Cardiac disturbances
GI symptoms
Anorexia, N/V/D, abdominal pain
CNS effects
Weakness, blurred vision, halos around light
In severe cases can cause hyper K
Can be difficult to detect clinically
In Dig trial incidence of “Digoxin toxicity” was 11.9% in Digoxin group
and 7.9% in placebo group
Conduction Defects in Digoxin Toxicity