SYMPTOMS Y
Diarrhea
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Pathophysiology
Types of diarrhea include secretory, osmotic, and mixed
diarrhea. Secretory diarrhea is usually high-volume diarrhea
and is caused by increased production and secretion of water
and electrolytes by the intestinal mucosa into the intestinal
lumen. Osmotic diarrhea occurs when water is pulled into the
intestines by the osmotic pressure of unabsorbed particles,
slowing the reabsorption of water. Mixed diarrhea is caused by
increased peristalsis (usually from IBD) and a combination of
increased secretion and decreased absorption in the bowel.
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Statistics
The infectious agents that cause diarrhea are present or are
sporadically introduced throughout the world. Diarrhoea is a rare
occurrence for most people who live in developed countries
where sanitation is widely available, access to safe water is high
and personal and domestic hygiene is relatively good. World-
wide around 1.1 billion people lack access to improved water
sources and 2.4 billion have no basic sanitation. Diarrhoea due to
infection is widespread throughout the developing world. In
Southeast Asia and Africa, diarrhoea is responsible for as much as
8.5% and 7.7% of all deaths respectively.
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Signs and Symptoms
Increased frequency and fluid content of stool
Painful spasmodic contractions of the anus and ineffectual straining (tenesmus) with
each defecation
Other symptoms, depending on the cause and severity and related to dehydration
and fluid and electrolyte imbalances, include the following:
ii. Loose, semisolid stools, which are associated with disorders of the large bowel
iv. Blood, mucus, and pus in the stools, which denote inflammatory enteritis or colitis
v. Oil droplets on the toilet water, which are diagnostic of pancreatic insufficiency
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Prognosis
Many people with symptoms of acute diarrhoea will
improve within 2-4 days: rotavirus diarrhoea usually lasts
3-8 days, norovirus around 2 days and infection
with Campylobacter spp. and Salmonella spp. 2-7
days.
Giardia spp. infection may persist and cause chronic
diarrhoea.
Diarrhoea is the second leading cause of death
worldwide.
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Complications
Complications of diarrhea include cardiac
dysrhythmias due to fluid and electrolyte (potassium)
imbalance, urinary output less than 30 mL/h, muscle
weakness, paresthesia, hypotension, anorexia,
drowsiness (report if potassium level is less than 3.5
mEq/L [3.5 mmol/L]), skin care issues related to irritant
dermatitis, and death if imbalances become severe.
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Diagnostic
When the cause is not obvious:
i. Complete blood cell count
ii. Serum chemistries
iii. Urinalysis
iv. Routine stool examination
v. Stool examinations for infectious or parasitic organisms,
bacterial toxins, blood, fat, electrolytes, and white blood cells
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Treatment / Medical Management
Primary medical management is directed at controlling
symptoms, preventing complications, and eliminating or treating
the underlying disease.
Certain medications (eg, antibiotics, anti-inflammatory agents)
and antidiarrheals (eg, loperamide [Imodium], diphenoxylate
[Lomotil]) may reduce the severity of diarrhea and the disease.
Increase oral fluids; oral glucose and electrolyte solution may be
prescribed.
Antimicrobials are prescribed when the infectious agent has been
identified or diarrhea is severe.
IV therapy is used for rapid hydration in very young or elderly
patients.
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Prevention
Safe water/ Adequate Sanitation - Treat water before
use and dispose of waste safely
Routine Vaccination- Provide rotavirus vaccine
Improved hygiene- Wash hands when appropriate
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Nursing Diagnosis
Diarrhea may be related to inflammation, irritation; infectious process, parasites;
Malabsorption; Laxative or alcohol abuse, toxins, contaminants; Adverse effects
of pharmaceutical agents, radiation; Tube feedings; Travel
Risk for deficient Fluid Volume related to excessive losses through gastrointestinal
tract.
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Nursing Interventions
Elicit a complete health history to identify character and pattern of diarrhea, and the following:
any related signs and symptoms, current medication therapy, daily dietary patterns and intake,
past related medical and surgical history, and recent exposure to an acute illness or travel to
another geo- graphic area.
Inspect mucous membranes and skin to determine hydration status, and assess perianal area.
Encourage bed rest, liquids, and foods low in bulk until acute period subsides.
Encourage patient to limit intake of caffeine and carbonated beverages, and avoid very hot
and cold foods because these increase intestinal motility.
Advise patient to restrict intake of milk products, fat, whole grain products, fresh fruits, and
vegetables for several days.