Geneva, Switzerland

WHO Guideline on
Antenatal Care (2016)
Overview

1
 ANC is critical

Through timely and appropriate evidence-based

actions related to health promotion, disease
prevention, screening, and treatment

 Reduces complications  Reduces stillbirths and

from pregnancy and perinatal deaths
childbirth

 Integrated care delivery throughout pregnancy

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 A positive pregnancy experience is defined as:

 maintaining physical and sociocultural

normality
 maintaining a healthy pregnancy for
mother and baby (including preventing
and treating risks, illness and death)
 having an effective transition to positive
labor and birth, and achieving positive
motherhood (including maternal self-
esteem, competence and autonomy)

3 Filename
 Previously: The 4-visit
WHO ANC model
 Involves specific evidence-
based interventions for all
women

 Carried out at four critical

times

 Also known as the Focused

Antenatal Care Model (FANC)

 Part of Pregnancy, Childbirth,

Postpartum and Newborn
Care (PCPNC)

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 QUALITY throughout the continuum of care
WHO envisions a world where “every pregnant woman and newborn receives
quality care throughout the pregnancy, childbirth and the postnatal period”.

 Prioritizes person-centred
health and well-being:

 Reducing mortality and

morbidity

 Providing respectful care that

takes into account woman’s
views

 Optimizing service delivery

within health systems

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Box 5: Comparing ANC schedules
WHO FANC
model
2016 WHO ANC
model
First trimester
Visit 1: 8–12 weeks Contact 1: up to 12 weeks
Second trimester
Visit 2: 24–26 weeks
Contact 2: 20 weeks
Contact 3: 26 weeks
Third trimester
Visit 3: 32 weeks
Visit 4: 36–38 weeks
Contact 4: 30 weeks
Contact 5: 34 weeks
Contact 6: 36 weeks
Contact 7: 38 weeks
Contact 8: 40 weeks
Return for delivery at 41 weeks if not given birth.
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 DEVELOPMENT OF THE GUIDELINE

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 Recommendations on ANC
49 recommendations were grouped into five
topic areas:
A. Nutritional interventions (14)
B. Maternal and fetal assessment (13)
C. Preventive measures (7)
D. Interventions for common physiological
symptoms (6)
E. Health systems interventions to improve
the utilization and quality of ANC (9)
Including 10 recommendations relevant to
routine ANC from other WHO guidelines
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 Examples
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 RECOMMENDATIONS

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 A. Nutritional interventions - 1
A.1.1: Counselling about healthy eating and keeping physically active Recommended
during pregnancy is recommended for pregnant women to stay
healthy and to prevent excessive weight gain during pregnancy.

A.1.2: In undernourished populations, nutrition education on Context-specific

increasing daily energy and protein intake is recommended for recommendation
pregnant women to reduce the risk of low-birth-weight neonates.
A.1.3: In undernourished populations, balanced energy and protein Context-specific
dietary supplementation is recommended for pregnant women to recommendation
reduce the risk of stillbirths and small-for-gestational-age neonates.

A.1.4: In undernourished populations, high-protein supplementation Not recommended

is not recommended for pregnant women to improve maternal and
perinatal outcomes.

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 A. Nutritional interventions -2
A.2.1: Daily oral iron and folic acid supplementation with 30 mg to Recommended
60 mg of elemental iron and 400 µg (0.4 mg) of folic acid is
recommended for pregnant women to prevent maternal anaemia,
puerperal sepsis, low birth weight, and preterm birth.
A.2.2: Intermittent oral iron and folic acid supplementation with 120 Context-specific
mg of elemental iron and 2800 µg (2.8 mg) of folic acid once weekly is recommendation
recommended for pregnant women to improve maternal and neonatal
outcomes if daily iron is not acceptable due to side-effects, and in
populations with an anaemia prevalence among pregnant women of
less than 20%.
A.3: In populations with low dietary calcium intake, daily calcium Context-specific
supplementation (1.5–2.0 g oral elemental calcium) is recommended recommendation
for pregnant women to reduce the risk of pre-eclampsia.

A.4: Vitamin A supplementation is only recommended for pregnant Context-specific

women in areas where vitamin A deficiency is a severe public health recommendation
problem, to prevent night blindness.

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 Nutritional interventions - 3
A.5: Zinc supplementation for pregnant women is only recommended Context-specific
in the context of rigorous research. recommendation
(research)
A.6: Multiple micronutrient supplementation is not recommended for Not recommended
pregnant women to improve maternal and perinatal outcomes.

