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HERPES ZOSTER

Olivia Magdalena
176505215
DEFINISI
Herpes Zoster atau shingles adalah
penyakit neurokutan dengan
manifestasi erupsi vesikular
berkelompok dengan dasar eritematosa
disertai nyeri radicular unilateral yang
umumnya terbatas di satu dermatom.
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D E R M A
T O M

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Epidemiologi
Risiko meningkat
dengan adanya
keganasan atau
01 inveksi HIV

Insiden dan keparahan 02


penyakitnya
meningkat dengan
bertambahnya usia
Etiopatogenesis
• Mengikuti infeksi primer virus varisela zozter, partikel virus dapat tetap tinggal
di dalam ganglion sensoris saraf spinalis, kranialis atau otonom selama
setahun.

• Saat respon imunitas menurun sampai tiak lagi efekefektif mencegah infeks
virus

• Maka partikel virus virus tersebut mengalami reaktivasi dan menimbulkan


ruam kulit yang terlokalisata di dalam satu dermatom
Gejala Klinis
01 Gejala Prodromal

02 Gejala Konsitusi
Gejala Prodromal
Berkembang Erupsi kulit
jadi papul, mengalami
vesikel jernih involusi

Timbul erupsi Selanjutnya vesikel


kulit berupa menjadi keruh dan
makula akhirnya pecah
kemerahan menjadi krusta
Variasi klinis Herpes Zoster

Zoster sine herpete

Terjadi nyeri segmental yang tidak diikuti dengan erupsi kulit

Herpes zoster abortif

Erupsi kulit hanya berupa eritema dengan atau tanpa vesikel yang
langsung mengalami resolusi sehingga perjalanan penyakutnya
berangsung singkat
Variasi klinis Herpes Zoster

Zoster aberans

Erupsi kulitnya melalui garis tengah

Herpes zoster oftalmikus

Virus menyerang cabang pertama nervus trigeminus


Herpes Zoster
Zoster sine Herpes Zoster Oftalmikus
herpete
Diagnosa Banding
01 Herpes Simpleks

02 Dermatitis herpetiformis
dari Duhring
Diagnosis
• Nucleic acid varicella zoster virus
• Isolasi virus dari sediaan hapus lesi
• Pemeriksaan antibody IgM spesifik
diperlukan
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Mengikuti infeksi
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