT Information Specialist
searched the Cochrane ENT Trials Register;
Central Register of Controlled Trials (CENTRAL
2015, Issue 8); PubMed; EMBASE; CINAHL; Web
of Science;
• ClinicalTrials.gov; ICTRP and additional sources
for published and unpublished trials. We also
contacted manufacturers and researchers in the
field.
• The date of the search was 21 September 2015.
Selection criteria
Vasolitasi pembuluh
Agonis B1
darah otak
Vertikaf
(Betahistin)
histamine, acetylcholi
Agonis B3 ne, norepinephrine, s
erotonin, and GABA
Conclution
• Betahistin has benefit for vertigo treatment
• Combination betahistin and eplye manouvre better
than betahistin alone, specially for BPPV treatment
• Betahistin has limited for prevention attact vertigo
caused by menier disease
• Vestibular rehabilitation give improve vertigo
• High Dose More effective for Vertigo Treatment
• High Dose is betahistine is safe.
• Terima Kasih