A.7: Vitamin B6 (pyridoxine) supplementation is not recommended Not recommended

for pregnant women to improve maternal and perinatal outcomes.

A.8: Vitamin E and C supplementation is not recommended for Not recommended

pregnant women to improve maternal and perinatal outcomes.

A.9: Vitamin D supplementation is not recommended for pregnant Not recommended

women to improve maternal and perinatal outcomes.

A.10: For pregnant women with high daily caffeine intake (more than Context-specific
300 mg per day), lowering daily caffeine intake during pregnancy is recommendation
recommended to reduce the risk of pregnancy loss and low-birth-
weight neonates.
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 B.1. Maternal assessment - 1
B.1.1: Full blood count testing is the recommended method for Context-specific
diagnosing anaemia in pregnancy. In settings where full blood count recommendation
testing is not available, on-site haemoglobin testing with a
haemoglobinometer is recommended over the use of the haemoglobin
colour scale as the method for diagnosing anaemia in pregnancy.
B.1.2: Midstream urine culture is the recommended method for Context-specific
diagnosing asymptomatic bacteriuria (ASB) in pregnancy. In settings recommendation
where urine culture is not available, on-site midstream urine Gram-
staining is recommended over the use of dipstick tests as the method
for diagnosing ASB in pregnancy.

B.1.3: Clinical enquiry about the possibility of intimate partner Context-specific

violence (IPV) should be strongly considered at antenatal care visits recommendation
when assessing conditions that may be caused or complicated by IPV
in order to improve clinical diagnosis and subsequent care, where
there is the capacity to provide a supportive response (including
referral where appropriate) and where the WHO minimum
requirements are met.
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 B.1. Maternal assessment - 2
B.1.4: Hyperglycaemia first detected at any time during pregnancy should be Recommended
classified as either gestational diabetes mellitus (GDM) or diabetes mellitus in
pregnancy, according to WHO criteria.

B.1.5: Health-care providers should ask all pregnant women about their tobacco Recommended
use (past and present) and exposure to second-hand smoke as early as possible in
the pregnancy and at every antenatal care visit.

B.1.6: Health-care providers should ask all pregnant women about their use of Recommended
alcohol and other substances (past and present) as early as possible in the
pregnancy and at every antenatal care visit.
B.1.7: In high-prevalence settings, provider-initiated testing and counselling (PITC) Recommended
for HIV should be considered a routine component of the package of care for
pregnant women in all antenatal care settings. In low-prevalence settings, PITC can
be considered for pregnant women in antenatal care settings as a key component
of the effort to eliminate mother-to-child transmission of HIV, and to integrate HIV
testing with syphilis, viral or other key tests, as relevant to the setting, and to
strengthen the underlying maternal and child health systems.
B.1.8: In settings where the tuberculosis (TB) prevalence in the general population Context-specific
is 100/100 000 population or higher, systematic screening for active TB should be recommendation
15 considered for pregnant women as part of antenatal care.
 B.2.Fetal assessment
B.2.1: Daily fetal movement counting, such as with “count-to-ten” kick Context-specific
charts, is only recommended in the context of rigorous research. recommendation
(research)
B.2.2: Replacing abdominal palpation with symphysis-fundal height Context-specific
(SFH) measurement for the assessment of fetal growth is not recommendation
recommended to improve perinatal outcomes. A change from what is
usually practiced (abdominal palpation or SFH measurement) in a
particular setting is not recommended.

B.2.3: Routine antenatal cardiotocography is not recommended for Not recommended

pregnant women to improve maternal and perinatal outcomes.

B.2.4: One ultrasound scan before 24 weeks of gestation (early Recommended

ultrasound) is recommended for pregnant women to estimate
gestational age, improve detection of fetal anomalies and multiple
pregnancies, reduce induction of labour for post-term pregnancy, and
improve a woman’s pregnancy experience.
B.2.5: Routine Doppler ultrasound examination is not recommended for Not recommended
pregnant women to improve maternal and perinatal outcomes.
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 C. Preventive measures - 1
C.1: A seven-day antibiotic regimen is recommended for all pregnant Recommended
women with asymptomatic bacteriuria (ASB) to prevent persistent
bacteriuria, preterm birth and low birth weight.

