LEU

KEM
IA
 DEFINITION
 Leukemia is a cancer of blood. It is a group of
malignant disorders affecting the blood and tissue
forming the blood such as:
 Bone marrow
 Lymph system
 Spleen
 Leukemic cells replace white blood cells and
makes the body very weaker and vulnerable to
any infection

 Leukemia may affect females and males of all

age groups
TYPES OF LEUKEMIA

 Acute
 Acute Lymphoblastic Leukemia(ALL)
 Acute Myeloid Leukemia(AML)

 Chronic
 Chronic Myeloid Leukemia(CML)
 Chronic Lymphocytic Leukemia(CLL)
DIFFERENCES BETWEEN ACUTE
AND CHRONIC LEUKEMIA
ACUTE
Progress rapidly
Severely ill
Heals without complication
Common in younger age
groups
Need immediate treatment
It is prominent
Prognosis is predictable
Normal growth factor levels
Normal level of inflammatory
cytokines
CHRONIC
Progress slowly
Can be asymptomatic
Complication arises
Common in older age groups
Treatment can be delayed
It is mild
Prognosis is unpredictable
Lower growth factor levels
Increased level of pro
inflammatory cytokines
PATHOPHYSIOLOGY
 ETIOLOGY
 Heredity
 Environmental factors
 Infections
 Consumption of alcohol
and drugs
 Smoking
 Radiation exposure
 Association with diseases
of immunity
DIAGNOSIS
Blood test
Bone marrow test
Biopsy
Physical test
Blood cell examination
Cytogenetic
 TREATMENTS
 Chemotherapy
 Biological Therapy
 Targeted Therapy
 Radiation Therapy
 Stem Cell Therapy
 Watchful Waiting
 Bone Marrow Transplantation
 GRAPH REPRESENTING
PERCENTAGE OF LEUKEMIA
PATIENTS BASED ON AGE