 Positive

 Fast
 Comprehensive information
 Negative
 Expensive
 Low coverage
 JAMA
 Therapie
 New Engl J of Med
 Brit Med Journal
 The Lancet
http://bmj.com/
 Pharmacoepidemiology & Drug Safety
 Drug Safety
 Risk & Safety in Medicine
 Positive
Fast
High coverage
 Negative
Minimal detail

Current Contents
 Positive
- Quite fast
- Some detail
- High coverage
 Negative
- Lack of detail
- Difficult to search systematically
- (Cost)
 Reactions Weekly
 Positive
 Meyler's Side Effects
of Drugs
- Assessment of
significance  Side Effects of Drugs
- Easy access Annual
 Negative  Adverse Drug
- Lack of detail Reaction Bulletin
- Not completely  Prescrire
up-to-date
 Expert Opinion on
Drug Safety
 Martindale – the extra Pharmacopoea

 Meyler’s Side Effects of Drugs

 Pharmacovigilance from A-Z

 Dictionary of Pharmacovigilance
 Drug induced diseases
◦ Textbook of Adverse Drug Reactions (Davies, 1998)
◦ Avery's Drug Treatment (Speight, 1997)
◦ Drug Benefits and Risks (van Boxtel, Santoso, Edwards,
2002)
◦ Adverse Drug Reactions (Lee, 2001)
◦ Pharmacovigilance (Mann, Andrews, 2002)
◦ Pharmacoepidemiology (Strom, 2000)
◦ Stephens’ Detection of New Adverse Drug Reactions
(Talbot, Waller, 2004)
◦ Adverse Drug Reactions: A practical guide to Diagnosis
and Management (Bénichou, 1996)
 Adverse Drug Interactions
(Griffin, D'Arcy, 1997)
 Drugs in Pregnancy and
Lactation (Briggs,
Freeman,Yaffe, 1998)
 Drug-induced Ocular Side
Effects (Fraunfelder, 2002)
 Adverse Effects of Herbal
Drugs (De Smet et al 1992)
 Adverse Events Associated
with childhood vaccines
(Instit of Med, 1994)
 Responsibility for Drug-
induced Injury (Dukes,
Mildred, Swartz, 1998)
 Safety of Anaesthetic Drugs
(Naguib, 1998)
 To Heal And Harm: An
economic view on drug
safety (Silcock and Pritchard,
2003)
 Micromedex
◦ Includes Martindale, PDR, Alternative Medicines
and Index Nominum

 Merck Manual
◦ Includes: The Merck Manual of Diagnosis and
Therapy

 SAM=Scientific American Medicine

 Positive
◦ High coverage
◦ High specificity of search
 Negative
◦ Requires equipment & skill
◦ Lack of detail
 Medline
◦ Pubmed is using the MeSH (Medical
Subject Headings) terminology.
 EMBASE
 Current Contents on CD
 Reactions Weekly on-line
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
 WHO Pharmaceuticals Newsletter
 WHO Drug Information

 Dialogue in Pharmacovigilance
 Viewpoint 1 & 2
 Expecting the Worst
 Uppsala Reports
 Presciber Update, New Zealand
 Australian Adverse Reactions Bulletin
 Signals in Adverse Drug Reactions Monitoring,

The Philippines
 Butlletí Groc and many other regional bulletins,

Spain
 Information från Läkemedelsverket, Sweden
 Drug Information Bulletin, Tanzania
 Berita Ubat-Ubatan, Malaysia
 Folia Pharmacoterapeutica, Belgium
 Canadian Adverse Drug Reaction Newsletter
 TABU, Finland
 Drug Safety Newsletter, Ireland
 Information on Adverse Reactions to Drugs,

Japan
 Adverse Drug Reaction News, Singapore