C.2: Antibiotic prophylaxis is only recommended to prevent recurrent Context-specific

urinary tract infections in pregnant women in the context of rigorous recommendation
research. (research)
C.3: Antenatal prophylaxis with anti-D immunoglobulin in non-sensitized Context-specific
Rh-negative pregnant women at 28 and 34 weeks of gestation to prevent recommendation
RhD alloimmunization is only recommended in the context of rigorous (research)
research.
C.4: In endemic areas, preventive anthelminthic treatment is Context-specific
recommended for pregnant women after the first trimester as part of recommendation
worm infection reduction programmes.
C.5: Tetanus toxoid vaccination is recommended for all pregnant women, Recommended
depending on previous tetanus vaccination exposure, to prevent
neonatal mortality from tetanus.

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 C. Preventive measures - 2
C.6: In malaria-endemic areas in Africa, intermittent preventive Context-specific
treatment with sulfadoxine-pyrimethamine (IPTp-SP) is recommended recommendation
for all pregnant women. Dosing should start in the second trimester, and
doses should be given at least one month apart, with the objective of
ensuring that at least three doses are received.

C.7: Oral pre-exposure prophylaxis (PrEP) containing tenofovir disoproxil Context-specific

fumarate (TDF) should be offered as an additional prevention choice for recommendation
pregnant women at substantial risk of HIV infection as part of
combination prevention approaches.

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 D. Common physiological symptoms
D.1: Ginger, chamomile, vitamin B6 and/or acupuncture are recommended for the relief Recommended
of nausea in early pregnancy, based on a woman’s preferences and available options.

D.2: Advice on diet and lifestyle is recommended to prevent and relieve heartburn in Recommended
pregnancy. Antacid preparations can be offered to women with troublesome symptoms
that are not relieved by lifestyle modification.
D.3: Magnesium, calcium or non-pharmacological treatment options can be used for the Recommended
relief of leg cramps in pregnancy, based on a woman’s preferences and available options.
D.4: Regular exercise throughout pregnancy is recommended to prevent low back and Recommended
pelvic pain. There are a number of different treatment options that can be used, such as
physiotherapy, support belts and acupuncture, based on a woman’s preferences and
available options.
D.5: Wheat bran or other fibre supplements can be used to relieve constipation in Recommended
pregnancy if the condition fails to respond to dietary modification, based on a woman’s
preferences and available options.
D.6: Non-pharmacological options, such as compression stockings, leg elevation and Recommended
water immersion, can be used for the management of varicose veins and oedema in
pregnancy, based on a woman’s preferences and available options.
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 E. Health systems interventions to improve the
utilization and quality of ANC – 1
E.1: It is recommended that each pregnant woman carries her own case Recommended
notes during pregnancy to improve continuity, quality of care and her
pregnancy experience.

E.2: Midwife-led continuity-of-care models, in which a known midwife or Context-specific

small group of known midwives supports a woman throughout the recommendation
antenatal, intrapartum and postnatal continuum, are recommended for
pregnant women in settings with well functioning midwifery programmes.
E.3: Group antenatal care provided by qualified health-care professionals Context-specific
may be offered as an alternative to individual antenatal care for pregnant recommendation
women in the context of rigorous research, depending on a woman’s (research)
preferences and provided that the infrastructure and resources for delivery
of group antenatal care are available.

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 E. Health systems interventions to improve the
utilization and quality of ANC – 2
E.4.1: The implementation of community mobilization through facilitated Context-specific
participatory learning and action (PLA) cycles with women’s groups is recommendation
recommended to improve maternal and newborn health, particularly in rural
settings with low access to health services. Participatory women’s groups
represent an opportunity for women to discuss their needs during pregnancy,
including barriers to reaching care, and to increase support to pregnant
women.

E.4.2: Packages of interventions that include household and community Context-specific

mobilization and antenatal home visits are recommended to improve recommendation
antenatal care utilization and perinatal health outcomes, particularly in rural
settings with low access to health services.

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 E. Health systems interventions to improve the
utilization and quality of ANC – 3

E.5.1: Task shifting the promotion of health-related behaviours for maternal Recommended
and newborn health to a broad range of cadres, including lay health workers,
auxiliary nurses, nurses, midwives and doctors is recommended.

E.5.2: Task shifting the distribution of recommended nutritional Recommended

supplements and intermittent preventative treatment in pregnancy (IPTp)
for malaria prevention to a broad range of cadres, including auxiliary nurses,
nurses, midwives and doctors is recommended.

E.6: Policy-makers should consider educational, regulatory, financial, and Context-specific

personal and professional support interventions to recruit and retain recommendation
qualified health workers in rural and remote areas.

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 E. Health systems interventions to improve the
utilization and quality of ANC – 4

E.7: Antenatal care models with a minimum of eight contacts are Recommended
recommended to reduce perinatal mortality and improve women’s
experience of care.

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 IMPORTHANT OF IDENTIFYING HIGH RISK
PREGNANCY – TO READY FOR EXTRA MEDICAL
ATTENTION .
 RISK FACTOR
 EXISTING HEALTH
CONDITIONS
• HIGH BLOOD PRESSURE
• POLYCYSTIC OVARIAN DISEASES
• DIABETES
• KIDNEY DISEASES
• AUTOIMMUNE DISEASES
• THYROID DISEASES
• INFERTILITY
• OBESITY
• HIV/HIDS
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AGE
• TEEN PREGNANCY
• FIRST PREGNANCY AFTER 35
• LIFESTYLE
• ALCOHOL USE
• CIGRATTE SMOKING
• CONDITION OF PREGNANCY
• MULTIPLE PREGNANCY
• GESTATIONAL DIABETES
• PREECLAMPSIA AND
ECLAMPSIA
• ETC ..
 NEW BORN CARE

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 4 CORE STEPS

 IMMEDIATE AND THROUGH DRYING

 EARLY SKIN TO SKIN CONTACT
 PROPER TIMED CORD CLAMPING
 NON-SEPARATION OF MOTHER AND NEW BORN FOR
EARLY BREASTFEEDING

26 Filename
 WHAT'S NEW?

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28 Filename
 E.7: Antenatal care models with a minimum of eight contacts
are recommended to reduce perinatal mortality and improve
1
women’s experience of care.
This GDG recommendation was informed by:
 Evidence suggesting increased perinatal deaths in 4-visit ANC
model
 Evidence supporting improved safety during pregnancy through
increased frequency of maternal and fetal assessment to detect
complications
 Evidence supporting improved health system communication and
support around pregnancy for women and families
 Evidence indicating that more contact between pregnant women
and respectful, knowledgeable health care workers is more likely to
lead to a positive pregnancy experience
 Evidence from HIC studies indicating no important differences in
maternal and perinatal health outcomes between ANC models that
included at least eight contacts and ANC models that included 11 to
15 contacts.
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 2016 WHO ANC model

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 2
Contact versus visit

 The guideline uses the term ‘contact’ - it implies an active

connection between a pregnant woman and a health care
provider that is not implicit with the word ‘visit’.
– quality care including medical care, support and timely and relevant
information

 In terms of the operationalization of this recommendation,

‘contact’ can take place at the facility or at community level
– be adapted to local context through health facilities or community
outreach services

 ‘Contact’ helps to facilitate context-specific recommendations

– Interventions (such as malaria, tuberculosis)
– Health system (such as task shifting)

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 3
Early ultrasound
 In the new WHO ANC guideline, an ultrasound scan before 24 weeks’ gestation is
recommended for all pregnant women to:
 estimate gestational age
 detect fetal anomalies and multiple pregnancies
 enhance the maternal pregnancy experience

 An ultrasound scan after 24 weeks’ gestation (late ultrasound) is not

recommended for pregnant women who have had an early ultrasound scan.
– Stakeholders should consider offering a late ultrasound scan to pregnant women who
have not had an early ultrasound scan.

 Ultrasound equipment can also used for other indications (e.g. obstetric
emergencies) or by other medical departments

 The implementation and impact of this recommendation on health outcomes,

facility utilization, and equity should be monitored at the health service, regional,
and country level
– based on clearly defined criteria and indicators associated with locally agreed and
appropriate targets.

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 4
ANC model – positive pregnancy experience

Overarching aim

To provide pregnant women with respectful,

individualized, person-centred care at every contact,
with implementation of effective clinical practices
(interventions and tests), and provision of relevant
and timely information, and psychosocial and
emotional support, by practitioners with good
clinical and interpersonal skills within a
well functioning health system.

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 5
Effective implementation of ANC requires
 Health systems approach and strengthening
o Continuity of care
o Integrated service delivery
o Improved communication with, and support for
women
o Availability of supplies and commodities
o Empowered health care providers
 Recruitment and retention of staff in rural and remote
areas
 Capacity building

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 IMPLEMENTATION AND DISSEMINATION

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 Implementation, research and M&E - 1

 Adoption, adaptation and implementation of the

ANC model
– Essential core package of ANC that all pregnant women
and adolescent girls should receive
– With the flexibility to employ different options based on
the context and needs of different countries
 What is the content of the model/package?
 Who provides care?
 Where is the care provided?
 How is the care provided to meet the needs of the users?

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 Implementation, research and M&E – 2

 Implementation considerations

 Throughout adaptation and implementation at country

level – monitoring and evaluation (M&E) and learning
will be crucial

 Development of indicators

 Priority research questions

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 Dissemination

 Policy briefs  Regional dissemination

– ANC model workshops
– Early USG  Translation of the
– Others (in the works) guideline
 Interactive website  Webinar
 Tools for
implementation

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 Relevant links – 1

About the guidelines:

www.who.int/reproductivehealth/news/ant
enatal-care/en/index.html

South Africa story from the field:

www.who.int/reproductivehealth/news/ant
enatal-care-south-africa/en/index.html

The guideline
www.who.int/reproductivehealth/publicati
ons/maternal_perinatal_health/anc-
positive-pregnancy-experience/en/

Press release
www.who.int/entity/mediacentre/news/rel
eases/2016/antenatal-care-
guidelines/en/index.html

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 Relevant links – 2

Infographics
www.who.int/reproductiv
ehealth/publications/mat
ernal_perinatal_health/A
NC_infographics/en/index
.html
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 Many thanks to…
 WHO Steering Group
– A. Metin Gülmezoglu (RHR), Matthews
Mathai (MCA), Olufemi Oladapo (RHR), Juan
Pablo Peña-Rosas (NHD), Ӧzge Tunçalp (RHR)
 Members of the GDG
– Mohammed Ariful Aram, Françoise Cluzeau,
Luz Maria De-Regil, Aft Ghérissi, Gill Gyte,
Rintaro Mori, James Neilson, Lynnette
Neufeld, Lisa Noguchi, Nafissa Osman, Erika
Ota, Tomas Pantoja, Bob Pattinson, Kathleen
Rasmussen, Niveen Abu Rmeileh, Harshpal
Singh Sachdev, Rusidah Selamat, Charlotte
Warren, Charles Wisonge and James Neilson
 WHO regional advisors
– Karima Gholbzouri, Gunta Lazdane, Bremen
de Mucio, Mari Nagai, Leopold Ouedraogo,
Neena Raina and Susan Serruya
 Technical contributions (incl scoping)
– Manzi Anatole, Rifat Atun, Himanshu
Bhushan, Jacquelyn Caglia, Chompilas
Chongsomchai, Morseda Chowdhury,
Mengistu Hailemariam, Stephen Hodgins,
Annie Kearns, Rajat Khosla, Ana Langer,
Pisake Lumbiganon, Taiwo Oyelade, Jeffrey
Smith, Petra ten Hoope-Bender, James Tielsch
41 and Rownak Khan
 Internal and external reviewers
– Andrea Bosman, Maurice Bucagu, Jahnavi
Daru, Claudia Garcia-Moreno, Haileyesus
Getahun, Rodolfo Gomez, Tracey Goodman,
Tamar Kabakian, Avinash Kanchar, Philipp
Lambach, Sarah de Masi, Frances McConville,
Antonio Montresor, Justin Ortiz, Anayda
Portela, Jeremy Pratt, Lisa Rogers, Nathalie
Roos, Silvia Schwarte, Maria Pura Solon, João
Paulo Souza, Petr Velebil , Ahmadu Yakubu,
Yacouba Yaro, Teodora Wi and Gerardo
Zamora
 Observers
– France Donnay (BMGF), Rita Borg-Xuereb
(ICM), Diogo Ayres-de-Campos and CN
Purandare (FIGO), Luc de Bernis (UNFPA),
Roland Kupka (UNICEF), Deborah Armbruster
and Karen Fogg (USAID)
 WHO ANC Technical Working Group
– Edgardo Abalos, Emma Allanson, Monica
Chamillard, Virginia Diaz , Soo Downe, Kenny
Finlayson, Claire Glenton, Ipek Gurol-Urganci,
Sonja Henderson, Frances Kellie, Khalid Khan,
Theresa Lawrie, Simon Lewin, Nancy Medley,
Jenny Moberg, Charles O'Donovan, Ewelina
Rogozinska and Inger Scheel
 "To achieve the Every Woman Every Child vision and the Global Strategy for
Women's Children's and Adolescents' Health, we need innovative, evidence-
based approaches to antenatal care. I welcome these guidelines, which aim to
put women at the centre of care, enhancing their experience of pregnancy and
ensuring that babies have the best possible start in life."

Ban Ki-moon, UN Secretary-General

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